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Zhiyong Lei et al.
Frontiers in physiology, 11, 590-590 (2020-07-03)
Background: Myocardial infarction (MI) is caused by occlusion of the coronary artery and induces ischemia in the myocardium and eventually a massive loss in cardiomyocytes. Studies have shown many factors or treatments that can affect the healing and remodeling of
G J Chang et al.
Genetics and molecular research : GMR, 14(3), 8509-8515 (2015-09-09)
In the mammalian genome, approximately 50% of all genes are controlled by promoters with high GC contents. Analyzing the epigenetic mechanisms regulating their expression is difficult. Hence, we examined a method for stable quantification of such GC-rich DNA sequences. Quantification
Oliver J Bower et al.
Current protocols, 1(8), e232-e232 (2021-08-26)
CRISPR-Cas9 mutagenesis facilitates the investigation of gene function in a number of developmental and cellular contexts. Human pluripotent stem cells (hPSCs), either embryonic or induced, are a tractable cellular model to investigate molecular mechanisms involved in early human development and
Zhiyong Lei et al.
Journal of cellular and molecular medicine, 19(8), 1994-2005 (2015-05-07)
Arteriogenesis is a complicated process induced by increased local shear-and radial wall-stress, leading to an increase in arterial diameter. This process is enhanced by growth factors secreted by both inflammatory and endothelial cells in response to physical stress. Although therapeutic
Induction of autophagy with catalytic mTOR inhibitors reduces huntingtin aggregates in a neuronal cell model.
Roscic A, et al.
Journal of Neurochemistry, 119(2), 398-407 (2011)
Micro RNA?132/212 family enhances arteriogenesis after hindlimb ischaemia through modulation of the Ras?MAPK pathway.
Lei Z, et al.
Journal of Cellular and Molecular Medicine, 19(8), 1994-2005 (2015)
C Ronald Scott et al.
The Journal of pediatrics, 163(2), 498-503 (2013-03-08)
To assess the performance of a tandem mass spectrometry (MS/MS) technology in a newborn screening laboratory to simultaneously measure α-galactosidase, acid-α-glucosidase, and α-L-iduronidase for the detection of infants at risk to develop Fabry, Pompe, or mucopolysaccharidosis (MPS)-I diseases. Enzyme activity
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