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1003009

USP

Acetaminophen

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
Acetaminophen, 4′-Hydroxyacetanilide, 4-Acetamidophenol, N-(4-Hydroxyphenyl)acetamide, N-Acetyl-4-aminophenol, APAP, Paracetamol
Linear Formula:
CH3CONHC6H4OH
CAS Number:
Molecular Weight:
151.16
Beilstein:
2208089
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

acetaminophen, paracetamol

manufacturer/tradename

USP

mp

168-172 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CC(=O)Nc1ccc(O)cc1

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

InChI key

RZVAJINKPMORJF-UHFFFAOYSA-N

Gene Information

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1 of 4

This Item
A7085A3035BP371
Acetaminophen United States Pharmacopeia (USP) Reference Standard

USP

1003009

Acetaminophen

-
Acetaminophen BioXtra, ≥99.0%

Sigma-Aldrich

A7085

Acetaminophen

Premium Grade
Acetaminophen analytical standard

Sigma-Aldrich

A3035

Acetaminophen

-
Paracetamol British Pharmacopoeia (BP) Reference Standard

BP371

Paracetamol

-
manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

BP

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

application(s)

pharmaceutical

format

neat

format

-

format

-

format

neat

API family

acetaminophen, paracetamol

API family

-

API family

-

API family

acetaminophen, paracetamol

mp

168-172 °C (lit.)

mp

168-172 °C (lit.)

mp

168-172 °C (lit.)

mp

168-172 °C (lit.)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Acetaminophen USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Acetaminophen Tablets
  • Acetaminophen Capsules
  • Acetaminophen Suppositories
  • Acetaminophen Oral Suspension
  • Acetaminophen Oral Solution
  • Acetaminophen and Caffeine Tablets
  • Acetaminophen Extended-Release Tablets

Analgesic.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

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Description
Pricing

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

364.3 °F - Pensky-Martens closed cup

Flash Point(C)

184.6 °C - Pensky-Martens closed cup


Certificates of Analysis (COA)

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Acetaminophen
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(6), 38-38 (2020)
Acetaminophen capsules
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 45(3), 40-40 (2014)
Acetaminophen tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(3), 45-45 (2021)
Acetaminophen Suppositories
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(5), 44-44 (2016)
Mitchell R McGill et al.
Pharmaceutical research, 30(9), 2174-2187 (2013-03-07)
Acetaminophen (APAP) is one of the most widely used drugs. Though safe at therapeutic doses, overdose causes mitochondrial dysfunction and centrilobular necrosis in the liver. The first studies of APAP metabolism and activation were published more than 40 years ago.

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