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Vincenzo Torraca et al.
Disease models & mechanisms, 8(3), 253-269 (2015-01-13)
The recruitment of leukocytes to infectious foci depends strongly on the local release of chemoattractant mediators. The human CXC chemokine receptor 3 (CXCR3) is an important node in the chemokine signaling network and is expressed by multiple leukocyte lineages, including
Werner E G Müller et al.
Marine drugs, 10(11), 2369-2387 (2012-12-04)
Adhesion and accumulation of organic molecules represent an ecologically and economically massive problem. Adhesion of organic molecules is followed by microorganisms, unicellular organisms and plants together with their secreted soluble and structure-associated byproducts, which damage unprotected surfaces of submerged marine
Joshua Schindel et al.
International journal of radiation oncology, biology, physics, 86(2), 387-393 (2013-02-26)
To present a novel marker-flange, addressing source-reconstruction uncertainties due to the artifacts of a titanium intracavitary applicator used for magnetic resonance imaging (MRI)-guided high-dose-rate (HDR) brachytherapy (BT); and to evaluate 7 different MRI marker agents used for interstitial prostate BT
Eun Ji Lee et al.
Nephrology (Carlton, Vic.), 19(8), 471-478 (2014-04-15)
Autosomal dominant polycystic kidney disease (ADPKD) is a highly prevalent inherited disorder and results in the progressive development of cysts in both kidneys. In recent studies, several cytokines and growth factors secreted by the cyst-lining epithelia were identified to be
C Tarhan et al.
Genetics and molecular research : GMR, 11(4), 3824-3834 (2012-11-13)
Because of its specific electrochemical properties, copper is an essential heavy metal for living organisms. As with other heavy metals, high levels can provoke damage. We examined gene expression under copper stress in wild-type fission yeast (Schizosaccharomyces pombe) through differential
Gloria Isani et al.
Ecotoxicology and environmental safety, 97, 40-46 (2013-08-13)
This study compared the toxicity and accumulation of two different Cu compounds, CuO nanoparticles (NPs) and soluble CuSO4, in erythrocytes and different tissues in rainbow trout (Oncorhynchus mykiss). The crystal structure of CuO NP analysed by XRD indicates that the
A Radhika et al.
Molecular and cellular biochemistry, 372(1-2), 181-190 (2012-10-12)
Formation of foam cells from macrophages, which are formed by the differentiation of blood-borne monocytes, is a critical early event in atherogenesis. To examine how pre-exposure of monocytes to modified proteins, such as oxLDL, influences their differentiation to macrophages, an
Bogdan I Tamba et al.
Journal of neuroscience research, 91(4), 554-561 (2013-01-31)
Trace elements represent a group of essential metals or metaloids necessary for life, present in minute amounts. Analgesic adjuvants can enhance the effect of other pain drugs or be used for pain control themselves. Previous studies on the effects of
Eleftherios A Makris et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(6), 2421-2430 (2013-03-05)
The objective of this study was to improve the biomechanical properties of engineered neotissues through promoting the development of collagen cross-links. It was hypothesized that supplementing medium with copper sulfate and the amino acid hydroxylysine would enhance the activity of
Qiong Dai et al.
ACS nano, 9(3), 2876-2885 (2015-02-26)
Engineered particles adsorb biomolecules (e.g., proteins) when introduced in a biological medium to form a layer called a "corona". Coronas, in particular the protein corona, play an important role in determining the surface properties of particles and their targeting abilities.
J Higny et al.
Acta clinica Belgica, 69(4), 299-301 (2014-05-23)
Bluish vomiting is a symptom of poisoning that is rarely seen in Western emergency departments. Consequently, physicians are not aware of the diagnosis, complications, and treatment of this unusual form of intoxication. In this article, we report a case of
Andrew C Holloway et al.
Metallomics : integrated biometal science, 4(12), 1280-1286 (2012-11-10)
Few attempts have been made to improve the activity of plant compounds with low antimicrobial efficacy. (+)-Catechin, a weak antimicrobial tea flavanol, was combined with putative adjuncts and tested against different species of bacteria. Copper(II) sulphate enhanced (+)-catechin activity against
Ashlie Watters et al.
Biofouling, 29(1), 21-28 (2012-12-01)
Quagga mussels (Dreissena rostriformis bugensis) have created economic and ecological impacts in the western United States since their discovery in 2007. This study focuses on chemical control for preventing the spread of these mussels. The effectiveness of EarthTec(®) in killing
Hao Feng et al.
Plant molecular biology, 83(4-5), 433-443 (2013-07-19)
microRNAs (miRNAs) are novel and significant regulators of gene expression at the post-transcriptional level, and they are essential for normal growth and development and adaptation to stress conditions. As miRNAs are a kind of RNAs that do not code proteins
Pieter Spincemaille et al.
Toxicology and applied pharmacology, 280(2), 345-351 (2014-08-20)
Wilson disease (WD) is caused by accumulation of excess copper (Cu) due to a mutation in the gene encoding the liver Cu transporter ATP7B, and is characterized by acute liver failure or cirrhosis and neuronal cell death. We investigated the
Mehri Haeili et al.
Antimicrobial agents and chemotherapy, 58(7), 3727-3736 (2014-04-23)
Macrophages take advantage of the antibacterial properties of copper ions in the killing of bacterial intruders. However, despite the importance of copper for innate immune functions, coordinated efforts to exploit copper ions for therapeutic interventions against bacterial infections are not
Nilantha P Wickramaratne et al.
Langmuir : the ACS journal of surfaces and colloids, 29(12), 4032-4038 (2013-03-07)
A series of cysteine-stabilized phenolic resin-based polymer and carbon spheres were prepared by the modified Stöber method. Cysteine plays a very important role in the proposed one-pot synthesis of the aforementioned spheres; namely, it acts as a particle stabilizer and
Hao Wei et al.
Redox report : communications in free radical research, 19(1), 40-48 (2013-11-15)
Endothelial activation with increased expression of cellular adhesion molecules and chemokines critically contributes to vascular inflammation and atherogenesis. Redox-active transition metal ions play an important role in vascular oxidative stress and inflammation. Therefore, the goal of the present study was
Leila Lo Leggio et al.
Nature communications, 6, 5961-5961 (2015-01-23)
Lytic polysaccharide monooxygenases (LPMOs) are recently discovered enzymes that oxidatively deconstruct polysaccharides. LPMOs are fundamental in the effective utilization of these substrates by bacteria and fungi; moreover, the enzymes have significant industrial importance. We report here the activity, spectroscopy and
Damijana Urankar et al.
Journal of combinatorial chemistry, 10(6), 981-985 (2008-10-17)
Azoamides, previously established as bioactive intracellular GSH-depleting agents, were decorated with a terminal alkyne moiety to 4 and then were transformed, by copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC), into different ligand-arm functionalized azoamides 6. Azides 5 having ligand-arms amenable for binding to
Lucian Beer et al.
Scientific reports, 5, 16662-16662 (2015-11-17)
We previously showed that, when peripheral blood mononuclear cells (PBMCs) were stressed with ionizing radiation, they released paracrine factors that showed regenerative capacity in vitro and in vivo. This study aimed to characterize the secretome of PBMCs and to investigate
Hong Miao et al.
Nanoscale, 7(45), 19066-19072 (2015-10-31)
Herein, papain-functionalized Cu nanoclusters (CuNCs@Papain) were originally synthesized in aqueous solution together with a quantum yield of 14.3%, and showed obviously red fluorescence at 620 nm. Meanwhile, their corresponding fluorescence mechanism was fully elucidated by fluorescence spectroscopy, HR-TEM, FTIR spectroscopy
Preparation of Cu2ZnSnS4 thin films by sulfurization of co-electroplated Cu-Zn-Sn precursors.
Araki H, et al.
Physica Status Solidi, 6(5), 1266-1268 (2009)
Tereza Sovová et al.
Aquatic toxicology (Amsterdam, Netherlands), 152, 195-204 (2014-05-06)
To date, studies of the toxicity of engineered nanoparticles (NPs) in fish have not fully considered effects on olfactory-mediated behaviours, despite their ecological importance. In this study the effects of copper NPs (Cu NPs) on the anti-predator behavioural responses of
Genan A Al-Bairuty et al.
Aquatic toxicology (Amsterdam, Netherlands), 126, 104-115 (2012-11-24)
It is unclear whether copper nanoparticles are more toxic than traditional forms of dissolved copper. This study aimed to describe the pathologies in gill, gut, liver, kidney, brain and muscle of juvenile rainbow trout, Oncorhynchus mykiss, exposed in triplicate to
William T Triplett et al.
Magnetic resonance in medicine, 72(1), 8-19 (2013-09-06)
The relationship between fat fractions (FFs) determined based on multiple TE, unipolar gradient echo images and (1) H magnetic resonance spectroscopy (MRS) was evaluated using different models for fat-water decomposition, signal-to-noise ratios, and excitation flip angles. A combination of single-voxel
T P Pirog et al.
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993), 75(5), 18-26 (2014-02-01)
The effect of yeast autolysate and microelements on synthesis of surface-active substances (SAS, biosurfactants) was investigated under cultivation of Acinetobacter calcoaceticus IMV B-7241 on various carbon substrates (n-hexadecane, ethanol, glycerol). The authors have shown a possibility to substitute the yeast
Marcel Prax et al.
Journal of microbiological methods, 118, 176-181 (2015-10-13)
Sodium polyanethol sulfonate (SPS) is an anionic detergent with a broad range of activities and applications. While studying the excretion of cytoplasmic proteins in Staphylococcus aureus SPS was used as cell lysis inhibitor. When investigating the protein pattern of culture
Guillaume Cormier et al.
Environmental science. Processes & impacts, 17(12), 2051-2065 (2015-11-14)
An increasing diversity of emerging contaminants are entering urban surface water and wastewater, posing unknown risks for the environment. One of the main contemporary challenges in ensuring water quality is to design efficient strategies for minimizing such risks. As a
Palaniappan Subramanian et al.
The Analyst, 139(17), 4343-4349 (2014-07-11)
Coating boron-doped diamond nanowires (BDD NWs) with a conducting polymer, poly[3-(pyrrolyl)carboxylic acid], has been reported. Polymer coating was achieved through electropolymerization of 3-(pyrrolyl)carboxylic acid at the electrode interface by amperometrically biasing the BDD NWs interface until a predefined charge has
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