Showing 1-26 of 26 results for "108-39-4"
L Z Rassenti et al.
The Journal of experimental medicine, 185(8), 1435-1445 (1997-04-21)
We determined the immunoglobulin (Ig) V(H) subgroup expressed by the leukemia cells of 108 patients with B cell chronic lymphocytic leukemia (CLL). Surprisingly, we found that six samples (5%) each expressed Ig of more than one V(H) subgroup. Southern blot...
Lucia Taja-Chayeb et al.
Medical oncology (Northwood, London, England), 25(1), 56-62 (2008-01-12)
Polymorphisms at the thiopurine S-methyltransferase coding gene (TPMT) determine enzyme activity and consequently, the development of toxicity secondary to thiopurines. Methods A total of 108 DNA samples from volunteer donors and 39 from patients with acute lymphoblastic leukemia (ALL) were...
C C Chao et al.
Nucleic acids research, 20(24), 6481-6485 (1992-12-25)
We have recently isolated a functional promoter encoding the human polypeptide-binding protein (BiP) gene from Burkitt's lymphoma cells by polymerase chain reaction (The EMBL Data Library accession number X59969, 1991). This promoter DNA segment (termed BiP670) was fused to the...
M Breidert et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 44(1), 70-74 (2011-12-30)
Serotoninergic 5-HT(4) receptors have been detected in several tissues including the heart. An autoimmune mechanism may underline the pathogenesis of heart failure. The aim of this work was to look for autoantibodies to the 5-HT(4) receptor in patients with heart...
Lana Luiza da Cruz Silva et al.
Scientific reports, 10(1), 9268-9268 (2020-06-11)
Epidermodysplasia verruciformis (EV) is a genodermatosis related to human beta-papillomavirus (beta-HPV), with a high risk of cutaneous squamous cell carcinoma (cSCC). Claudins are transmembrane proteins expressed in epithelia and may be altered during carcinogenesis. For a better understanding of the...
Lucky A Bawazier et al.
Acta medica Indonesiana, 42(4), 192-198 (2010-11-11)
To evaluate the association between ACE gene polymorphism I/D and hypertension in Yogyakarta population. This study is a cross-sectional. Sample was taken by random sampling method from hypertensive, prehypertensve and normotensive subjects; from that were obtained 125 subjects, 97 subjects...
W R Sperr et al.
Blood, 98(7), 2200-2209 (2001-09-25)
alpha- and beta-tryptase genes encode serine proteases that are abundantly expressed by mast cells. Under physiologic conditions other myeloid cells are virtually tryptase negative. However, tryptases are also expressed in several myeloid leukemia cell lines. In this study, serum total...
W R Sperr et al.
Blood, 98(7), 2200-2209 (2001-09-25)
alpha- and beta-tryptase genes encode serine proteases that are abundantly expressed by mast cells. Under physiologic conditions other myeloid cells are virtually tryptase negative. However, tryptases are also expressed in several myeloid leukemia cell lines. In this study, serum total...
H Laayouni et al.
Genetics, 156(4), 1797-1816 (2000-12-05)
We present a physical map based on RAPD polymorphic fragments and sequence-tagged sites (STSs) for the repleta group species Drosophila buzzatii. One hundred forty-four RAPD markers have been used as probes for in situ hybridization to the polytene chromosomes, and...
Kayo Nishimatsu et al.
Annals of nuclear medicine, 29(9), 766-771 (2015-07-15)
In positron emission tomography (PET) with F-18-fluorodeoxyglucose (FDG), non-tumorous focal uptake is often observed around the lumbar spinous processes (LSPs). Close approximation of LSPs with sclerosis is often seen, which is called Baastrup disease. The aim of this study was...
Sandra S Wise et al.
Toxicology and applied pharmacology, 279(2), 113-118 (2014-06-22)
Sea turtles are a charismatic and ancient ocean species and can serve as key indicators for ocean ecosystems, including coral reefs and sea grass beds as well as coastal beaches. Genotoxicity studies in the species are absent, limiting our understanding...
S Banerjee et al.
Health technology assessment (Winchester, England), 17(7), 1-166 (2013-02-27)
Depression is common in dementia, causing considerable distress and other negative impacts. Treating it is a clinical priority, but the evidence base is sparse and equivocal. This trial aimed to determine clinical effectiveness of sertraline and mirtazapine in reducing depression...
Eman Mosad et al.
Oncology, 83(3), 128-134 (2012-07-21)
Therapy-related acute myeloid leukemias (t-AML), with balanced translocations affecting the 11q23 point in the myeloid/lymphoid leukemia (MLL) gene, are one of the most serious complications of treatments with topoisomerase II inhibitors. However, only a few reports of t-AML exist. We...
Genovefa D Kolovou et al.
Angiology, 56(6), 663-670 (2005-12-06)
Apolipoprotein (apo) E polymorphism has been associated with coronary heart disease (CHD) although its relation to the age of CHD onset is still not defined. The age of onset of established CHD was obtained from 502 Greek men and compared...
Kristen A Neville et al.
Clinical endocrinology, 82(5), 657-662 (2015-01-20)
It is unclear whether the rate of vitamin D deficiency in paediatric cancer survivors is higher than in the background population, and whether this is of pathological significance. 25OHD was measured in a previously studied group of 208 survivors (n...
Jennifer A Rymer et al.
Journal of the American Heart Association, 8(10), e012236-e012236 (2019-05-10)
Background Although recommended in the guidelines, the safety of chronic P2Y12 inhibitor therapy in patients with chronic kidney disease ( CKD ) after an acute myocardial infarction ( MI ) is not well studied. Methods and Results The TRANSLATE -ACS...
Vered Stearns et al.
Journal of the National Cancer Institute, 95(23), 1758-1764 (2003-12-05)
Tamoxifen, a selective estrogen receptor modulator (SERM), is converted to 4-hydroxy-tamoxifen and other active metabolites by cytochrome P450 (CYP) enzymes. Selective serotonin reuptake inhibitors (SSRIs), which are often prescribed to alleviate tamoxifen-associated hot flashes, can inhibit CYPs. In a prospective...
Agustin Castiella et al.
Annals of hepatology, 14(3), 333-339 (2015-04-13)
There are limited data on clinical and phenotypic characteristics of outpatients referred for hyperferritinemia (HF). To determine the causes of HF in outpatients referred to a secondary hospital. A prospective study of 132 consecutive patients with HF (> 200 μg/L...
Byungnam Kim et al.
Radiation research, 190(3), 309-321 (2018-06-19)
During the pulsed-electron beam direct grafting of neat styrene onto poly(tetrafluoroethylene-co-hexafluoropropylene) (FEP) substrate, the radiolytically-produced styryl and carbon-centered FEP radicals undergo various desired and undesired competing reactions. In this study, a high-dose rate is used to impede the undesired free...
J V Cohen et al.
Familial cancer, 11(1), 69-75 (2011-09-08)
Risk-reducing salpingo-oophorectomy (RRSO) significantly reduces the risk of ovarian cancer and breast cancer in pre-menopausal women with BRCA1 and BRCA2 (B1/2) mutations. Despite its clear benefits, little is known about non-cancer endpoints in this population. Medical records were examined in...
D Nicholas Bateman et al.
Lancet (London, England), 383(9918), 697-704 (2013-12-03)
Paracetamol poisoning is common worldwide. It is treated with intravenous acetylcysteine, but the standard regimen is complex and associated with frequent adverse effects related to concentration, which can cause treatment interruption. We aimed to ascertain whether adverse effects could be...
Sofia Lagerholm et al.
Bone, 47(6), 1039-1047 (2010-08-12)
The F344 rat carries alleles contributing to bone fragility while the GK rat spontaneously develops type-2 diabetes. These characteristics make F344×GK crosses well suited for the identification of genes related to bone size and allow for future investigation on the...
Adám Balogh et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 244(8), 1035-1038 (2005-12-20)
Retinopathy of prematurity (ROP) is a potentially blinding eye disorder that affects premature infants. Insulin-like growth factor I (IGF-I) has been established as being necessary for vascular growth in the neonatal retina. Low IGF-I levels during the early postnatal days...
Michael Knösel et al.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 144(1), 86-96 (2013-07-03)
White spot lesions that form during orthodontic treatment are a problem for patients and clinicians. Lesion infiltration with low-viscosity light-cured resin has been proposed as a treatment to inhibit further demineralization. The purpose of this study was to assess the...
Frédéric Chibon et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 22(3), 403-409 (2008-12-09)
Most Her2 testing guidelines recommend that all cases scoring Her2 2+ by immunohistochemistry should be analyzed by fluorescent in situ hybridization (FISH) to determine HER2 status to confirm eligibility for Trastuzumab therapy in breast cancer. The aim of our study...
Gunter von Minckwitz et al.
The Lancet. Oncology, 15(7), 747-756 (2014-05-06)
Preclinical data suggest that triple-negative breast cancers are sensitive to interstrand crosslinking agents, and that synergy may exist for the combination of a taxane, trastuzumab, and a platinum salt for HER2-positive breast cancer. We therefore aimed to assess the efficacy...

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