There is no assigned value but the butyl septum has ultra-low permeability. It can be used with many organic solvents: acetic acid (<50%), acetonitrile, acetone, alcohols, DMSO, phenol. Not compatible with alkanes, benzene, carbon disulfide, chlorinated solvents, cyclohexane. It has a maximum temperature of 200 °C.
SU860011
Crimp seal with PTFE/butyl septum (Pharma-Fix)
aluminum seal (with 10 mm center hole), PTFE-faced butyl septum, diam. × thickness 20 mm × 3.0 mm, pkg of 100 ea
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material
PTFE-faced butyl septum
aluminum seal (with 10 mm center hole)
hardness
50 (Durometer: shore A)
packaging
pkg of 100 ea
O.D.
20 mm
diam. × thickness
20 mm × 3.0 mm
fitting
thread for 20 mm
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This Item | 27229 | 508489 | 27452 |
|---|---|---|---|
| O.D. 20 mm | O.D. 20 mm | O.D. 20 mm | O.D. - |
| fitting thread for 20 mm | fitting thread for 20 mm | fitting thread for 20 mm | fitting thread for 13 |
| material PTFE-faced butyl septum, aluminum seal (with 10 mm center hole) | material silver aluminum seal, white PTFE/silicone | material PTFE/silicone (blue silicone), aluminum seal (open center) | material PTFE/silicone septum, silver aluminum seal (open center) |
| hardness 50 (Durometer: shore A) | hardness - | hardness - | hardness - |
| packaging pkg of 100 ea | packaging pkg of 100 ea | packaging pkg of 100 ea | packaging pkg of 100 ea |
| diam. × thickness 20 mm × 3.0 mm | diam. × thickness - | diam. × thickness 20 mm × 2.9 mm | diam. × thickness - |
Application
Crimp seal with PTFE/butyl septum (Pharma-Fix) may be used to seal standard residual solvents for the determination of residual solvents in drug substances using headspace gas-chromatography coupled with flame ionization detector (HS-GC-FID).[1]
PTFE-faced butyl septum was used in sealing headspace vials to analyse the sampling efficiency and breakthrough of methyl bromide on activated charcoal using GC.[2] It was also used for sealing water samples during headspace analysis with GC-FID, in a study which demonstrates cross-validation of methods used for methyl-tert-butyl ether (MTBE) analysis.[3]
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Cross-validation of methods used for analysis of MTBE and other gasoline components in groundwater.
Lacorte, S., et al.
Chromatographia, 56, 739-744 (2002)
Measuring residual solvents in pharmaceutical samples using fast gas chromatography techniques.
Rocheleau J-M, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 805(1), 77-86 (2004)
Sampling and stability of methyl bromide on activated charcoal.
Gan, Jianying, et al.
Journal of Agricultural and Food Chemistry, 43, 1361-1367 (1995)
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