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1602502

USP

Retinyl palmitate

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
Vitamin A palmitate, all−trans−Retinol palmitate
Empirical Formula (Hill Notation):
C36H60O2
CAS Number:
Molecular Weight:
524.86
Beilstein/REAXYS Number:
1917366
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

retinyl compounds

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(CCCCCCCCCCCCCCC)=O)C(C)(C)CCC1

InChI

1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+

InChI key

VYGQUTWHTHXGQB-FFHKNEKCSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Application


  • Retinyl palmitate in nanoemulgels for skin diseases: Research explores the application of retinyl palmitate in innovative nanoemulgels, demonstrating its efficacy in treating skin conditions through enhanced delivery mechanisms. This aligns with its use in skin rejuvenation and anti-aging treatments, providing a novel approach for topical therapy (Sghier et al., 2024).

  • Stability and efficacy in UVB-induced skin photoaging: A study assessed retinyl palmitate′s efficacy against UVB-induced photoaging, showing significant protective effects on the skin. This underscores its potential as a high-purity biochemical assay component for studying retinoid signaling and its impact on skin health (Shu et al., 2023).

  • Enhanced anti-photoaging therapy: Comparative research among various retinoids, including retinyl palmitate, highlights its superior anti-inflammatory and antioxidative activities, positioning it as a preferred choice for anti-photoaging treatments. The study emphasizes its application in biochemical assays and as a vitamin A source in tissue engineering (Shu et al., 2023).

Biochem/physiol Actions

Review: Vitamin A metabolism.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Health hazard

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Repr. 1B

wgk_germany

WGK 2

flash_point_f

381.2 °F

flash_point_c

194.00 °C


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Elevated nonfasting TG-rich lipoprotein levels are a risk factor for CVD. To further evaluate the relevance of LDL-receptor (LDLr) pathway and heparan sulfate proteoglycans (HSPGs) in TG homeostasis, we analyzed fasting and postprandial TG levels in mice bearing combined heterozygous
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