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1623626

USP

Sucralose

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside, E955, Trichlorosucrose

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400 MG

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About This Item

Empirical Formula (Hill Notation):
C12H19Cl3O8
CAS Number:
56038-13-2
Molecular Weight:
397.63
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329751159
MDL number:
MFCD03648615
Beilstein/REAXYS Number:
3654410

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Product Name

Sucralose, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1

SMILES string

OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl

InChI key

BAQAVOSOZGMPRM-QBMZZYIRSA-N

grade

pharmaceutical primary standard

API family

sucralose

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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PHR13421.008951.00894
Sucralose United States Pharmacopeia (USP) Reference Standard

USP

1623626

Sucralose

Sucralose Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1342

Sucralose

Sucralose granular, EMPROVE® ESSENTIAL, Ph. Eur., ChP, JPE, NF

SAFC

1.00895

Sucralose

Sucralose powder, EMPROVE® ESSENTIAL, Ph. Eur., ChP, JPE, NF

SAFC

1.00894

Sucralose

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

-

manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

-

format

neat

format

neat

format

-

format

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

liquid formulation
pharmaceutical
solid formulation

application(s)

liquid formulation
pharmaceutical
solid formulation

API family

sucralose

API family

sucralose

API family

-

API family

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

15-25°C

storage temp.

15-25°C

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Sucralose USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

A synthetic sweet tastant detectable by humans. Activates T1R2/T1R3 sweet taste receptors on enteroendocrine cells and elicits increased hormonal secretion of glucagon-like peptide-1 and glucose-dependent insulinotrophic peptide.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

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Product No.
Description
Pricing

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Sucralose--an overview of the toxicity data.
H C Grice et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 38 Suppl 2, S1-S6 (2000-07-07)
Susan S Schiffman et al.
Journal of toxicology and environmental health. Part B, Critical reviews, 16(7), 399-451 (2013-11-14)
Sucralose is a synthetic organochlorine sweetener (OC) that is a common ingredient in the world's food supply. Sucralose interacts with chemosensors in the alimentary tract that play a role in sweet taste sensation and hormone secretion. In rats, sucralose ingestion
Knut Erik Tollefsen et al.
The Science of the total environment, 438, 510-516 (2012-10-04)
Sucralose (1,6-dichloro-1,6-dideoxy-b-D-fructo-furanosyl 4-chloro-4-deoxy-a-D-galactopyranoside), sold under the trade name Splenda, has been detected in municipal effluents and surface waters in the United States and Europe. The environmental presence of sucralose has led to interest in the possibility of toxic effects in
V Lee Grotz et al.
Regulatory toxicology and pharmacology : RTP, 55(1), 1-5 (2009-05-26)
Sucralose is a non-nutritive sweetener used in a broad range of foods and beverages and is the non-nutritive sweetener in retail SPLENDA Sweetening Products, composed of sucralose and common food ingredients. A review of the extensive body of evidence that
I Knight
Canadian journal of physiology and pharmacology, 72(4), 435-439 (1994-04-01)
Sucralose is a new sweetener discovered during a collaborative research program between Tate & Lyle and Queen Elizabeth College of the University of London. It is made by selective substitution of sucrose hydroxyl groups by chlorine, resulting in a highly
View All Related Papers

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