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1612517

USP

Sertraline hydrochloride racemic mixture

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
(±)-Sertraline hydrochloride, 1R,4R)-rel-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride
Empirical Formula (Hill Notation):
C17H17Cl2N · HCl
CAS Number:
Molecular Weight:
342.69
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

sertraline

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl.CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c3ccccc13

InChI

1S/C17H17Cl2N.ClH/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11;/h2-6,8,10,12,17,20H,7,9H2,1H3;1H/t12-,17-;/m0./s1

InChI key

BLFQGGGGFNSJKA-XHXSRVRCSA-N

Gene Information

human ... SLC6A4(6532)

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This Item
1612539Y0000828Y0000866
Sertraline hydrochloride United States Pharmacopeia (USP) Reference Standard

1612539

Sertraline hydrochloride

Sertraline hydrochloride European Pharmacopoeia (EP) Reference Standard

Y0000828

Sertraline hydrochloride

manufacturer/tradename

USP

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

EDQM

format

neat

format

neat

format

neat

format

neat

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

API family

sertraline

API family

sertraline

API family

sertraline

API family

sertraline

Gene Information

human ... SLC6A4(6532)

Gene Information

human ... SLC6A4(6532)

Gene Information

human ... SLC6A4(6532)

Gene Information

human ... SLC6A4(6532)

General description

Sertraline hydrochloride is a SSRI i.e selective serotonin reuptake inhibitor. It is mainly used in treating psychiatric disorders. It also is effective in treating hypotension occurring in disorders like neurocardiogenic syncope and idiopathic orthostatic hypotension which is affected by autonomic dysfunction.

Application

Sertraline hydrochloride racemic mixture USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Sertraline Hydrochloride Tablets
  • Sertraline Hydrochloride

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Effect of sertraline hydrochloride on dialysis hypotension.
Dheenan S
American Journal of Kidney Diseases, 31(4), 624-630 (1998)
Aquatic ecotoxicity of the selective serotonin reuptake inhibitor sertraline hydrochloride in a battery of freshwater test species.
Minagh E
Ecotox. Environ. Safety, 72(2), 434-440 (2009)
Nachshon Korem et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 39(12), 2709-2722 (2014-06-06)
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