1076192

BSA for protein quantitation

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Bovine Serum Albumin, Albumin bovine serum, BSA, Bovine albumin
• CAS Number: 9048-46-8
• MDL number: MFCD00130384
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• mol wt: ~66 kDa
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C

Description

General description

Shipping condition: wet ice

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

BSA for protein quantitation USP reference standard in specified compendial tests and assays.

Also used to prepare standard and suitability standard solutions during the determination of total protein in pharmaceutical drug substances and products according to the United States Pharmacopeia (USP) general chapter.

Biochem/physiol Actions

Certain conformational and primary-sequence epitopes of BSA are suspected allergens in human beef and milk allergies.

Preparation Note

Serum albumin may be referred to as Fraction V. This naming convention is taken from the original Cohn method of fractionating serum proteins using cold ethanol precipitation. Serum albumin was found in the fifth ethanol fraction using Cohn′s method. Since then, the term "Fraction V" has been used by some to describe serum albumin regardless of the method of preparation. Others have used this term to describe serum albumin purified by ethanol fractionation methods that have been highly modified since the original Cohn method was described. Sigma-Aldrich manufactures and distributes serum albumins purified from a variety of primary methods including the true Cohn fractionation method, modified ethanol fractionation methods, heat shock and chromatography. Additional purification steps may include crystallization or charcoal filtration.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

This product is part of the USP Biologics program.

USP issued SDS can be found here.

Sales restrictions may apply.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable