136-40-3

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Glycogen Synthase Kinase 3 (GSK-3) Overview

Glycogen synthase kinase 3 (GSK-3) is a highly conserved family of serine/threonine kinases for over 100 proteins in many pathways. See a list of accepted GSK-3 modulators and related products.

Column Packing and Preparation for Size Exclusion Chromatography

The 3'/5' Assay for Analysis of RNA Integrity Protocol

The 3’/5’ integrity assay identifies RNA degradation, crucial for large sample sets or less detectable degradation.

GC Analysis of Omega 3 in Fish Oil and Salmon

Analyze omega 3 fatty acid profiles from fish oil capsules and salmon using GC columns for confirmatory analysis of lipid composition.

5'/3' RACE Kit, 2nd Generation Troubleshooting

In addition to the troubleshooting provided in the product manual, most probably the efficiency of the tailing reaction performed by Terminal Transferase could be impaired. This could occur due to several reasons (which will not only affect the control reaction

Diethanolamine Assay for the Enzymatic Assay of Alkaline Phosphatase (EC 3.1.3.1)

Enzymatic Assay of Alkaline Phosphatase, Diethanolamine Assay (EC 3. 1. 3. 1)

Superoxide Dismutase

Enzyme Explorer Product Application Index for Superoxide Dismutase offered by us online. Superoxide Dismutase (SOD) catalyzes the reduction of superoxide anions to hydrogen peroxide.

HMG-CoA Reductase (HMGR) Assay Kit

3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) is a transmembrane glycoprotein, located on the endoplasmic reticulum.

Standard Methods 6040D: GC Analysis of Geosmin and 2-MIB on SLB®-5ms after SPME using 50/30 µm DVB/Carboxen/PDMS Fiber

Separation of 2-Isopropyl-3-methoxypyrazine 20 ppt; 2-Isobutyl-3-methoxypyrazine; 2-Methylisoborneol; (±)-Geosmin 10 ppt

Fast LC-MS-MS Analysis of 25-Hydroxyvitamin D2 and 25-Hydroxyvitamin D3

We presents a robust method for analyzing 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 in serum using a multiplexed LC-MS-MS system.

Cholesterol Biosynthesis

Cholesterol biosynthesis starts in the hepatic endoplasmic reticulum with acetyl-CoA, yielding 3-hydroxy-3-methylglutaryl-CoA via HMG-CoA synthase.

Summer Sale Promo - Cell Culture

Spend your summer accelerating your Cell Culture research. Now through July 29, save up to 40% off our most popular Cell Culture products

Ultra-High Efficiency Perovskite-Perovskite Tandem Solar Cells

Next generation solar cells have the potential to achieve conversion efficiencies beyond the Shockley-Queisser (S-Q) limit while also significantly lowering production costs.

Cultrex ® 3-D Culture Matrix™ Laminin I Protocol

3-D Culture Matrix™ Mouse Laminin I may be used as a gel or as a media additive to study cellular growth and differentiation in three dimensions in vitro.

MilliporeSigma Partners with Promega to Advance 3-D Cell Drug Discovery Technologies

MilliporeSigma and Promega will co-develop novel technologies that advance drug discovery.

Microscopic Examination of Samples

This protocol covers 3 modes for the microscopic examination of cell samples.

Graphene and New Monoatomic Materials: Using 2-Dimensional Nanosheets in a 3-Dimensional World

Life Science Business of Merck KGaA, Darmstadt, Germany Study: mRNA Technology a ‘Game Changer’ for Asia-Pacific Vaccine Manufacturers

According to a recent study sponsored by the Life Science business of Merck KGaA, Darmstadt, Germany, mRNA technology is a “game-changer” for Asia-Pacific (APAC) vaccine manufacturers. Nearly 40 manufacturers participated in the survey.

Cultrex® 3-D Culture Matrix™ Rat Collagen I Protocol

3-D Culture Matrix™ Collagen I facilitates cellular growth and differentiation in vitro, offering versatile applications in biomedical research.

What You Need to Know About the New ISO 16140-3 Microbiological Method Verification

This on-demand webinar introduces the new EN ISO 16140-3 on the verification of methods in food microbiology.

Polymer Semiconductors for Intrinsically Stretchable Organic Transistors

Intrinsically stretchable active layers for organic field-effect transistors (OFET) are discussed. Polymer structural modification & post-polymerization modifications are 2 methods to achieve this.

Troubleshooting first-dimension IEF: Ettan™ IPGphor™ 3 Isoelectric Focusing System

Troubleshooting first-dimension isoelectric focusing with Ettan IPGphor 3 Isoelectric Focusing System from Cytiva.

Differentiation of Primary Human Osteoblasts

Cell culture protocol used to differentiate primary human osteoblasts into bone cells in 2-3 weeks.

Enzymatic Assay of Peroxidase (EC 1.11.1.7) 2,2'-Azino-bis(3-Ethylbenzthiazoline-6-Sulfonic Acid) as a Substrate

To standardize a procedure for the assay of Peroxidase using 2,2'-Azino-bis(3-Ethylbenzthiazoline-6-Sulfonic Acid) as a substrate.

Determination of Water Content in Ethyl acetate, acetic acid ethyl ester Using Karl Fischer Titration

Accurately measure moisture content in ethyl acetate (CH3CO2CH2CH3) through Karl Fischer titration, using both volumetric and coulometric methods for reliable results.

Antibiotic Analysis Tetracyclines Sulfonamides Quinolones

LC-MS/MS-based determination of 19 sulfonamides, 13 quinolones, and 3 tetracycline drug residues in pork meat samples using Supel™ Swift HLB for extraction.

Mole Day 2021 Thank You

Mole Day is October 23 (1023), in honor of Avogadro's Number. Solve the chemistry problem below and win an awesome pair of Mole Day socks while supplies last. Coming soon! Save up to 40% on select chemistry products October 18

Custom siRNA Design Service Request Form

Please fill out the form to receive a complimentary siRNA design. Requests are typically completed within 3 working days.

Nanoparticle-Based Drug and Gene Delivery for Tumor Targeting

Professor Yoshiki Katayama (Kyushu University, Japan) discusses recent advances in drug delivery systems and strategies that exploit the EPR effect, with a special focus on stimuli-responsive systems based on novel materials.

Viral Safety in Bioprocessing

Viral safety in bioprocessing relies on a framework of (1) preventing contamination, (2) detecting contamination, and (3) removing or inactivating viral contaminants.

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