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K Taniguchi et al.
The Journal of biological chemistry, 258(11), 6927-6931 (1983-06-10)
The addition of ATP to (Na+,K+)-ATPase (EC of pig kidney modified with N-[p-(2-benzimidazolyl)phenyl]maleimide induced three different modes of fluorescence change: positive, biphasic, and negative, which were observed, respectively, in the presence of Mg2+ with 16 or 160, 320 or
C Emmanouil et al.
Aquatic toxicology (Amsterdam, Netherlands), 82(1), 27-35 (2007-03-03)
The oxidation of DNA and lipid was analysed in the marine mussel (Mytilus edulis) in response to exposure (10microg/l and 200microg/l) to cadmium (Cd) and chromium [Cr(VI)]. Concentration dependent uptake of both metals into mussel tissues was established and levels
Amanda J Lee et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 14(2), 497-505 (2005-03-01)
Although the genotoxic mechanism(s) of hexavalent chromium (CrVI) carcinogenicity remain to be fully elucidated, intracellular reduction of CrVI and concomitant generation of reactive intermediates including reactive oxygen species and subsequent oxidative damage to DNA is believed to contribute to the
[Practical analysis of toxic substances useful for clinical toxicology-12-methanol].
Yasushi Hori et al.
Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 17(4), 371-376 (2005-02-01)
Huoy-Rou Chang et al.
Toxicology in vitro : an international journal published in association with BIBRA, 25(1), 1-6 (2010-07-06)
Chromium (Cr) is considered to be a risk factor to the cardiovascular effects of fine particulate matter components to PM2.5 from traffic in highway patrol officers. RKIP (raf kinase inhibitor protein) is a physiological inhibitor of GRK-2 (G-protein-coupled receptor kinase
Maria Sahagia et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 140, 146-150 (2018-07-18)
The absolute standardization of Co-57 by the 4π(PC)-γ coincidence method, in efficiency extrapolation variant, is presented. An original, improved method, based on the use of the equivalent decay scheme, was applied; apart from the enhancement of efficiency, a diminution of
Katsunori Yanagihara et al.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 23(9), 587-597 (2017-07-04)
The nationwide surveillance on antimicrobial susceptibility of bacterial respiratory pathogens from the patients in Japan was conducted by Japanese Society of Chemotherapy, Japanese association for infectious diseases and Japanese society for Clinical Microbiology in 2012. The isolates were collected from
Xin Wang et al.
Toxicological sciences : an official journal of the Society of Toxicology, 123(2), 399-410 (2011-07-12)
Hexavalent chromium [Cr(VI)] is a well-known human carcinogen associated with the incidence of lung cancer. Although overproduction of reactive oxygen species (ROS) has been suggested to play a major role in its carcinogenicity, the mechanisms of Cr(VI)-induced ROS production remain
P Apostoli et al.
Giornale italiano di medicina del lavoro ed ergonomia, 31(2), 177-181 (2009-10-16)
In this paper the update of directive 67/548/EEC published in Official Journal of the European Union on 16 January 2009 proposes about carcinogenicity of metallic elements is reported and discussed. The main change is represented by the classification R49 and
Hugo Kerdoncuff et al.
Optics letters, 44(20), 5057-5060 (2019-10-16)
Raman spectroscopy is an appealing technique that probes molecular vibrations in a wide variety of materials with virtually no sample preparation. However, accurate and reliable Raman measurements are still a challenge and require more robust and practical calibration methods. We
M Rajasimman et al.
Journal of hazardous materials, 168(1), 291-297 (2009-03-17)
The emulsion liquid membrane technique was used for the extraction of hexavalent chromium ions from aqueous solution of waste sodium dichromate recovered from the pharmaceutical industry wastewater. The liquid membrane used was composed of kerosene oil as the solvent, Span-80
Zhai Suoqiang et al.
Cell biochemistry and biophysics, 62(2), 403-406 (2011-11-08)
Microcirculatory disturbance of inner ear is probably one of the important etiological factors of sudden deafness. The purpose of this study was to evaluate the effect of retreatment on the end-stage sudden deafness. For this purpose, the patients who met
Y. Kanaoka
Angewandte Chemie (International Edition in English), 89, 142-142 (1977)
Robert J W Brewin et al.
Sensors (Basel, Switzerland), 19(4) (2019-03-01)
Two expanding areas of science and technology are citizen science and three-dimensional (3D) printing. Citizen science has a proven capability to generate reliable data and contribute to unexpected scientific discovery. It can put science into the hands of the citizens
N J Hodges et al.
Toxicology, 197(2), 101-112 (2004-03-09)
Changes in the components of the Jun N-terminal kinase (JNK) signalling pathway were investigated in human A549 lung carcinoma cells treated with sodium dichromate. Sodium dichromate (100 microM, 0-6h) failed to activate nuclear factor kappa B (NF-kappaB) as determined by
Boon-Hong Wee et al.
Nanoscale, 7(42), 17805-17811 (2015-10-13)
This article describes the effect of the lateral size of graphene oxide (GO) on the humidity sensing properties of a GO-based sensor. The GO size effect on the humidity sensing performance was evaluated on gold electrodes drop-coated with either an
K Taniguchi et al.
Journal of biochemistry, 109(2), 299-306 (1991-02-01)
Oligomycin reduced the fluorescence intensity of an N-(p-(2-benzimidazoly)phenyl) maleimide (BIPM) probe at Cys-964 of the alpha-chain of pig kidney Na+,K(+)-ATPase with increase in the concentration of Na+ with a Hill coefficient of nh = 0.77 with Kh = 231 mM.
Wonhwa Lee et al.
International journal of molecular sciences, 21(4) (2020-02-27)
The screening of biologically active chemical compound libraries can be an efficient way to reposition Food and Drug Adminstration (FDA)-approved drugs or to discover new therapies for human diseases. Particulate matter with an aerodynamic diameter equal to or less than
Pulane E Molokwane et al.
Water research, 42(17), 4538-4548 (2008-09-02)
A mixed-culture of bacteria collected from a wastewater treatment plant in Brits, North-West Province (South Africa) biocatalytically reduced Cr(VI) at much higher concentrations than previously observed in cultures isolated in North America. Cr(VI) reduction rate up to 8 times higher
Li-Wei Liu et al.
Frontiers in pharmacology, 11, 502-502 (2020-05-12)
The drug combination of biapenem (BIPM) and xuebijing injection (XBJ) is commonly applied for the treatment of sepsis in China. However, the potential synergistic mechanism is still enigmatic. There have been no studies focused on the plasma metabolome alterations in
Bradley J Collins et al.
Toxicological sciences : an official journal of the Society of Toxicology, 118(2), 368-379 (2010-09-17)
In National Toxicology Program 2-year studies, hexavalent chromium [Cr(VI)] administered in drinking water was clearly carcinogenic in male and female rats and mice, resulting in small intestine epithelial neoplasms in mice at a dose equivalent to or within an order
Stephen Boyle et al.
The Science of the total environment, 404(1), 56-67 (2008-07-22)
The entomopathogenic nematode (EPN), Steinernema feltiae, is a commonly occurring nematode in the soil in Ireland. Consequently, we have conducted investigations as to the utility of this species as a candidate organism for the detection of chromium in Irish soils.
[Calculating risk and relative genetic effects of some alkylating agents].
M G Domshlak
Meditsina truda i promyshlennaia ekologiia, (9)(9), 33-39 (2003-11-05)
Isabelle Hininger et al.
Free radical biology & medicine, 42(12), 1759-1765 (2007-05-22)
Several studies have demonstrated beneficial effects of supplemental trivalent Cr in subjects with reduced insulin sensitivity with no documented signs of toxicity. However, recent studies have questioned the safety of supplemental trivalent Cr complexes. The objective of this study was
Chad M Thompson et al.
Regulatory toxicology and pharmacology : RTP, 64(1), 68-76 (2012-06-19)
In vitro studies on hexavalent chromium [Cr(VI)] indicate that reduced forms of this metal can interact with DNA and cause mutations. Recently, Cr(VI) was shown to induce intestinal tumors in mice; however, Cr(VI) elicited redox changes, cytotoxicity and hyperplasia -
Sydney H Kaufman et al.
The journal of physical chemistry. A, 117(10), 2144-2151 (2013-02-21)
In the present study, we investigate the spectroscopy and photochemical behavior of chromate ester cluster ions in vacuo in the visible and near-UV. Chromate ester cluster ions Na(n)[CrO3(OCH3)](n+1)(-) (n = 1, 2) are generated by electrospray ionization of sodium dichromate
S Inoue et al.
Japanese journal of pharmacology, 43(1), 107-111 (1987-01-01)
Trypsin treatment of N-[p-(2-benzimidazolyl)phenyl]maleimide modified enzyme caused a marked reduction in Na+,K+-ATPase activity and in the amount of the alpha-chain, which contains the phosphorylation and ouabain binding sites. However, these preparations retained nearly 90% of the ouabain binding capacity and
Y Nakamura et al.
Journal of biochemistry, 115(3), 454-462 (1994-03-01)
Phospholipase A2 [EC] treatment of pig kidney Na+,K(+)-ATPase [EC] labeled with fluorescence probes at the alpha-chain reduced the extent of the fluorescence intensity change of an N-[p-(2-benzimidazolyl)phenyl]maleimide (BIPM) probe at Cys-964 to below one-third of the control level
Fluorescent thiol reagents. V. Microfluorometry of thiol compounds with a fluorescent-labeled maleimide.
T Sekine et al.
Analytical biochemistry, 48(2), 557-568 (1972-08-01)
Silvio De Flora et al.
Mutation research, 610(1-2), 38-47 (2006-07-29)
Chromium(VI) compounds are genotoxic in a variety of cellular systems. Their potential carcinogenicity is affected by toxicokinetic patterns restricting bioavailability to certain targets, and by metabolic pathways affecting interaction of chromate-derived reactive species with DNA. Epidemiological data indicate that chromium(VI)
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