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Showing 1-30 of 36 results for "109-67-1" within Papers
Makito Miyake et al.
Urologia internationalis, 85(3), 355-363 (2010-08-25)
In several malignant diseases, elevated heme oxygenase-1 (HO-1) is associated with progression or resistance to chemotherapy. We evaluated the clinical significance of HO-1 expression in non-muscle-invasive bladder cancer. We examined 109 patients with non-muscle-invasive bladder cancer. The immunoexpression of HO-1
Tingting Gu et al.
Oncology letters, 14(6), 6815-6822 (2018-02-10)
The present study explored the expression of tetraspanin 1 (TSPAN1) in esophageal carcinoma (EC) and its association with clinicopathological factors. TSPAN1 small interfering RNA (siRNA) was designed to target the TSPAN1 gene in Eca-109 cells in order to explore the
Guillaume Blanc et al.
The Journal of biological chemistry, 282(23), 16924-16933 (2007-04-21)
Procollagen C-proteinase enhancers (PCPE-1 and -2) are extracellular glycoproteins that can stimulate the C-terminal processing of fibrillar procollagens by tolloid proteinases such as bone morphogenetic protein-1. They consist of two CUB domains (CUB1 and -2) that alone account for PCPE-enhancing
Nobuyuki Yanagisawa et al.
Cancer biomarkers : section A of Disease markers, 15(4), 365-374 (2015-04-04)
Oncocytic L-amino acid transporter (LAT) 1 could be a target of new molecular therapy against malignancies. To assess the correlation between overexpression of LAT1 and local progression (LP) in prostatic carcinoma (PC) patients under expectant management (EM). This retrospective study
S Fogli et al.
Therapeutic drug monitoring, 21(3), 367-375 (1999-06-12)
A single high-performance liquid chromatography (HPLC) method, suitable for the analysis of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites is validated in the present study. Preparation of plasma samples was performed by a first extraction of analytes with a
Marc Decobert et al.
The Journal of urology, 175(4), 1506-1511 (2006-03-07)
Superficial bladder tumors have a high recurrence rate and 10% to 20% of recurrences progress to invasive cancer. Recurrence and progression can best be prevented by nonspecific immunotherapy using intravesical BCG instillations. The NRAMP1 gene has been implicated in susceptibility
Yvonne Ackermann et al.
Journal of agricultural and food chemistry, 59(12), 6360-6368 (2011-05-04)
This study investigated the production of polyclonal (pAB) antibodies and the first time production of monoclonal (mAB) antibodies against the mycotoxin alternariol, and their implementation in enzyme immunoassay (EIA) for the rapid determination of alternariol in foods. Both EIAs were
Marianne O Larsen et al.
American journal of physiology. Endocrinology and metabolism, 282(6), E1342-E1351 (2002-05-15)
Nonrodent models of diabetes are needed for practical and physiological reasons. Induction of mild insulin-deficient diabetes was investigated in male Göttingen minipigs by use of streptozotocin (STZ) alone (75, 100, and 125 mg/kg) or 125 mg/kg combined with pretreatment with
Alba M Redondo et al.
British journal of haematology, 184(5), 797-807 (2018-12-15)
We conducted a phase 2 trial to evaluate the safety and efficacy of bendamustine instead of BCNU (carmustine) in the BEAM (BCNU, etoposide, cytarabine and melphalan) regimen (BendaEAM) as conditioning for autologous stem-cell transplantation (ASCT) in patients with aggressive lymphomas.
Takashi Suzuki et al.
Cancer science, 98(5), 644-651 (2007-03-16)
Cyclin B1 is translocated to the nucleus from the cytoplasm, and plays an essential role in cell proliferation through promotion of mitosis. Although overexpression of cyclin B1 was previously reported in breast carcinomas, the biological significance of the intracellular localization
Takashi Suzuki et al.
Cancer science, 98(5), 644-651 (2007-03-16)
Cyclin B1 is translocated to the nucleus from the cytoplasm, and plays an essential role in cell proliferation through promotion of mitosis. Although overexpression of cyclin B1 was previously reported in breast carcinomas, the biological significance of the intracellular localization
Yumiko Kawabata et al.
Diabetes, 51(2), 545-551 (2002-01-29)
To assess the effect of Asian-specific HLA haplotypes on susceptibility to type 1 diabetes, we investigated the association of genotypic combinations of DRB1-DQB1 haplotypes with susceptibility to type 1 diabetes. We studied 132 Japanese patients with type 1 diabetes and
Christine Rivat et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 17(12), 1721-1723 (2003-09-06)
The matrix metalloprotease matrilysin is expressed in premalignant polyps and plays a key role in local invasion during the progression of digestive tumors. In the present work, we investigated the possible relationships between the activity of the mouse and human
Christine Rivat et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 17(12), 1721-1723 (2003-09-06)
The matrix metalloprotease matrilysin is expressed in premalignant polyps and plays a key role in local invasion during the progression of digestive tumors. In the present work, we investigated the possible relationships between the activity of the mouse and human
H Minoda et al.
Fukuoka Shika Daigaku Gakkai zasshi, 17(3), 324-331 (1990-01-01)
A 67-year-old Japanese housewife, who had been attended the out patient department of medicine, Fukuoka Dental College (FDC) Hospital for paroxysmal atrial fibrillation, was admitted to FDC Hospital because of high fever, exhaustion, anorexia, myalgia and mild stupor. Her ECG
K K Gnanalingham et al.
Biochemical pharmacology, 49(9), 1185-1193 (1995-05-11)
The ability of benzazepine D-1 dopamine agonists with varying efficacies in stimulating adenylate cyclase and to induce contralateral circling was investigated in rats with unilateral 6-hydroxydopamine lesions of the medial forebrain bundle. In the 6-hydroxydopamine lesioned rats, the benzazepines SKF
Irene Friligou et al.
Amino acids, 40(5), 1431-1440 (2010-09-28)
A fast and efficient microwave-assisted solid phase peptide synthesis (MW-SPPS) of a 51mer peptide, the main heparin-binding site (60-110) of human pleiotrophin (hPTN), using 2-chlorotrityl chloride resin (CLTR-Cl) following the 9-fluorenylmethyloxycarbonyl/tert-butyl (Fmoc/tBu) methodology and with the standard N,N'-diisopropylcarbodiimide/1-hydroxybenzotriazole (DIC/HOBt) coupling
Yung-Kuo Lin et al.
Basic research in cardiology, 107(5), 293-293 (2012-08-14)
Obesity is an important risk factor for atrial fibrillation (AF). Increased epicardial adipose tissue in obesity can enhance inflammation and plays an important role in the pathophysiology of AF. However, it is not clear whether epicardial adipocytes directly modulate the
K Ray et al.
The Journal of biological chemistry, 275(44), 34245-34251 (2000-08-18)
Metabotropic glutamate receptor 1 (mGluR1) expresses at the cell surface as disulfide-linked dimers and can be reduced to monomers with sulfhydryl reagents. To identify the dimerization domain, we transiently expressed in HEK-293 cells a truncated version of mGluR1 (RhodC-R1) devoid
K Ray et al.
The Journal of biological chemistry, 275(44), 34245-34251 (2000-08-18)
Metabotropic glutamate receptor 1 (mGluR1) expresses at the cell surface as disulfide-linked dimers and can be reduced to monomers with sulfhydryl reagents. To identify the dimerization domain, we transiently expressed in HEK-293 cells a truncated version of mGluR1 (RhodC-R1) devoid
Benhong Xu et al.
Experimental gerontology, 73, 31-41 (2015-12-04)
The temporal lobe is a portion of the cerebral cortex with critical functionality. The age-related protein profile changes in the human temporal lobe have not been previously studied. This 4-plex tandem mass tag labeled proteomic study was performed on samples
Paul L Nguyen et al.
Urologic oncology, 29(3), 302-308 (2009-05-20)
In several human cancers, overexpression of Skp2 (S-phase kinase associated protein 2), which targets p27 for degradation, portends a poorer prognosis. We examined whether Skp2 overexpression is associated with recurrence following radical prostatectomy (RP) for prostate cancer. Immunohistochemical staining for
Anne Couvelard et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(20), 6634-6639 (2008-10-18)
Tumor hypoxia is associated with poor prognosis and resistance to treatment. Our aim was to assess the expression of proteins that act as cellular oxygen sensors, directly regulating the hypoxia inducible factor (HIF) pathway, i.e., prolyl hydroxylase domain proteins (PHD)-1
Ingeborg M Bachmann et al.
BMC cancer, 8, 362-362 (2008-12-09)
Tumor necrosis and apoptotic activity are considered important in cancer progression, but these features have not been much studied in melanomas. Our hypothesis was that rapid growth in cutaneous melanomas of the vertical growth phase might lead to tissue hypoxia
A Caron et al.
Domestic animal endocrinology, 72, 106408-106408 (2020-02-03)
The objective of this project was to determine the effects of sustained hyperprolactinemia for 7 or 20 d on mammary development in late-pregnant gilts. On day 90 of gestation, gilts were assigned to one of 3 groups to receive intramuscular (IM)
M Higashiyama et al.
Cancer research, 55(24), 6040-6044 (1995-12-15)
Motility related protein-1 (MRP-1) is a transmembrane glycoprotein that is identical to the CD9 antigen. In previous studies, we showed that various types of cultured tumor cells transfected with MRP-1/CD9 cDNA have low motility and diminished metastatic potential to the
M Bassi et al.
Acta physiologica (Oxford, England), 213(4), 893-901 (2014-09-11)
Melanocortin receptors (MC3/4R) mediate most of the metabolic and cardiovascular actions of leptin. Here, we tested if MC4R also contributes to leptin's effects on respiratory function. After control measurements, male Holtzman rats received daily microinjections of leptin, SHU9119 (MC3/4R antagonist)
Julien Januszkiewicz et al.
Journal of chromatography. A, 1195(1-2), 16-24 (2008-05-23)
A headspace solid-phase microextraction (HS-SPME) combined with gas chromatography-mass spectrometry (GC/MS) method was developed using experimental designs to quantify the flavor of commercial Cheddar cheese and enzyme-modified Cheddar cheese (EMCC). Seven target compounds (dimethyl disulfide, hexanal, hexanol, 2-heptanone, ethyl hexanoate
Hong Xie et al.
Mutation research, 586(2), 160-172 (2005-08-23)
Hexavalent chromium (Cr(VI)) is a widespread environmental contaminant and a known human carcinogen, generally causing bronchial cancer. Recent studies have shown that the particulate forms of Cr(VI) are the potent carcinogens. Particulate Cr(VI) is known to induce a spectrum of
Nicoletta F Maounis et al.
Histology and histopathology, 27(9), 1183-1194 (2012-07-19)
We and others have previously shown that increased expression and altered compartmentalization of γ-tubulin may contribute to tumorigenesis and tumor progression (J. Cell Physiol. 2009;223:519-529; Cancer Biol. Ther. 2010;9:66-76). Here we have determined by immunohistochemistry the localization and cellular distribution
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