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Workflow for Preclinical Monoclonal Antibody Quantification
Pharmacokinetic (PK) kit enables a robust, high-throughput assay for quantification of human IgG1 antibody in animal sera by LC-MS/MS.
NMR Deuterated Solvent Properties Reference Chart
Use this reference table to find the coupling values and chemical shifts of our NMR (deuterated) solvents. Melting and boiling points, molecular weight, density, and CAS number are also listed.
C2-symmetric chiral bisoxazolines (BOX) ligands
C2-symmetric chiral bisoxazolines (BOX) are privileged structures because they promote a great number of transformations with unprecedented selectivity.1
Using Human iPS Cell-derived Colon Organoids for Cytotoxicity Screening of Drug Compounds
Human epithelial intestinal colonic organoids can be used as an alternative to Caco-2 drug permeability assays for drug screening and compound toxicity testing.
QuEChERS Cleanup and Analysis of Veterinary Drugs in Milk by LC/MS/MS
QuEChERS Cleanup and Analysis of Veterinary Drugs in Milk by LC/MS/MS
Extraction of Nitroimidazoles from Milk and Eggs using Molecularly Imprinted Polymers
In this report, SupelMIP SPE – Nitroimidazoles was evaluated for the extraction of nitroimidazoles and metabolites from milk and egg.
Sol-Gel Science for Ceramic Materials
Research involving reactive silicone chemistry has focused on the production of pure silicon and hybrid materials, hydrosilylation, ring-opening and atom transfer polymerizations, polymerizations with controlled stereochemistry, and condensation reactions.
Glycosyltransferases
Glycosyltransferases were initially considered to be specific for a single glycosyl donor and acceptor, which led to the one enzyme-one linkage concept. Subsequent observations have refuted the theory of absolute enzymatic specificity by describing the transfer of analogs of some
Analysis of Pesticide Residues in Pistachios Using QuEChERS Extraction and Cleanup with Supel™ QuE Z-Sep+
Pistachios contain approximately 45% fat, which can result in a significant amount of coextracted matrix in the acetonitrile extract generated using the QuEChERS procedure. A zirconia based adsorbent significantly reduces coextracted matrix prior to LC-MS or GC-MS.
Improved Recoveries and Lower Background for GC/MS/MS and LC/MS/MS Analysis of Pesticides in Green Tea
A procedure for cleanup of green tea extracts provides low background and allowed for the analysis of more pesticides at lower levels than QuEChERS. Uses less solvents and no toluene.
Development of a New Advanced KSOM Mouse Embryo Media that Enables Dual-Use Embryo Culture and Cell Handling Applications
Advanced KSOM mouse embryo media that can be used as a single medium for both harvest and culture of mouse embryos to facilitate creation of transgenic knockout mice.
Periodic Table of the Elements
Download the Periodic Table of the Elements with names, atomic mass and number in printable .pdf and image format. Use the periodic table chart by element names in alphabetical order for quick research, reference and lab use.
Development of Organic Semiconductors from Highly Ordered Oligo and Polythiophenes
The soaring global demand for energy, coupled with the limited supply of fossil fuels, has increased the need for renewable, low-cost energy sources. Organic electronics have shown great promise for applications in lighting, power, and circuitry, with rapidly improving performance
Nanofluids for Biomedical Applications
Currently, magnetic nanoparticles (MNPs) are attracting a lot of attention because of the possibility of many novel applications, especially in biomedical research.
A Comparison of Two Solid Phase Extraction Methods for the Analysis of Polyaromatic Hydrocarbons in Butter
Analysis of PAHs in butter can pose a special challenge due to the high fat content and the lipophilic nature of PAHs.
Synthesis and HILIC/MS Analysis of Acylcarnitines
HILIC mode chromatography using an Ascentis® Express OH5 resolved the majority of the acyl-L-carnitines tested. It may be possible to use MS/MS and particular fragment ions to resolve the two coeluting pairs.
Analysis of Pesticides in Turmeric Powder by LC/MS/MS and GC/MS/MS after Cleanup with Dual-Layer SPE Cartridge
Pesticide residue testing of turmeric and other (dried) spices is challenging due to their complex compositions and high matrix. An efficient SPE clean-up can be achieved by a new Dual-layer cartridge.
Building Blocks for Introducing Post-translational Modified Amino Acids
We provide an overview of our available reagents, together with recommendations and details of their use for synthesis of peptides containing post-translationally modified amino acids.
Glycosyltransferases: Tools for Synthesis and Modification of Glycans
The presence of multiple functional groups and stereocenters in complex carbohydrates makes them challenging targets for the organic chemist.
Silylethyne-Substituted Pentacenes
Silylethyne-Substituted Pentacenes
Carcinogenesis and Epigenetics
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.
DNA Damage and Repair
DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.
Delivery of Nucleic Acids Using Polymers
Delivery of Nucleic Acids Using Polymers
MSI Testing and IHC
Colorectal cancer is a common occurrence among inhabitants of most Western countries, second only to carcinoma of the lung.
TRC Library Citations
TRC 1.5 human and mouse shRNA libraries
Pressure-Temperature Calculator for Solvents
Use the calculator to determine the boiling point or pressure of solvents based on the Antoine Equation and see solvent attributes. View a list of products based on the solvent CAS number.
Recent Advances in Hybrid Halide Perovskites-based Solar Cells
For several decades, the need for an environmentally sustainable and commercially viable source of energy has driven extensive research aimed at achieving high efficiency power generation systems that can be manufactured at low cost.
Albumin from Bovine Serum
Bovine serum albumin (BSA) structure, molecular weight, function, solubility, how BSA is made, purification methods, applications and purchasing.
Immunohistochemistry: Current Applications in Skin Cancer
Immunohistochemistry (IHC) techniques and applications have greatly improved, dermatopathology is still largely based on H&E stained slides.This paper outlines ways in which IHC antibodies can be utilized for dermatopathology.