PHL89263

Quercetin dihydrate

phyproof^® Reference Substance

• Synonym(s): 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate, 3,3′,4′,5,7-Pentahydroxyflavone dihydrate
• Empirical Formula (Hill Notation): C₁₅H₁₀O₇ · 2H₂O
• CAS Number: 6151-25-3
• Molecular Weight: 338.27
• NACRES: NA.24
• UNSPSC Code: 41116107
• Colour Index Number: 75670
• Beilstein/REAXYS Number: 317313

Properties

• SMILES string: OC(C(O)=C1)=CC=C1C2=C(O)C(C3=C(O)C=C(O)C=C3O2)=O
• InChI key: GMGIWEZSKCNYSW-UHFFFAOYSA-N
• InChI: 1S/C15H10O7.2H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;;/h1-5,16-19,21H;2*1H2
• grade: primary reference standard
• product line: phyproof^® Reference Substance
• assay: ≥95.0% (HPLC)
• form: powder
• manufacturer/tradename: PhytoLab
• mp: >300 °C (lit.)

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Quercetin dihydrate is a flavonoid with anticancer activity.

Quercetin dihydrate is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.

Other Notes

This compound is commonly found in plants of the genus: angelica arnica carum echinacea eucalyptus ginkgo glycyrrhiza hypericum lycium pimpinella primula sambucus silybum

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• pictograms: GHS06
• signalword: Danger
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 1
• hcodes: H301,H315,H319
• pcodes: P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2