1710006

Vanillin

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 4-Hydroxy-3-methoxybenzaldehyde, Vanillic aldehyde
• Linear Formula: 4-(HO)C₆H₃-3-(OCH₃)CHO
• CAS Number: 121-33-5
• Molecular Weight: 152.15
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329751485
• MDL number: MFCD00006942
• Beilstein/REAXYS Number: 472792

Properties

• InChI key: MWOOGOJBHIARFG-UHFFFAOYSA-N
• InChI: 1S/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,10H,1H3
• grade: pharmaceutical primary standard
• vapor density: 5.3 (vs air)
• vapor pressure: >0.01 mmHg ( 25 °C)
• API family: vanillin
• form: crystalline powder
• manufacturer/tradename: USP
• bp: 170 °C/15 mmHg (lit.)
• application(s): USP Biologics; pharmaceutical (small molecule)
• format: neat

Description

General description

Vanillin, a phenolic aldehyde, finds its use in microbiological applications, particularly in the formulation of biologic products where flavoring or masking agents are required. While its primary role in biologics is minimal, it serves as an excipient to improve the palatability of oral biologic formulations. Vanillin′s safety profile ensures its suitability for inclusion in biologic products designed for human consumption.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

It has been used as reference standard in calibrating hot stage; during thermomicroscopic investigation performed with optical polarizing microscope; usually equipped with a hot stage and temperature controller.[1]

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

This product is part of USP Biologics Program.

Vanillin is an aromatic compound, and is used for flavoring foods. It is has biogenetic relationship to phenylpropanoid pathway.[2] It is mostly used in foods, beverages, perfumes and pharmaceuticals.[3]

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: 319.6 - 321.4 °F - closed cup
• flash_point_c: 159.8 - 160.8 °C - closed cup