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MilliporeSigma

1075305

USP

Bisdesmethoxycurcumin

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione

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About This Item

Empirical Formula (Hill Notation):
C19H16O4
CAS Number:
33171-05-0
Molecular Weight:
308.33
MDL number:
MFCD03419284
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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grade

pharmaceutical primary standard

API family

curcumin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

Storage temp.

−20°C

SMILES string

Oc1ccc(cc1)\C=C\C(=O)CC(=O)\C=C\c2ccc(cc2)O

InChI

1S/C19H16O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-12,20-21H,13H2/b11-5+,12-6+

Inchi Key

PREBVFJICNPEKM-YDWXAUTNSA-N

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1 of 4

This Item
PHR3434PHL8958290594
USP

USP

1075305

Bisdesmethoxycurcumin

Bisdesmethoxycurcumin certified reference material, pharmaceutical secondary standard

Supelco

PHR3434

Bisdesmethoxycurcumin

Bisdemethoxycurcumin phyproof® Reference Substance

PHL89582

Bisdemethoxycurcumin

Bisdemethoxycurcumin analytical standard

Supelco

90594

Bisdemethoxycurcumin

manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

PhytoLab

manufacturer/tradename

-

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

primary reference standard

grade

analytical standard

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical

application(s)

food and beverages

application(s)

food and beverages

format

neat

format

-

format

neat

format

neat

API family

curcumin

API family

-

API family

-

API family

-

storage temp.

−20°C

storage temp.

-10 to -25°C

storage temp.

-

storage temp.

-

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bisdesmethoxycurcumin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Curcuminoids
  • Curcuminoids Capsules
  • Curcuminoids Tablets
  • Powdered Turmeric
  • Powdered Turmeric Extract
  • Turmeric

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Sudha Ponnusamy et al.
Food chemistry, 135(4), 2638-2642 (2012-09-18)
Curcuma longa rhizome is used extensively in culinary preparations in Far East and South-East Asia. Health benefits of curcuminoids from C. longa as antioxidants, anti-cancer and anti-inflammatory molecules have been well documented. We report here for the first time that
J R Cashman et al.
Neuro-degenerative diseases, 10(1-4), 274-276 (2011-12-14)
Neurodegenerative diseases are associated with accumulation of modified proteins or peptides including amyloid-β (Aβ) in Alzheimer's disease (AD), and misfolded superoxide dismutase-1 (SOD-1) in amyotrophic lateral sclerosis (ALS). Clearance of Aβ or SOD-1 by the innate immune system may be
Dong-Chan Kim et al.
BMB reports, 45(4), 221-226 (2012-04-26)
Curcumin, a polyphenol responsible for the yellow color of the curry spice turmeric, possesses antiinflammatory, antiproliferative and antiangiogenic activities. However, anticoagulant activities of curcumin have not been studied. Here, the anticoagulant properties of curcumin and its derivative (bisdemethoxycurcumin, BDMC) were
Y-L Liu et al.
Current cancer drug targets, 11(9), 1098-1110 (2011-09-22)
Hypermethylation of the Wnt inhibitory factor-1 (WIF-1) promoter has been implicated in the overactivation of the Wnt pathway in human lung cancer. Curcuminoids exert anti-cancer effects and have been reported to act as hypomethylating agents. Previously, we have investigated and
Ying-Bo Li et al.
Pharmacological reports : PR, 65(3), 700-709 (2013-08-21)
Bisdemethoxycurcumin (BDMC) is a natural derivative of curcumin present in the phenolic components extracted from the dried rhizome of Curcuma longa L. BDMC demonstrated potential chemotherapeutic activities but the underlying mechanisms have not been fully clarified. In the present study
View All Related Papers

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