Showing 1-12 of 12 results for "13767"
Preparation of xylenol orange functionalized silica gel as a selective solid phase extractor and its application for preconcentration?separation of mercury from waters
Fan J, et al.
Journal of Hazardous Materials, 145(1), 323-330 (2007)
Qingyu Zhang et al.
Brain, behavior, and immunity, 88, 471-481 (2020-04-14)
Increased kynurenine (Kyn) metabolized from tryptophan (Try) is a biomarker in the immune dysfunction of depression. However, the mechanism by which Kyn change promotes depression is poorly defined. Astrocytes are involved in the neuroinflammation of depression. Among the numerous inflammatory...
Holger Erfle et al.
Journal of biomolecular screening, 13(7), 575-580 (2008-07-05)
Solid-phase reverse transfection on cell microarrays is a high-throughput method for the parallel transfection of mammalian cells. However, the cells transfected in this way have been restricted so far to microscopy-based analyses. Analysis methods such as reverse transcriptase-polymerase chain reaction...
Holger Erfle et al.
Nature protocols, 2(2), 392-399 (2007-04-05)
Here, we describe a robust protocol for the reverse transfection of cells on small interfering (siRNA) arrays, which, in combination with multi-channel immunofluorescence or time-lapse microscopy, is suitable for genome-wide RNA interference (RNAi) screens in intact human cells. The automatic...
Holger Erfle et al.
Methods in molecular biology (Clifton, N.J.), 785, 277-287 (2011-09-09)
Endocytosis is one of the most essential cellular processes, which enables cells to internalise diverse -material. It is crucial for regulation of receptor activity and signalling, cell polarisation, attachment and motility, and a great number of other cellular functions. A...
Metal ion enrichment with Amberlite XAD-2 functionalized with Tiron: analytical applications
Kumar M, et al.
Analyst, 125(6), 1221-1226 (2000)
Miaomiao Jia et al.
The international journal of neuropsychopharmacology, 20(11), 886-895 (2017-10-11)
Leonurine is an active alkaloid that is extracted from Traditional Chinese Medicine Herba leonuri. Emerging evidence indicates that leonurine produces neuroprotective effects in ischemic stroke, Parkinson's disease, and Alzheimer's disease. However, the effect of leonurine in neuropsychiatric disorders, especially in...
Jialei Zhu et al.
Brain, behavior, and immunity, 90, 259-271 (2020-08-31)
Activated astrocytes secrete inflammatory cytokines such as interleukin-1β (IL-1β) into the extracellular milieu, damaging surrounding neurons and involving in the pathogenesis of neurodegenerative diseases, such as Parkinson's disease (PD). Dopamine receptor D2 (Drd2) expresses both in neurons and astrocytes, and...
Yojana J P Carreón et al.
Scientific reports, 8(1), 9580-9580 (2018-06-27)
The deposit patterns derived from droplet evaporation allow current development of medical tests and new strategies for diagnostic in patients. For such purpose, the development and implementation of algorithms capable of characterizing and differentiating deposits are crucial elements. We report...
Ren-Wei Du et al.
Experimental brain research, 238(11), 2549-2556 (2020-09-02)
Emerging evidence indicates that NLRP3 inflammasome-induced inflammation plays a crucial role in the pathogenesis of depression. Thus, inhibition of NLRP3 inflammasome activation may offer a therapeutic benefit in the treatment of depression. Metformin has been shown to have potential anti-inflammatory...
Jialei Zhu et al.
Cell death and differentiation, 25(11), 2037-2049 (2018-05-23)
Astrocytes are involved in the neuroinflammation of neurodegenerative diseases, such as Parkinson's disease (PD). Among the numerous inflammatory cytokines, interleukin-1β (IL-1β) produced by astrocytic Nod-like receptor protein (NLRP) inflammasome is crucial in the pathogenesis of PD. β-arrestin2-mediated dopamine D2 receptor...
Komaraiah Palle et al.
The Journal of biological chemistry, 283(41), 27767-27775 (2008-08-12)
In eukaryotes, DNA topoisomerase I (Top1) catalyzes the relaxation of supercoiled DNA by a conserved mechanism of transient DNA strand breakage, rotation, and religation. The unusual architecture of the monomeric human enzyme comprises a conserved protein clamp, which is tightly...

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