Showing 1-20 of 20 results for "102-32-9"
Zhenwen Chen et al.
European journal of clinical investigation, 42(3), 310-320 (2011-09-02)
Topoisomerase IIα (topo IIα) protein expression has prognostic significance in many cancers. However, it is still unclear whether topo IIα protein expression and gene alterations play roles as prognostic factors in diffuse large B-cell lymphoma (DLBCL). We selected 102 patients...
Yongmei Chen et al.
Frontiers in bioscience : a journal and virtual library, 11, 3121-3128 (2006-05-25)
Brain arteriovenous malformations (BAVM) have high matrix metalloproteinase-9 (MMP-9) expression, the source of which is unclear. We hypothesized MMP-9 production might be due to inflammation in BAVM. Compared to control brain tissues (n = 5), BAVM tissue (n = 139)...
Qing-Wen Shan et al.
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 12(4), 262-266 (2010-04-27)
To investigate the relationship of the promoter of matrix metalloproteinase-9 (MMP-9) gene polymorphisms with the susceptibility and clinical features of Helicobacter pylori (H. pylori)-related chronic gastritis and duodenal ulcer in children. One hundred children with chronic gastritis, 32 children with...
Jun Chen et al.
International journal of pharmaceutics, 340(1-2), 29-33 (2007-04-21)
Pharmacokinetics and lactone/carboxylate equilibrium of 9-Nitrocamptothecin (9-NC) were compared after intravenous (i.v.) and intramuscular (i.m.) injection at a dose of 1.5mg/kg 9-NC solution. The concentrations of three different forms of 9-NC, namely lactone, carboxylate and total 9-NC, were measured by...
Silvio Roncella et al.
Diagnostic molecular pathology : the American journal of surgical pathology, part B, 17(1), 28-33 (2008-02-28)
The present study investigates the diagnostic significance of human mammaglobin (hMAM) mRNA expression in pleural effusions (PE) from breast cancer (BC) patients. Two hundred and fifty PE samples, including 32 from patients who had diagnosis of BC, 116 from patients...
Frank J Quayle et al.
Surgery, 142(6), 800-805 (2007-12-08)
The occurrence of pheochromocytoma in multiple endocrine neoplasia type 2A (MEN 2A) carriers varies greatly. This study aims to determine PC expression for specific MEN 2A RET mutations. Charts of MEN 2A patients enrolled in our multiple endocrine neoplasia program...
Lluis Catasus et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 21(2), 131-139 (2007-12-18)
Mutations of the oncogene PIK3CA occur frequently in endometrial carcinomas, but their prognostic significance is unclear. To determine the clinicopathological and molecular implications of these mutations, PIK3CA status was investigated in 109 endometrial (102 endometrioid and 7 mixed) carcinomas and...
Laia Agell et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(3), 443-452 (2010-11-30)
The phosphatidylinositol 3-kinase (PI3K)-AKT and RAS-MAPK pathways are deregulated in a wide range of human cancers by gain or loss of function in several of their components. Our purpose has been to identify genetic alterations in members of these pathways...
Viralam S Kiran et al.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 13(18), e2124-e2129 (2017-07-26)
The aims of this study were to determine the incidence and correlates of left ventricular (LV) dysfunction amongst percutaneous patent ductus arteriosus (PDA) device closure patients, and to propose an indexed parameter for predicting LV dysfunction. In a retrospective cross-sectional...
Qaiser Bashir et al.
The Lancet. Haematology, 6(5), e266-e275 (2019-03-27)
Retrospective studies suggest that conditioning therapy with busulfan plus melphalan could result in longer progression-free survival compared with melphalan alone in patients with multiple myeloma undergoing autologous haemopoietic cell transplantation (auto-HCT). We aimed to test this hypothesis in a randomised...
Sara S Jarvis et al.
Frontiers in physiology, 5, 86-86 (2014-03-14)
Young black women have higher prevalence of hypertension during pregnancy compared to white women, which may be attributable to differences in blood pressure (BP) regulation. We hypothesized that young normotensive black women would demonstrate augmented muscle sympathetic nerve activity (MSNA)...
Basheer Peer Mohamed et al.
Developmental medicine and child neurology, 54(3), 274-277 (2012-01-25)
The aim of this study was to report a single-centre experience of flunarizine in childhood migraine with focus on safety and efficacy. We conducted a retrospective observational audit of 72 individuals (40 male, 32 female; mean age 13y; age range...
Kandoussi Nadia et al.
Gene, 568(1), 31-34 (2015-05-11)
There is increasing evidence for the effect of rs12979860 IL28B polymorphism in response to the standard treatment PEG-IFN/RBV (i.e. combination of pegylated interferon and ribavirin) in chronic hepatitis C virus (HCV) infection. The present study aimed to determine the impact...
Matilda Chelimo Saina et al.
PloS one, 10(8), e0137140-e0137140 (2015-09-01)
Disease progression varies among HIV-1-infected individuals. The present study aimed to explore possible viral and host factors affecting disease progression in HIV-1-infected children. Since 2000, 102 HIV-1 vertically-infected children have been followed-up in Kenya. Here we studied 29 children (15...
Gemma Sullivan et al.
Brain, behavior, and immunity, 90, 311-318 (2020-09-14)
Preterm birth is associated with dysconnectivity of structural brain networks, impaired cognition and psychiatric disease. Systemic inflammation contributes to cerebral dysconnectivity, but the immune mediators driving this association are poorly understood. We analysed information from placenta, umbilical cord and neonatal...
Toby A Eyre et al.
Transfusion, 54(5), 1231-1234 (2013-10-15)
Rarely, healthy donors fail adequate peripheral blood stem cell (PBSC) mobilization. If the recipient has already received conditioning chemotherapy, this can result in the donor undergoing urgent marrow harvest under general anesthesia. Plerixafor is a novel CXCR4 antagonist, licensed for...
Ming-Sheng Zhou et al.
American journal of physiology. Heart and circulatory physiology, 296(3), H833-H839 (2009-01-20)
Insulin activation of the phosphatidylinositol 3-kinase (PI3K) pathway stimulates glucose uptake in peripheral tissues and synthesis of nitric oxide (NO) in the endothelium. Insulin resistance (IR) and hypertension frequently coexist, particularly among individuals with salt-sensitive hypertension. The mechanisms underlying this...
Johan Stender et al.
Lancet (London, England), 384(9942), 514-522 (2014-04-22)
Bedside clinical examinations can have high rates of misdiagnosis of unresponsive wakefulness syndrome (vegetative state) or minimally conscious state. The diagnostic and prognostic usefulness of neuroimaging-based approaches has not been established in a clinical setting. We did a validation study...
K Rajender Reddy et al.
The Lancet. Infectious diseases, 15(1), 27-35 (2014-12-09)
We did a phase 3 study in previous non-responders with chronic hepatitis C virus (HCV) genotype 1 infection and compensated liver disease that related to the standard of care for these patients at the time this study was initiated. We...
Karen M Edmond et al.
Lancet (London, England), 385(9975), 1315-1323 (2014-12-17)
Results of randomised controlled trials of newborn (age 1-3 days) vitamin A supplementation have been inconclusive. The WHO is coordinating three large randomised trials in Ghana, India, and Tanzania (Neovita trials). We present the findings of the Neovita trial in...

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