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MilliporeSigma

1380105

USP

Melatonin

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

N-Acetyl-5-methoxytryptamine

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About This Item

Empirical Formula (Hill Notation):
C13H16N2O2
CAS Number:
73-31-4
Molecular Weight:
232.28
Beilstein/REAXYS Number:
205542
MDL number:
MFCD00005655
UNSPSC Code:
41116107
PubChem Substance ID:
329750346
NACRES:
NA.24

Key Documents

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grade

pharmaceutical primary standard

API family

melatonin

manufacturer/tradename

USP

mp

116.5-118 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

COc1ccc2[nH]cc(CCNC(C)=O)c2c1

InChI

1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)

InChI key

DRLFMBDRBRZALE-UHFFFAOYSA-N

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1 of 4

This Item
PHL223304443008.14537
Melatonin United States Pharmacopeia (USP) Reference Standard

USP

1380105

Melatonin

Melatonin phyproof® Reference Substance

PHL22330

Melatonin

Melatonin A hormone that has been postulated as the mediator of photo-induced anti-gonadotropic activity in photoperiodic mammals.

Sigma-Aldrich

444300

Melatonin

Melatonine for synthesis

Sigma-Aldrich

8.14537

Melatonine

manufacturer/tradename

USP

manufacturer/tradename

PhytoLab

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

grade

pharmaceutical primary standard

grade

primary reference standard

grade

-

grade

-

application(s)

pharmaceutical (small molecule)

application(s)

food and beverages
pharmaceutical

application(s)

-

application(s)

-

format

neat

format

neat

format

-

format

-

API family

melatonin

API family

-

API family

-

API family

-

mp

116.5-118 °C (lit.)

mp

116.5-118 °C (lit.)

mp

-

mp

116-118 °C

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Melatonin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard and system suitability solutions for assay, performance tests, strength, and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Melatonin Tablets [1]
  • Melatonin [2]

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Melatonin
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(4), 5143-5143 (2020)
Melatonin Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(6), 5144-5144 (2013)
Ismail Gögenur et al.
Journal of pineal research, 57(1), 10-15 (2014-04-09)
The aim was to examine the effect of perioperative melatonin treatment on clinical cardiac morbidity and markers of myocardial ischemia in patients undergoing elective surgery for abdominal aortic aneurism. Reperfusion injury results in increased cardiac morbidity in patients undergoing surgery
Reuben K Wong et al.
Digestive diseases and sciences, 60(1), 186-194 (2014-08-06)
Probiotics have treatment efficacy in irritable bowel syndrome (IBS), but the exact mechanism remains obscure. One hypothesis is the mediation of melatonin levels, leading to changes in IBS symptoms. The purpose of this study was to evaluate the effects of
Juan R Calvo et al.
Journal of pineal research, 55(2), 103-120 (2013-07-31)
Melatonin is the major secretory product synthesized and secreted by the pineal gland and shows both a wide distribution within phylogenetically distant organisms from bacteria to humans and a great functional versatility. In recent years, a considerable amount of experimental
View All Related Papers

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