1463304

USP

Nicotine bitartrate dihydrate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):
(−)-Nicotine hydrogen tartrate salt dihydrate
Empirical Formula (Hill Notation):
C10H14N2 · 2C4H6O6 · 2H2O
CAS Number:
Molecular Weight:
498.44
NACRES:
NA.24

grade

pharmaceutical primary standard

manufacturer/tradename

USP

Featured Industry

Pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C17H15ClN2O3/c1-9(2)16(22)19-11-4-5-14(21)12(8-11)17-20-13-7-10(18)3-6-15(13)23-17/h3-9,20H,1-2H3,(H,19,22)/b17-12-

InChI key

YGMGVHYZWYRTJJ-ATVHPVEESA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.
Sales restrictions may apply.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Statements

RIDADR

UN 1659 6.1 / PGII

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Cheng Xiao et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(9), 3734-3746 (2015-03-06)
The glutamatergic subthalamic nucleus (STN) exerts control over motor output through nuclei of the basal ganglia. High-frequency electrical stimuli in the STN effectively alleviate motor symptoms in movement disorders, and cholinergic stimulation boosts this effect. To gain knowledge about the...
Brandon J Henderson et al.
The Journal of general physiology, 143(1), 51-66 (2014-01-01)
Chronic exposure to nicotine up-regulates high sensitivity nicotinic acetylcholine receptors (nAChRs) in the brain. This up-regulation partially underlies addiction and may also contribute to protection against Parkinson's disease. nAChRs containing the α6 subunit (α6* nAChRs) are expressed in neurons in...

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