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Chromatographic Purification of Plasmid DNA (pDNA) for mRNA, Plasmid-based DNA Vaccines, and Viral Vector Applications
See case study examples of how to optimize chromatographic purification of plasmid DNA for Biopharmaceutical Applications.
Fabricación de vacunas basadas en virus
La fabricación de vacunas víricas a medida aborda los retos específicos del virus mediante la colaboración.
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Cost Modeling Vaccine Manufacturing: Estimate Production Costs for mRNA and other Vaccine Modalities
A custom-designed cost model is used to explore the economics of vaccine manufacturing across several different modalities including mRNA. The model enables greater process understanding, simulates bottlenecks, and helps to optimize production efficiency.
Egg-based and Cell-based Influenza Vaccine Manufacturing Methods
Influenza vaccines are commonly made using egg-based and cell-based manufacturing strategies. Find step-by-step information on the manufacturing process for each method.
Adenovirus Vaccine Manufacturing Process
This technical article breaks down the adenovirus vaccine manufacturing process and provides a case study on developing an accelerated and cost-effective single-use adenoviral vector vaccine.
Developing and Manufacturing Attenuated Viral Vaccines
Learn more one the attenuated viral vaccines manufacturing process: cell culture, clarification, nuclease treatment, chromatography, and sterile filtration.
Virus-like Particle (VLP) Vaccine Bioprocessing and Formulation Steps
This technical article breaks down the steps of upstream and downstream bioprocessing and formulation of virus-like particle vaccines.
mRNA Process & Cost Modeling: Optimize Development
A cost-model compares modalities like viral vectors and mRNA for production scale decision-making.
Successfully Navigate the Regulatory Landscape for Chemicals and Single-Use Consumables
This page summarizes key considerations related to regulatory expectations for biomanufacturing including chemicals and polymeric materials. For chemicals, topics include nitrosamines and elemental impurities, and for polymeric materials such as filters and single-use assemblies, the focus is qualification and extractable
Plasmid DNA Purification Process
Free eBook outlines plasmid DNA manufacturing process and downstream purification challenges for various applications.
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