Organotin reagents are pivotal in progressing organic synthesis in the quest for synthesizing highly complex natural compounds and creating new chemical structures and known bond formations. Organotin compounds, also known as stannanes, have at least one tin-carbon bond and are frequently utilized synthons in palladium-catalyzed cross coupling reactions. Since the first report by Stille in 1977, numerous applications of organotin reagents have become commonplace in the formation of new carbon-carbon (C-C) bonds for the synthesis of natural products and other small molecules for drug discovery.
Organotin chemistry continues to be an active field of research in organometallic chemistry and has a wide range of pharmacological, agrochemical, and polymerization applications. Our organotin reagents are used for the generation of Stille Coupling precursors to obtain more complex coupling partners and dehalogenation reactions to afford hydrocarbons in late-stage synthetic sequences.
Our extensive portfolio of organotin compounds includes:
We also offer other organometallic reagents to facilitate cross-coupling reactions and the discovery of new bond-forming methodologies. To view these reagents, visit our Organolithium, Organozinc, Organoaluminum, and Organosilicon reagents pages.