Showing 1-27 of 27 results for "106-92-3"
Eiji Akagawa et al.
Biochemical and biophysical research communications, 300(2), 600-608 (2002-12-31)
The receptors for human interleukin-3 (hIL-3R) and granulocyte-macrophage colony-stimulating factor (hGM-CSFR) consist of an alpha subunit, specific for each cytokine, and a beta subunit, common to IL-3, GM-CSF, and IL-5. We cloned genomic DNA covering 1.5 kb of the 5'...
Hiroshi Samoto et al.
The Journal of biological chemistry, 278(31), 28659-28667 (2003-05-27)
Bone sialoprotein (BSP), an early marker of osteoblast differentiation, has been implicated in the nucleation of hydroxyapatite during de novo bone formation. Prostaglandin E2 (PGE2) has anabolic effects on proliferation and differentiation of osteoblasts via diverse signal transduction systems. Because...
Erdembileg Anuurad et al.
Journal of lipid research, 47(11), 2475-2481 (2006-08-05)
We studied the relationship of apolipoprotein E (apoE) isoforms and coronary artery disease (CAD) in 224 African Americans and 326 Caucasians undergoing diagnostic coronary angiography. The presence of CAD was defined as >50% stenosis in at least one artery. ApoE...
Katja Jansen et al.
Macromolecular bioscience, 19(2), e1800412-e1800412 (2018-12-15)
The increasing prevalence of end-stage renal disease and persistent shortage of donor organs call for alternative therapies for kidney patients. Dialysis remains an inferior treatment as clearance of large and protein-bound waste products depends on active tubular secretion. Biofabricated tissues...
Bent T Røen et al.
Analytica chimica acta, 761, 109-116 (2013-01-15)
Three primary nerve agent degradation products (ethyl-, isopropyl- and pinacolyl methylphosphonic acid) have been determined in water samples using on-line solid phase extraction-liquid chromatography and mass spectrometry (SPE-LC-MS) with electrospray ionisation. Porous graphitic carbon was employed for analyte enrichment followed...
Mohammad Faraji et al.
Journal of hazardous materials, 166(2-3), 1383-1388 (2009-01-23)
Copper, as a heavy metal, is toxic for many biological systems. Thus, the determination of trace amounts of copper in environmental samples is of great importance. In the present work, a new method was developed for the determination of trace...
Maoxiao Feng et al.
RNA biology, 12(1), 82-91 (2015-04-01)
Berberine (BBR) is a natural alkaloid derived from a traditional Chinese herbal medicine. However, the exact mechanisms underlying the different effects of berberine on MM cells have not been fully elucidated. A systematic analysis assay integrated common signaling pathways modulated...
R Zolfaghari et al.
Archives of biochemistry and biophysics, 391(1), 8-15 (2001-06-21)
Delta(5)-Desaturase (D5D) catalyzes the Delta(5,6) desaturation of dietary essential fatty acids of the n-6 and n-3 series. By subtraction hybridization of vitamin A (VA)-deficient and control rat liver cDNA libraries, we isolated a 106-bp cDNA fragment that proved to be...
Zhong-Wei Xu et al.
Journal of proteomics, 130, 211-220 (2015-10-06)
Hypoxic status alters the energy metabolism and induces cell injury in cardiomyocytes, and it further triggers the occurrence and development of cardiovascular diseases. Our previous studies have shown that salidroside (SAL) exhibits anti-hypoxic activity. However, the mechanisms remain obscure. In...
Timothy M Cox et al.
Lancet (London, England), 385(9985), 2355-2362 (2015-03-31)
The mainstay of treatment for Gaucher's disease type 1 is alternate-week infusion of enzyme replacement therapy (ERT). We investigated whether patients stable on such treatment would remain so after switching to oral eliglustat, a selective inhibitor of glucosylceramide synthase. In...
Shalini Saggu et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 294(1), R52-R57 (2007-11-09)
Evidence suggests that GABA might mediate the inhibitory influence of centrifugal inputs on taste-evoked responses in the parabrachial nucleus (PBN). Previous studies show that activation of the gustatory cortex (GC), bed nucleus of the stria terminalis (BNST), central nucleus of...
Marzieh Abdolhosseini et al.
Mikrochimica acta, 187(11), 602-602 (2020-10-10)
A new class of polymeric sorbents based on deep eutectic solvents (DESs) is introduced. These materials are obtained from simple and inexpensive precursors via an energy-efficient process. The primary benefit of these sorbents is that they possess the unique characteristics...
S Hirajima et al.
British journal of cancer, 108(9), 1822-1829 (2013-04-13)
Several recent studies demonstrated that microRNAs are stably detectable in plasma/serum. We tested whether miR-18a, which is located in the miR-17-92 cluster and reported to be highly expressed in tissues of oesophageal squamous cell carcinoma (ESCC), served as a plasma...
To Quyen Truong et al.
Cell biochemistry and function, 28(6), 480-489 (2010-07-16)
In non-hepatic cells, scavenger receptor class B type I (SR-BI), cluster of differentiation 36 (CD36), and caveolin-1 were described as mediators of cholesterol efflux, the first step of reverse cholesterol transport (RCT). Stable transformants of HepG2 cells overexpressing SR-BI, CD36...
A L Mark et al.
Journal of hypertension, 17(12 Pt 2), 1949-1953 (2000-03-07)
Recent advances in understanding the neuroendocrine pathways regulating appetite, metabolism and body weight afford an opportunity to explore further the mechanisms by which obesity influences arterial pressure. ob/ob(Lep(ob)/Lep(ob)) mice have a mutation in the ob gene and are leptin-deficient. Leptin...
Daniel Antonio de Luis et al.
The Journal of nutritional biochemistry, 23(3), 287-291 (2011-05-06)
A silent intragenic polymorphism (1359 G/A) of the cannabinoid receptor 1 gene resulting in the substitution of the G to A at nucleotide position 1359 in codon 435 (Thr) was reported as a common polymorphism in Caucasian populations. Intervention studies...
Sergio Lopez et al.
The Journal of nutrition, 143(5), 620-626 (2013-03-15)
Postprandial triglyceride (TG)-rich lipoproteins (TRLs) transport dietary fatty acids through the circulatory system to satisfy the energy and structural needs of the tissues. However, fatty acids are also able to modulate gene expression and/or induce cell death. We investigated the...
Lina Artifoni et al.
The Journal of urology, 177(3), 1102-1106 (2007-02-14)
We performed a case-control study in children diagnosed by the first episode of upper urinary tract infection with or without vesicoureteral reflux to evaluate the association of functional polymorphism of interleukin-8 (-251A>T and +2767A>G), and its receptor CXCR1 (+2607G>C). Genomic...
Michael A Pani et al.
European journal of endocrinology, 146(6), 777-781 (2002-06-01)
The vitamin D endocrine system plays a role in the regulation of (auto)immunity and cell proliferation. Vitamin D 1alpha-hydroxylase (CYP1alpha) is one of the key enzymes regulating both systemic and tissue levels of 1,25-dihyroxyvitamin D(3) (1,25(OH)(2)D(3)). Administration of 1,25(OH)(2)D(3), whose...
Karen H Watanabe et al.
Regulatory toxicology and pharmacology : RTP, 55(2), 123-133 (2009-06-23)
The manner in which humans smoke cigarettes is an important determinant of smoking risks. Of the few investigators that have predicted cancer risks from smoking on a chemical-specific basis, most used mainstream cigarette smoke (MCS) carcinogen emissions obtained via machine...
Jordyn M Boesch et al.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 49(4), 849-855 (2018-12-29)
The effects of etorphine on the pulmonary vascular system of white rhinoceros ( Ceratotherium simum) have not been described and could play a role in the severe hypoxemia that develops after immobilization with etorphine-based drug combinations. Characterization of these effects...
Emma Jane Gault et al.
BMJ (Clinical research ed.), 342, d1980-d1980 (2011-04-16)
To examine the effect of oxandrolone and the timing of pubertal induction on final height in girls with Turner's syndrome receiving a standard dose of growth hormone. Randomised, double blind, placebo controlled trial. Setting 36 paediatric endocrinology departments in UK...
A K Jaiswal
The Journal of biological chemistry, 269(20), 14502-14508 (1994-05-20)
Human NAD(P)H:quinone oxidoreductase2 (NQO2) gene, 1336 base pairs (bp) of the 5'-flanking region and 165 bp of the 3'-flanking region, have been sequenced. NQO2 gene is 20 kilobase pairs in length and have seven exons interrupted by six introns as...
Fernando Maya et al.
Mikrochimica acta, 186(7), 425-425 (2019-06-13)
An ordered array of macropores on microporous metal-organic framework crystals was developed. This array facilitates analyte diffusion in microextraction applications. A prototypical zeolitic imidazolate framework (ZIF-8) was synthesized in the interstitial voids of a polystyrene bead packing of sub-μm polystyrene...
A Minnich et al.
The Journal of biological chemistry, 267(23), 16553-16560 (1992-08-15)
We have mutagenized the human apoA-I gene and have generated cell lines which express normal and mutant apoA-I forms. Point mutations were introduced which changed Gln-1, Gln-2 to Arg,Arg, Pro99 to His, and Pro121 to His. In addition, the following...
Xiao-li Zhu et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 41(9), 584-589 (2012-11-20)
To retrospectively analyze KRAS and BRAF gene mutation features in Chinese colorectal cancer (CRC) and their clinicopathologic relationship. 557 colorectal cancer cases were collected, including 325 colon cancer and 232 rectal cancer. PCR amplification and DNA sequencing were used to...
National Toxicology Program technical report series, (498)(498), 1-277 (2002-07-16)
p-Nitrotoluene is used to synthesize agricultural and rubber chemicals, azo and sulfur dyes, and dyes for cotton, wool, silk, leather, and paper. p-Nitrotoluene was nominated by the National Institute for Occupational Safety and Health and the NTP for study based...

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