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Showing 1-10 of 10 results for "05-517" within Papers
Nathalie Alekos et al.
JCI insight (2023-02-03)
The energetic costs of bone formation require osteoblasts to coordinate their activities with tissues, like adipose, that can supply energy-dense macronutrients. In the case of intermittent parathyroid hormone treatment (PTH), a strategy used to reduce fracture risk, bone formation is
Joachim Albers et al.
The Journal of cell biology, 192(6), 1057-1072 (2011-03-16)
Although Wnt signaling in osteoblasts is of critical importance for the regulation of bone remodeling, it is not yet known which specific Wnt receptors of the Frizzled family are functionally relevant in this process. In this paper, we show that
Cell-specific effects of nitric oxide deficiency on parathyroid hormone-related peptide (PTHrP) responsiveness and PTH1 receptor expression in cardiovascular cells.
Rolf Schreckenberg, Sibylle Wenzel, Rui Manuel da Costa Rebelo, Anja Rothig, Rainer Meyer et al.
Endocrinology null
Altered ovarian function affects skeletal homeostasis independent of the action of follicle-stimulating hormone.
Gao, J; Tiwari-Pandey, R; Samadfam, R; Yang, Y; Miao, D; Karaplis, AC; Sairam, MR; Goltzman, D
Endocrinology null
Kimberly J Curtis et al.
Journal of the Royal Society, Interface, 17(173), 20200568-20200568 (2020-12-17)
Most patients who succumb to cancer have metastases to bone that contribute to their death. Cancer cells that metastasize to bone are regularly subjected to mechanical stimuli that may affect their proliferation, growth and protein expression. Understanding why some cancer
Anja Röthig et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 29(3-4), 485-492 (2012-04-18)
The study was aimed to investigate whether nicotine affects endothelial expression of PTHrP and PTHrP receptor, a peptide system involved in endothelial protection against apoptosis. Isolated and cultured rat coronary endothelial cells were used. Immunoblot techniques were used to study
Christine V Marzan et al.
Developmental biology, 349(2), 125-136 (2010-10-27)
We generated a transgenic (Tg)-mouse model expressing a dominant negative-(DN)-RARα, (RARαG303E) under adipocytes-specific promoter to explore the paracrine role of adipocyte retinoic acid receptors (RARs) in mammary morphogenesis. Transgenic adipocytes had reduced level of RARα, β and γ, which coincided
Ruinan Lu et al.
PloS one, 9(4), e93864-e93864 (2014-04-08)
The epigenetic regulator Bmi1 is key in haematopoietic stem cells, and its inactivation leads to defects in haematopoiesis. Parathyroid hormone (PTH), an important modulator of bone homeostasis, also regulates haematopoiesis, so we asked whether PTH administration improves bone marrow microenvironment
Qi Zhu et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 28(9), 1898-1911 (2013-05-30)
To assess the effect of hypoparathyroidism on osteogenesis and bone turnover in vivo, bone marrow ablation (BMXs) were performed in tibias of 8-week-old wild-type and parathyroid hormone-null (PTH(-/-)) mice and newly formed bone tissue was analyzed from 5 days to
Hara Levy et al.
The Journal of allergy and clinical immunology, 115(2), 252-258 (2005-02-08)
Defensins are antimicrobial peptides that may take part in airway inflammation and hyperresponsiveness. We characterized the genetic diversity in the defensin beta-1 (DEFB1) locus and tested for an association between common genetic variants and asthma diagnosis. To identify single nucleotide
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