Gas Chromatography (GC) Solvents
Gas chromatography (GC) is an analytical technique used to separate and analyze compounds that can be vaporized without decomposition. The process begins with injecting a sample into a chromatograph, where an inert gas (the mobile phase) carries it through a column. Inside the column, the sample components interact with a stationary phase, allowing for separation. The compounds are then detected using instruments such as a flame ionization detector (FID) or a mass spectrometer (MS).
GC analysis involves sample preparation, including the extraction and concentration of extracts before injection. This process requires solvents of the highest purity to ensure accurate results. SupraSolv® solvents are specifically designed for sensitive detection in residue and environmental analysis. Their exceptional purity minimizes background interference and enhances the signal-to-noise ratio, leading to a low baseline in GC analysis. With an extended retention time range, minimal contaminants, and consistent batch-to-batch quality, these solvents ensure reliable analytical results. This consistency reduces the need for costly purification and repeated analysis, improving efficiency and cost-effectiveness. We offer GC solvents tailored to specific applications and detection methods.
Products
Ethyl acetate
suitable for HPLC, ≥99.7%
Acetone
HPLC Plus, for HPLC, GC, and residue analysis, ≥99.9%
Dichloromethane
HPLC Plus, for HPLC, GC, and residue analysis, ≥99.9%, contains 50-150 ppm amylene as stabilizer
Chloroform
HPLC Plus, for HPLC, GC, and residue analysis, ≥99.9%, contains amylenes as stabilizer
Ethyl acetate
HPLC Plus, for HPLC, GC, and residue analysis, 99.9%
Hexane
≥99%, suitable for GC/MS, suitable for EPA 1613, ReagentPlus®
Toluene
HPLC Plus, for HPLC, GC, and residue analysis, ≥99.9%
Dichloromethane
anhydrous, ≥99.8%, contains 40-150 ppm amylene as stabilizer
2-Propanol
99.9%, HPLC Plus, for residue analysis, suitable for gas chromatography (GC), HPLC, suitable for ASTM® 7979 and ASTM® 7968
tert-Butyl methyl ether
HPLC Plus, for HPLC, GC, and residue analysis, 99.9%
Dimethyl sulfoxide
puriss. p.a., ACS reagent, ≥99.9% (GC)
o-Xylene
puriss. p.a., ≥99.0% (GC)
Hexane
≥99% (GC), ACS reagent, puriss. p.a., reag. Ph. Eur.
Diisopropyl ether
puriss. p.a., ≥98.5% (GC)
Acetonitrile
≥99.9% (GC), gradient grade, gas chromatography (GC), HPLC, OmniSolv®
Hexane
≥95%, HPLC Plus, for residue analysis, suitable for gas chromatography (GC) and HPLC, suitable for EPA 1613, EPA ACB B21-02, EPA OTM-45, and EPA ACB B23-05b
Hexane
≥98% (GC), suitable for gas chromatography (GC) ECD and FID, SupraSolv®
N,N-Dimethylacetamide
puriss. p.a., ≥99.5% (GC)
Triethanolamine
≥99.0% (GC)
2-Propanol
≥99.8% (GC), ACS reagent, reag. Ph. Eur., USP/NF, reag. ISO
SupraSolv® GC Solvents Specifications
Our GC solvent qualities are ideal for all gas chromatography applications. High purity is provided by specially designed production processes for accurate, reliable and reproducible analytical results.
SupraSolv® for ECD and FID
SupraSolv® solvents are specifically designed for gas chromatography applications, particularly for Electron Capture Detection (ECD) and Flame Ionization Detection (FID). Their production process includes glass distillation, which minimizes impurities and results in extremely low levels of non-volatile matter and residue. This high level of purity enhances the reliability of analytical results and significantly extends the lifespan of gas chromatography columns. By reducing contaminants that contribute to column degradation, SupraSolv® solvents help maintain the integrity of the analytical process, ensuring consistent performance over time. These high-purity, glass-distilled solvents meet the stringent requirements of EPA Method 508, delivering outstanding quality and reliability for analytical applications.
SupraSolv® solvents offer exceptional sensitivity, with a detection limit of 3 pg/mL (compared to Lindane) for GC-ECD and ≤ 3 ng/mL (compared to n-Tetradecane) for GC-FID. These solvents are specifically optimized for:
- Analyzing pesticides in fruits and vegetables
- Detecting acrylamide in food
- Measuring polychlorinated biphenyls (PCBs) in water and sludge
- Assessing DDT (a preservative and insecticide) in milk, fish, meat, and fruits
- Analyzing highly volatile halogenated hydrocarbons in water and nitrates in lettuce and radishes
- Detecting BTX (Benzene, Toluene, Xylene)
- Analyzing hydrocarbon oil indices in water
- Determining emissions from car cockpit materials
SupraSolv® GC-MS
SupraSolv® solvents are used in gas chromatography-mass spectrometry applications, delivering exceptional performance through stringent purification processes. With a detection limit of ≤ 3 ng/mL (compared to n-Tetradecane) for GC-MS, these solvents meet the high demands of analytical laboratories, ensuring accurate and reliable results.
They are utilized for a variety of applications, including analyzing dioxins and furans (PCDD/PCDF) in meat, fish, and milk, detecting polycyclic aromatic hydrocarbons (PAHs) in vegetables, olive oil, and meat; conducting pesticide analysis in fruits and vegetables; determining drugs in human hair; and analyzing phthalates in child-care products and toys.
SupraSolv® Hypergrade for Organic Trace Analysis
SupraSolv® hypergrade is specifically designed for the analysis of organic trace elements, offering stringent specifications that include ≤ 1 ng/mL (compared to Tetrachloromethane) using GC-ECD, ≤ 2 pg/mL for Lindane with GC-ECD, and ≤ 2 ng/mL for both n-Tetradecane using GC-FID and GC-MS. This solvent ensures unparalleled sensitivity and accuracy in analytical applications. Its narrow specification range enables the detection of low boiling substances with remarkable reliability, which is crucial for applications in pesticide and organic residue analysis.
SupraSolv® Headspace for Analysis of Residual Solvents
Headspace gas chromatography is a critical technique for analyzing residual solvents in drug substances, excipients, and drug products, in accordance with ICH, Ph Eur, and USP guidelines. SupraSolv® Headspace solvents meet stringent purity standards, with class 1 solvents at ≤ 1 µg/g, class 2 solvents at ≤ 10 µg/g, and class 3 solvents at ≤ 50 µg/g, ensuring compliance with regulatory standards while delivering reliable analytical results.
SupraSolv® Headspace are free from contaminants that could coelute with peaks of interest in the sample, ensuring accurate and precise results. Furthermore, they undergo microfiltration to 0.2 μm, effectively removing any particulate matter that could compromise the integrity of the analysis. Packaged under inert gas, these solvents have an extended shelf life, maintaining their quality and performance over time.
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