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1134357

USP

Cisplatin

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
cis-Diammineplatinum(II) dichloride, cis-Dichlorodiammine platinum(II), cis-Platinum(II) diammine dichloride, Cisplatin
Linear Formula:
Pt(NH3)2Cl2
CAS Number:
Molecular Weight:
300.05
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

cisplatin

manufacturer/tradename

USP

mp

270 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

N.N.Cl[Pt]Cl

InChI

1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2

InChI key

LXZZYRPGZAFOLE-UHFFFAOYSA-L

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This Item
C2210000BP809479306
vibrant-m

1134357

Cisplatin

vibrant-m

C2210000

Cisplatin

vibrant-m

BP809

Cisplatin

vibrant-m

479306

cis-Diamineplatinum(II) dichloride

format

neat

format

neat

format

neat

format

-

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

BP

manufacturer/tradename

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical

application(s)

-

API family

cisplatin

API family

cisplatin

API family

cisplatin

API family

-

mp

270 °C (lit.)

mp

270 °C (lit.)

mp

270 °C (lit.)

mp

270 °C (lit.)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cisplatin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard and system suitability solution for assay and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Cisplatin
  • Cisplatin for Injection
  • Carboplatin Injection

Biochem/physiol Actions

Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Sigma-Aldrich

Sigma-Aldrich

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Cisplatin
United States Pharmacopeia, 41(6), 1030-1030 (2020)
Carboplatin Injection
United States Pharmacopeia, 46(5) (2023)
Cisplatin for Injection
United States Pharmacopeia, 46(4) (2021)

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