123-19-3

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Glycogen Synthase Kinase 3 (GSK-3) Overview

Glycogen synthase kinase 3 (GSK-3) is a highly conserved family of serine/threonine kinases for over 100 proteins in many pathways. See a list of accepted GSK-3 modulators and related products.

MilliporeSigma & Baylor College Covid-19 Collaboration

MilliporeSigma and Baylor College extend collaboration to accelerate Covid-19 manufacturing platform for Phase 1 clinical trials.

Antibiotic Analysis Tetracyclines Sulfonamides Quinolones

LC-MS/MS-based determination of 19 sulfonamides, 13 quinolones, and 3 tetracycline drug residues in pork meat samples using Supel™ Swift HLB for extraction.

Chemical Synthesis of Monodisperse Magnetic Nanoparticles

Magnetic nanoparticles have attracted tremendous attention due to their novel properties and their potential applications in magnetic recording, magnetic energy storage and biomedicine.

Quantum Dots: An Emerging Class of Soluble Optical Nanomaterials

We presents an article concering Quantum Dots: An Emerging Class of Soluble Optical Nanomaterials.

GC Analysis of Omega 3 in Fish Oil and Salmon

Analyze omega 3 fatty acid profiles from fish oil capsules and salmon using GC columns for confirmatory analysis of lipid composition.

5'/3' RACE Kit, 2nd Generation Troubleshooting

In addition to the troubleshooting provided in the product manual, most probably the efficiency of the tailing reaction performed by Terminal Transferase could be impaired. This could occur due to several reasons (which will not only affect the control reaction

The 3'/5' Assay for Analysis of RNA Integrity Protocol

The 3’/5’ integrity assay identifies RNA degradation, crucial for large sample sets or less detectable degradation.

Sample Preparation in Ion Exchange Chromatography

This page clarifies sample preparation, buffer exchange and desalting, removal of lipoproteins, phenol red, and low molecular weight contaminants in Ion exchange chromatography.

MilliporeSigma Supports Jenner Institute to Reach First Milestone in Covid-19 Vaccine

MilliporeSigma and The Jenner Institute today announced that The Jenner Institute has laid the foundation for large-scale production of its Covid-19 vaccine candidate, ChAdOx1 nCoV-19.

Diethanolamine Assay for the Enzymatic Assay of Alkaline Phosphatase (EC 3.1.3.1)

Enzymatic Assay of Alkaline Phosphatase, Diethanolamine Assay (EC 3. 1. 3. 1)

HMG-CoA Reductase (HMGR) Assay Kit

3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) is a transmembrane glycoprotein, located on the endoplasmic reticulum.

MilliporeSigma funds Indian Institute of Technology (IIT) Bombay for Covid-19 research

MilliporeSigma today announced a donation of INR 1.7crore (194,000€) over two years to the Indian Institute of Technology (IIT), Bombay to support the development of clinical tests for Covid-19 disease severity assessment.

MilliporeSigma Supports Eijkman Institute to Expedite Covid-19 Vaccine Development Research

MilliporeSigma today announced the donation of research instruments and materials worth IDR 1.2 billion (€ 74,000) to support the efforts of Eijkman Institute for Molecular Biology, Indonesia.

Materials Design Concepts for Efficient Blue OLEDs: A Joint Theoretical and Experimental Study

Sorting Carbon Nanotubes and Their Biological Applications

Carbon nanotubes (CNTs) have received much attention since their discovery in 1991 by Sumio lijima1 due to their excellent mechanical, electrical, and optical properties.

MILLIPLEX® Multiplex Assays for COVID-19 (SARS-CoV-2) Research Applications

MILLIPLEX® multiplex assays help to better understand the immune response to COVID-19 (SARS-CoV-2), including cytokine storm. Our MILLIPLEX® multiplex immunoassays offer researchers the ability to simultaneously quantitate a large number of analytes critical to understanding the immune response in humans.

Coronavirus COVID-19 (SARS-CoV-2) Detection, Characterization, Vaccine and Therapy Production

We've consolidated our COVID-19 detection, characterization, and vaccine production product offers to help researchers responding to the coronavirus pandemic.

Standard Methods 6040D: GC Analysis of Geosmin and 2-MIB on SLB®-5ms after SPME using 50/30 µm DVB/Carboxen/PDMS Fiber

Separation of 2-Isopropyl-3-methoxypyrazine 20 ppt; 2-Isobutyl-3-methoxypyrazine; 2-Methylisoborneol; (±)-Geosmin 10 ppt

Cholesterol Biosynthesis

Cholesterol biosynthesis starts in the hepatic endoplasmic reticulum with acetyl-CoA, yielding 3-hydroxy-3-methylglutaryl-CoA via HMG-CoA synthase.

Certified Reference Materials for ¹⁹F NMR

Introduction of 19F qNMR certified reference materials for complex molecule certification.

Biopharma Pandemic Learnings: Regulatory Evolution

The Economist Impact report explores COVID-19's effect on biopharma regulatory landscape and collaboration.

Organosilanols

Pd-catalyzed cross-coupling of silicon compounds offers an alternative in synthetic chemistry.

Additional Resources

COVID-19 core products provide specialized tools for virus detection, immunological analysis, and biosafety solutions.

Cultrex ® 3-D Culture Matrix™ Laminin I Protocol

3-D Culture Matrix™ Mouse Laminin I may be used as a gel or as a media additive to study cellular growth and differentiation in three dimensions in vitro.

MilliporeSigma Partners with Promega to Advance 3-D Cell Drug Discovery Technologies

MilliporeSigma and Promega will co-develop novel technologies that advance drug discovery.

Microscopic Examination of Samples

This protocol covers 3 modes for the microscopic examination of cell samples.

Metrangolo Group – Prof. Product Portal

Metrangolo Group develops cellular-compatible contrast agent for in vivo 19F-MRI applications.

Graphene and New Monoatomic Materials: Using 2-Dimensional Nanosheets in a 3-Dimensional World

Isotopic Labeling for NMR Spectroscopy of Biological Solids

Isotopic Labeling for NMR Spectroscopy of Biological Solids;

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123-19-3

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