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PHL82880

Nordihydroguaiaretic acid

phyproof® Reference Substance

Synonym(s):

1,4-Bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane, 4,4′-(2,3-Dimethyltetramethylene)dipyrocatechol, Masoprocol, NDGA

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PHL82880-50MG

$178.40

$178.40

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About This Item

Linear Formula:
[-CH(CH3)CH2C6H3-1,2-(OH)2]2
CAS Number:
500-38-9
Molecular Weight:
302.36
Beilstein/REAXYS Number:
2056826
MDL number:
MFCD00002206
UNSPSC Code:
41116107
NACRES:
NA.24

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grade

primary reference standard

product line

phyproof® Reference Substance

assay

≥98.0% (HPLC)

manufacturer/tradename

PhytoLab

mp

184-186 °C (lit.)

application(s)

food and beverages

format

neat

SMILES string

CC(Cc1ccc(O)c(O)c1)C(C)Cc2ccc(O)c(O)c2

InChI

1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3

InChI key

HCZKYJDFEPMADG-UHFFFAOYSA-N

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1 of 4

This Item
PHR350974540479975
Nordihydroguaiaretic acid phyproof® Reference Substance

PHL82880

Nordihydroguaiaretic acid

Nordihydroguaiaretic Acid certified reference material, pharmaceutical secondary standard

Supelco

PHR3509

Nordihydroguaiaretic Acid

Nordihydroguaiaretic acid ≥97.0% (HPLC)

Sigma-Aldrich

74540

Nordihydroguaiaretic acid

NDGA A cell-permeable antioxidant and a selective lipoxygenase (LOX) inhibitor (IC50 = 200 nM, 30 µM, and 30 µM for 5-LOX, 12-LOX, and 15-LOX, respectively) over cyclooxygenase (IC50 = 100 µM).

Sigma-Aldrich

479975

NDGA

grade

primary reference standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

-

format

neat

format

-

format

-

format

-

product line

phyproof® Reference Substance

product line

-

product line

-

product line

-

assay

≥98.0% (HPLC)

assay

-

assay

≥97.0% (HPLC)

assay

≥90% (HPLC)

manufacturer/tradename

PhytoLab

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

Calbiochem®

mp

184-186 °C (lit.)

mp

184-186 °C (lit.)

mp

184-186 °C (lit.)

mp

-

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Lipoxygenase inhibitor; polyphenol-bearing o-dihydroxy (catechol) structure.

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
191004
100530090

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