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07-307
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Showing 1-20 of 20 results for "07-307" within Papers
Journal of virology, 88(18), 10792-10802 (2014-07-11)
Bluetongue virus (BTV) is a double-stranded RNA (dsRNA) virus that causes an economically important disease in ruminants. BTV infection is a strong inducer of type I interferon (IFN-I) in multiple cell types. It has been shown recently that BTV and
Virus research, 180, 49-58 (2014-01-01)
Herpes simplex virus type 1 (HSV-1) causes a lytic infection in epithelial cells before being captured and moved via retrograde axonal transport to the nuclei of the sensory neurons of the trigeminal ganglion or dorsal root, where it establishes a
The Journal of general virology, 88(Pt 3), 956-966 (2007-02-28)
Mapuera virus (MPRV) is a paramyxovirus that was originally isolated from bats, but its host range remains unknown. It was classified as a member of the genus Rubulavirus on the basis of structural and genetic features. Like other rubulaviruses it
Cellular microbiology, 7(12), 1749-1762 (2005-11-29)
In vivo studies with the mouse-specific member of the attaching and effacing (A/E) family of pathogens raised the possibility that these non-invasive enteric pathogens can specifically inhibit inducible nitric oxide synthase (iNOS) expression to prevent the production of antimicrobial nitric
Viruses, 10(12) (2018-12-21)
Hepatitis E virus (HEV) is responsible for large waterborne epidemics of hepatitis in endemic countries and is an emerging zoonotic pathogen worldwide. In endemic regions, HEV-1 or HEV-2 genotypes are frequently associated with fulminant hepatitis in pregnant women, while with
Basal expression levels of IFNAR and Jak-STAT components are determinants of cell-type-specific differences in cardiac antiviral responses.
Journal of virology null
International journal of cancer, 126(4), 896-908 (2009-08-05)
The development of autochtonous mammary tumors in HER-2/neu transgenic mice is facilitated by immune tolerance to the neu-transgene. However, appropriate vaccination strategies can initiate immune system-mediated antitumor response by a process that requires IFN-gamma. We investigated the role of inducible
PLoS pathogens, 7(10), e1002292-e1002292 (2011-10-15)
Gammaherpesviruses such as KSHV and EBV establish lifelong persistent infections through latency in lymphocytes. These viruses have evolved several strategies to counteract the various components of the innate and adaptive immune systems. We conducted an unbiased screen using the genetically
Virology journal, 9, 213-213 (2012-09-21)
Chikungunya virus (CHIKV) is an arthritogenic member of the Alphavirus genus (family Togaviridae) transmitted by Aedes mosquitoes. CHIKV is now known to target non hematopoietic cells such as epithelial, endothelial cells, fibroblasts and to less extent monocytes/macrophages. The type I
Hepatitis C virus core protein differently regulates the JAK-STAT signaling pathway under interleukin-6 and interferon-gamma stimuli.
The Journal of Biological Chemistry, 278, 28562-28571 (2003)
Precision-cut slice cultures of tumors from MMTV-neu mice for the study of the ex vivo response to cytokines and cytotoxic drugs.
In Vitro Cellular & Developmental Biology. Animal null
Porcine reproductive and respiratory syndrome virus Nsp1? inhibits interferon-activated JAK/STAT signal transduction by inducing karyopherin-?1 degradation.
Journal of virology, 87, 5219-5228 (2013)
Donor T-cell alloreactivity against host thymic epithelium limits T-cell development after bone marrow transplantation.
Blood null
Journal of immunology (Baltimore, Md. : 1950), 181(10), 7284-7291 (2008-11-05)
Tissue response to injury includes expression of genes encoding cytokines and chemokines. These regulate entry of immune cells to the injured tissue. The synthesis of many cytokines and chemokines involves NF-kappaB and signal transducers and activators of transcription (STAT). Injury
Nature, 377(6550), 591-594 (1995-10-19)
Many cell functions are regulated by members of the cytokine receptor superfamily. Signalling by these receptors depends upon their association with Janus kinases (JAKs), which couple ligand binding to tyrosine phosphorylation of signalling proteins recruited to the receptor complex. Among
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 23(8), 413-421 (2003-09-19)
Interferon-gamma (IFN-gamma)-induced indoleamine 2,3-dioxygenase (IDO) activity inhibits the growth of susceptible intracellular pathogens by catalyzing the oxidative cleavage of the indole ring of L-tryptophan and depleting pools of the essential amino acid. Tumor necrosis factor-alpha (TNF-alpha) synergistically enhances the IDO
STAT2 deficiency and susceptibility to viral illness in humans.
Proceedings of the National Academy of Sciences of the USA null
Induction of type I interferons by a novel porcine reproductive and respiratory syndrome virus isolate.
Virology, 432, 261-270 (2012)
Gut, 71(5), 991-1005 (2021-05-23)
RNA helicase DDX5 is downregulated during HBV replication and poor prognosis HBV-related hepatocellular carcinoma (HCC). The objective of this study is to investigate the role of DDX5 in interferon (IFN) signalling. We provide evidence of a novel mechanism involving DDX5
BMC cancer, 14, 257-257 (2014-04-15)
STAT1 has been attributed a function as tumor suppressor. However, in breast cancer data from microarray analysis indicated a predictive value of high mRNA expression levels of STAT1 and STAT1 target genes belonging to the interferon-related signature for a poor
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