Showing 1-30 of 74 results for "103-16-2"
Kalliopi Platoni et al.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology, 22(5), 1307-1313 (2017-11-15)
The purpose of the present study was the optimization of dose calculation for intracranial stereotactic radiosurgery. We evaluated the Singular Value Decomposition (SVD) analysis as a novel optimization technique. Our approach to dose distribution optimization was to recover estimates of...
A Marti et al.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 27(3), 385-388 (2003-03-12)
In recent years, several groups have reported dominant inheritance of obesity conferred by missense, nonsense and frameshift mutations in the melanocortin 4 receptor gene (MC4R). Hence, MC4R is involved in the most common monogenic form of human obesity described so...
Yong-mei Zhu et al.
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 28(6), 371-374 (2007-10-18)
To analyze the mutation of FLT3 internal tandem duplication (FLT3-ITD) in bone marrow cells from patients with newly-diagnosed acute promyelocytic leukemia (APL). The mutation of FLT3-ITD in bone marrow mononuclear cells (MNCs) from 103 APL patients were screened by polymerase...
Daniel Buxton et al.
American journal of clinical pathology, 131(4), 574-579 (2009-03-18)
Originally described as a diagnostically useful marker for Ewing sarcoma, CD99 immunoreactivity has also been documented in a variety of other tumors, including hematopoietic neoplasms. By using conventional paraffin immunoperoxidase staining and tissue microarrays, we retrospectively investigated CD99 expression in...
Ilona Kondratiuk et al.
PloS one, 10(5), e0128285-e0128285 (2015-05-29)
The goal of this study was to determine whether a substantial decrease in adult neurogenesis influences epileptogenesis evoked by the intra-amygdala injection of kainic acid (KA). Cyclin D2 knockout (cD2 KO) mice, which lack adult neurogenesis almost entirely, were used...
Huiying He et al.
The American journal of surgical pathology, 35(4), 608-614 (2011-03-09)
A diagnosis of "atypical glands suspicious for cancer" (ATYP) in prostate needle biopsy is associated with a 40% to 50% risk of finding prostate carcinoma (PCa) in subsequent biopsies. Many studies have attempted to identify clinical, histologic, or molecular characteristics...
Jasper V Been et al.
Neonatology, 97(3), 183-189 (2009-10-30)
Prenatal hypoxia is an important cause of intrauterine growth retardation that affects fetal lung maturation, although previous studies have rendered conflicting results. The fetal chicken model allows the study of the isolated effects of hypoxia during development. We hypothesized that...
Ana Emília M Roberto et al.
Microorganisms, 8(1) (2020-01-17)
Mass spectrometry by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) was used to identify and differentiate the pattern of susceptibility of clinical isolates of Candida parapsilosis complex. 17 C. parapsilosis sensu stricto, 2 C. orthopsilosis, and 1 C. metapsilosis strains were obtained...
Ira M Jacobson et al.
The New England journal of medicine, 368(20), 1867-1877 (2013-04-24)
Patients chronically infected with hepatitis C virus (HCV) genotype 2 or 3 for whom treatment with peginterferon is not an option, or who have not had a response to prior interferon treatment, currently have no approved treatment options. In phase...
Folakemi Abiodun Osundare et al.
Pathogens (Basel, Switzerland), 9(5) (2020-05-24)
Hepatitis E virus (HEV) infection is a major public health concern in low-income countries, yet incidence and prevalence estimates are often lacking. Serum (n = 653) and faecal (n = 150) samples were collected from apparently healthy individuals using convenience...
Mohammed Mohiuddin et al.
International journal of radiation oncology, biology, physics, 86(3), 523-528 (2013-04-03)
To assess the efficacy of 2 different approaches to neoadjuvant chemoradiation for distal rectal cancers. One hundred six patients with T3/T4 distal rectal cancers were randomized in a phase 2 study. Patients received either continuous venous infusion (CVI) of 5-Fluorouracil...
Felicetta D'Amato et al.
Comparative immunology, microbiology and infectious diseases, 37(5-6), 281-288 (2014-09-25)
Coxiella burnetii is a pathogen causing Q fever. The aim of our work was to study Z3055, a strain that is genotypically related to the strain causing the Netherlands outbreak. We compared Z3055 to 5 other completed genomes available in...
Seyed Mohammad Bagher Hashemi-Soteh et al.
Genetic testing and molecular biomarkers, 16(7), 817-821 (2012-02-01)
Cytochrome P450 2C9 (CYP2C9) is a polymorphic enzyme responsible for the metabolism of different drugs, some with low therapeutic index. The frequency of functionally important mutations and alleles of the gene coding for CYP2C9 shows wide ethnic variations. The present...
Xiao-Yan Qiu et al.
European journal of clinical pharmacology, 64(11), 1069-1084 (2008-07-19)
The objective of this study was to retrospectively evaluate the effects of MDR1, CYP3A4*18B, and CYP3A5*3 genetic polymorphisms on cyclosporine A (CsA) pharmacokinetics in Chinese renal transplant patients during the first month after transplantation. A total of 103 renal transplant...
Eric M Snyder et al.
The Journal of physiology, 571(Pt 1), 121-130 (2005-12-13)
In humans, subjects homozygous for arginine (ArgArg) at codon 16 of the beta2-adrenergic receptor (beta2AR) have been shown to have greater agonist-mediated desensitization than subjects homozygous for glycine (GlyGly). We sought to determine if this substitution differentially influenced cardiovascular function...
Ivan Matic et al.
Molecular cell, 39(4), 641-652 (2010-08-28)
Reversible protein modification by small ubiquitin-like modifiers (SUMOs) is critical for eukaryotic life. Mass spectrometry-based proteomics has proven effective at identifying hundreds of potential SUMO target proteins. However, direct identification of SUMO acceptor lysines in complex samples by mass spectrometry...
Rachel D Schrier et al.
PloS one, 10(2), e0116526-e0116526 (2015-02-27)
HIV associated neurocognitive disorders (HAND) continue to affect cognition and everyday functioning despite anti-retroviral treatment (ART). Previous studies focused on mechanisms related to monocyte/macrophage mediated inflammation. However, in the ART era, there is increasing evidence for the involvement of CD8+...
Vanessa Lalonde-Robert et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 51(4), 464-468 (2012-10-10)
We evaluated the anesthetic efficacy of MS222 (dose, 1 or 2 g/L; pH 7) administered as an immersion bath (duration, 20 min) for nonbreeding female Xenopus leavis frogs (n = 33; average body weight, 103 ± 16 g). The acid...
Yolanda Picó et al.
Analytical and bioanalytical chemistry, 407(15), 4247-4259 (2015-01-31)
The accurate determination of perfluoroalkyl substances (PFSAs) in water, sediment, fish, meat, and human milk was achieved by ultrahigh-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-QqTOF-MS) with an ABSciex Triple TOF®. A group of 21 PFSAs was selected as target to...
Ahmet Sen et al.
Aviation, space, and environmental medicine, 78(5), 514-522 (2007-06-02)
First-generation H1-receptor antagonists are popularly used for alleviating allergy and cold symptoms, but these antihistaminics cause drowsiness and sedation. Such side effects could impair performance and, thus, could be the cause or a factor in accidents. Therefore, the prevalence of...
Ching-Hua Hsieh et al.
Journal of biomedical science, 19, 69-69 (2012-08-02)
Lipopolysaccharide (LPS) is recognized as the most potent microbial mediator presaging the threat of invasion of Gram-negative bacteria that implicated in the pathogenesis of sepsis and septic shock. This study was designed to examine the microRNA (miRNA) expression in whole...
I Kalina et al.
Teratogenesis, carcinogenesis, and mutagenesis, 11(2), 77-82 (1991-01-01)
The ability of polychlorinated biphenyls (PCBs) to induce chromosome aberrations and sister chromatid exchanges (SCE) in peripheral lymphocytes was studied in a group of workers occupationally exposed to PCBs during the production of the Czechoslovak PCB products Delor 103 and...
Daniel M Moreira et al.
The Journal of urology, 190(6), 2106-2111 (2013-06-15)
We determined the accuracy of 24-hour urinalysis in predicting stone type and identify the associations between 24-hour urine elements with stone type. We performed a retrospective review of 503 stone formers with stone composition analysis and 24-hour urinalysis available. Analysis...
L Rigoli et al.
Acta paediatrica (Oslo, Norway : 1992), 99(5), 722-726 (2010-02-16)
In our study, we evaluated if CART gene A1475G and DeltaA1457 polymorphisms could be associated with obesity. We recruited 133 Italian trios from among 103 (50 males and 53 females) overweight children (mean age 10.5 years, range 6-14 years; mean...
Thiago Mescoloto Lizier et al.
Molecules (Basel, Switzerland), 17(7), 7961-7979 (2012-07-04)
The room temperature ionic liquid (IL) 1-butyl-3-methylimidazolium bis-(trifluorometanesulfonyl)imide BMIm[NTf₂] was used as a novel medium for improvement of separation and quantization of 16 aromatic amines typically present as contaminants in consumer products and detected by HPLC coupled to an electrochemical...
Mark van Duin et al.
Genes, chromosomes & cancer, 44(4), 438-449 (2005-09-01)
Copy number increase of 8q has previously been shown to be associated with a poor clinical outcome and tumor recurrence in patients with prostate cancer. In this study, a detailed genomic analysis of 8q was performed of archival primary and...
Nils Milman et al.
Respiration; international review of thoracic diseases, 74(1), 76-79 (2006-01-07)
Mutations of the caspase-activating recruitment domain 15 (CARD15) gene on chromosome 16 are associated with chronic inflammatory granulomatous bowel disease (Crohn's disease). Sarcoidosis is a systemic granulomatous disease with unknown etiology, which shares histological features with Crohn's disease. To evaluate...
H B Matthews et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 20(4), 477-485 (1993-05-01)
Previous short-term studies of tris(2-chloroethyl)phosphate (TRCP), a flame retardant used in industrial and consumer products, demonstrated that repeated administration of 350 mg TRCP/kg body wt by oral gavage resulted in necrosis of pyramidal neurons in the CA1 region of the...
M A Küper et al.
Diabetic medicine : a journal of the British Diabetic Association, 29(12), 1596-1599 (2012-05-15)
To investigate the relationship between the factor XIII Val34Leu polymorphism, plasma factor XIII activation and transcutaneous oxygen readings in patients with diabetic foot ulcers. Methods  Ninety-two consecutive patients with Type diabetes and active foot ulcers were investigated. Plasma factor XIII...
M Schollenberger et al.
Mycopathologia, 147(1), 49-57 (2000-06-29)
A total of 237 commercially available samples of cereal-based foods including bread and related products, noodles, breakfast cereals, baby and infant foods, rice and other foods were randomly collected in southwest Germany during the first six months of 1998. The...

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon


Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.