Y0002040

Calcifediol for impurity D identification

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): 25-Hydroxycholecalciferol, 25-Hydroxyvitamin D₃
• Empirical Formula (Hill Notation): C₂₇H₄₄O₂
• CAS Number: 19356-17-3
• Molecular Weight: 400.64
• MDL number: MFCD00867077
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• biological source: synthetic
• grade: pharmaceutical primary standard
• agency: EP
• API family: calcifediol
• form: solid
• manufacturer/tradename: EDQM
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C
• InChI: 1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
• InChI key: JWUBBDSIWDLEOM-DTOXIADCSA-N
• Gene Information: human ... VDR(7421)

Description

General description

Calcifediol is a metabolite of vitamin D₃, which is responsible for maintaining appropriate amounts of calcium and phosphorus for strong as well as healthy teeth and bones.[1][1]

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Calcifediol for impurity D identification may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.[2]

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301 + H311,H330,H372
• pcodes: P260 - P280 - P284 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable