1317007

Hydrocortisone acetate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Hydrocortisone 21-acetate, 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-acetate, 17-α-Hydroxycorticosterone acetate, 17-Hydroxycorticosterone 21-acetate, 21-Acetoxy-4-pregnene-11β,17α-diol-3,20-dione, 4-Pregnene-11β,17α,21-triol-3,20-dione 21-acetate
• Empirical Formula (Hill Notation): C₂₃H₃₂O₆
• CAS Number: 50-03-3
• Molecular Weight: 404.50
• Beilstein/REAXYS Number: 2066841
• MDL number: MFCD00037714
• UNSPSC Code: 41116107
• PubChem Substance ID: 329750076
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: hydrocortisone
• manufacturer/tradename: USP
• mp: 223 °C (dec.) (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1
• InChI key: ALEXXDVDDISNDU-JZYPGELDSA-N
• Gene Information: human ... NR3C1(2908)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hydrocortisone acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

• Hydrocortisone Acetate Cream
• Hydrocortisone Acetate Lotion
• Hydrocortisone Acetate Ointment
• Neomycin Sulfate and Hydrocortisone Acetate Ointment
• Neomycin Sulfate and Hydrocortisone Acetate Ophthalmic Suspension
• Oxytetracycline Hydrochloride and Hydrocortisone Acetate Ophthalmic Suspension
• Neomycin and Polymyxin B Sulfates and Hydrocortisone Acetate Cream

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H360Df,H373
• pcodes: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B - STOT RE 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable