Showing 1-15 of 15 results for "110-89-4"
An-ping Xu et al.
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 24(10), 1107-1112 (2004-10-16)
To investigate the possible association of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) promoter -1722 polymorphism with systemic lupus erythematosus (SLE) in the population in southern China. A total of 103 SLE patients (13 males and 90 females with an average...
M M M Abd-Elnaeim et al.
Reproduction in domestic animals = Zuchthygiene, 44(2), 312-319 (2008-11-11)
The functions of placental oestrogens during equine pregnancy are still unclear. Yet, they may act predominantly as local regulators of growth and differentiation in the microplacentomes. Thus, expression patterns of oestrogen receptors (ERs) alpha and beta were investigated in the...
Anastasia Papaporfyriou et al.
Chest, 146(4), 951-958 (2014-06-06)
Osteopontin (OPN) is a phosphorylated acidic glycoprotein that can function as both an extracellular matrix molecule and a cytokine. Published data support that OPN is upregulated in surgical lung tissue samples of patients with COPD. The aim of this study...
Keita Itatsu et al.
The American journal of pathology, 174(3), 829-841 (2009-02-17)
Matrix metalloproteinase-9 (MMP-9) is an important enzyme in tumor invasion and metastasis in malignant tumors, including cholangiocarcinoma (CC). Tumor necrosis factor-alpha (TNF-alpha), a proinflammatory cytokine, was recently reported to induce the up-regulation of MMP-9 in cultured CC cells. We examined...
Anahita Torkaman-Boutorabi et al.
Clinical and experimental pharmacology & physiology, 34(11), 1207-1211 (2007-09-21)
1. Xenobiotic-metabolizing enzymes constitute an important line of defence against a variety of carcinogens. Many are polymorphic, constituting the basis for the wide interindividual variation in metabolic capacity and possibly a source of variation in the susceptibility to chemical-induced carcinogenesis....
Romina Kohan et al.
Gene, 516(1), 114-121 (2012-12-26)
Tripeptidyl-peptidase 1 (TPP1) null or residual activity occurs in neuronal ceroid lipofuscinosis (NCL) with underlying TPP1/CLN2 mutations. A survey of 25 South American CLN2 affected individuals enabled the differentiation of two phenotypes: classical late-infantile and variant juvenile, each in approximately...
F Van Leuven et al.
Atherosclerosis, 154(3), 567-577 (2001-03-21)
Five coding polymorphisms in de LRP1 gene, i.e. A217V, A775P, D2080N, D2632E and G4379S were discovered by sequencing its 89 exons in three test-groups of 22 healthy individuals, 29 Alzheimer patients and 18 individuals with different clinical and molecularly uncharacterized...
Xiao C Li et al.
American journal of physiology. Cell physiology, 294(4), C1034-C1045 (2008-02-08)
The present study tested the hypothesis that intracellular ANG II directly induces transcriptional effects by stimulating AT(1a) receptors in the nucleus of rat renal cortical cells. Intact nuclei were freshly isolated from the rat renal cortex, and transcriptional responses to...
Mathewos Tessema et al.
Carcinogenesis, 35(6), 1248-1257 (2014-01-09)
Lung cancer in never smokers (NS) shows striking demographic, clinicopathological and molecular distinctions from the disease in smokers (S). Studies on selected genetic and epigenetic alterations in lung cancer identified that the frequency and profile of some abnormalities significantly differ...
Matthew P Goetz et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(18), 5864-5868 (2008-09-17)
Genetic variation in cytochrome P450 2D6 (CYP2D6) and the gene expression ratio of the homeobox 13 (HOXB13) to interleukin-17B receptor (IL17BR) are associated with tamoxifen resistance. We sought to determine the combined effect of inherited (CYP2D6) and somatic (HOXB13/IL17BR) gene...
C Boltze et al.
Verhandlungen der Deutschen Gesellschaft fur Pathologie, 88, 237-245 (2006-08-09)
The presented study was aimed to investigate new mechanisms of carcinogenesis in thyroids at the molecular level and to find potential protein markers involved in the initiation of the different histological subtypes of thyroid carcinoma. For this, we performed differential...
Jinru Shia et al.
The American journal of surgical pathology, 29(1), 96-104 (2004-12-23)
The utility of immunohistochemistry (IHC) as a screening method for the identification of persons with mutations in the DNA mismatch repair (MMR) genes in hereditary nonpolyposis colorectal cancer (HNPCC) remains to be defined. In this study, we analyzed the value...
G Liu et al.
Molecular pharmacology, 45(2), 189-200 (1994-02-01)
The fluorogenic sulfhydryl probe 7-diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin (CPM) (1-50 nM) is used to characterize the functional role and location of highly reactive thiol groups on the ryanodine-sensitive Ca2+ release channel complex [i.e., ryanodine receptors (RyRs)] of skeletal and cardiac junctional sarcoplasmic reticulum...
Andre R Nelson et al.
Medicine and science in sports and exercise, 44(1), 57-68 (2011-06-21)
This study aimed to determine the effect of postexercise protein-leucine coingestion with CHO-lipid on subsequent high-intensity endurance performance and to investigate candidate mechanisms using stable isotope methods and metabolomics. In this double-blind, randomized, crossover study, 12 male cyclists ingested a...
National Toxicology Program technical report series, 428, 1-275 (1993-12-01)
Manganese is the 12th most abundant element in the earth's crust. The base metal does not occur naturally, but is a component of more than 100 minerals, including sulfides, oxides, carbonates, silicates, phosphates, and borates. In addition to occurring in...

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