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139386

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Anna Kiyomi et al.
Journal of Cancer, 6(4), 367-376 (2015-03-15)
Aromatase inhibitor use for postmenopausal hormone-sensitive breast cancer patients often results in drug-induced osteoarthropathy, while its accurate mechanism has not been clarified. We investigated the implication of female hormones and several cytokines in osteoarthropathy complicated with aromatase inhibitor treatment, and...
Zhenchang Liang et al.
PloS one, 9(8), e105146-e105146 (2014-08-19)
Grapes are rich in phytochemicals with many proven health benefits. Phenolic profiles, antioxidant and antiproliferative activities of twenty-four selected Vitis vinifera grape cultivars were investigated in this study. Large ranges of variation were found in these cultivars for the contents...
Wenfen Zhang et al.
Journal of agricultural and food chemistry, 62(26), 6100-6107 (2014-06-17)
In this paper, a rapid and effective HPLC method, using tetraazacalix[2]arene[2]triazine-modified silica gel (NCSi) as solid-phase extraction (SPE) sorbent, was developed for the purification and determination of trace acrylamide in starchy foodstuffs. The main influence factors of SPE including amount...
Stephen W C Chung et al.
Journal of agricultural and food chemistry, 62(25), 5805-5811 (2014-06-06)
This paper reports the development of a method for the quantitative analysis of perfluorinated compounds (PFCs), including C6-C14 perfluorinated carboxylic acids (PFCAs) and C4-C12 perfluorinated sulfonates (PFSAs), in fish and fatty foods by ultraperformance liquid chromatography-electrospray ionization-tandem mass spectrometry (UPLC-ESI-MS/MS)...
Bruna L Lima Maciel et al.
PloS one, 9(9), e107564-e107564 (2014-10-01)
Vitamin A supplementation has shown to prevent mortality by diarrheal and respiratory diseases in several countries. Nevertheless, there are few studies investigating the effect of vitamin A in visceral leishmaniasis (VL), although there are reports of its deficiency in children...
Rick W Fedeniuk et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 983-984, 1-9 (2015-01-24)
Separate methods for the quantitation and confirmation of regulatory relevant residue concentrations of total florfenicol and tulathromycin residues in multiple tissue matrices were developed and validated. Total florfenicol residues, determined and expressed as florfenicol amine (FFA) equivalents, were quantified and...
Shigeo Hayashi et al.
Journal of enzyme inhibition and medicinal chemistry, 29(6), 846-867 (2014-02-13)
Because of the pivotal role of cyclooxygenase (COX) in the inflammatory processes, non-steroidal anti-inflammatory drugs (NSAIDs) that suppress COX activities have been used clinically for the treatment of inflammatory diseases/syndromes; however, traditional NSAIDs exhibit serious side-effects such as gastrointestinal damage...
Nobuyasu Hanari et al.
Analytical and bioanalytical chemistry, 407(11), 3239-3247 (2015-02-07)
Certified reference materials (CRMs) are playing an increasingly important role in national and international standardizing activities. In Japan, primary standard solutions for analyses of endocrine disrupters are supplied under the national standards dissemination system named the Japan Calibration Service System...
Rika Homma et al.
Journal of agricultural and food chemistry, 63(46), 10161-10169 (2015-10-28)
The impact of association colloids on lipid oxidation in triacylglycerols and fatty acid ethyl esters was investigated. Association colloids did not affect lipid oxidation of high oleic safflower and high linoleic safflower triacylglycerols, but were prooxidative in fish triacylglycerols. Association...
Lilian C Hsiao et al.
Nature communications, 6, 8507-8507 (2015-10-08)
The interplay between phase separation and kinetic arrest is important in supramolecular self-assembly, but their effects on emergent orientational order are not well understood when anisotropic building blocks are used. Contrary to the typical progression from disorder to order in...
Anne-Kathrin Siemers et al.
Chemosphere, 122, 105-114 (2014-12-09)
Polycyclic aromatic hydrocarbons (PAHs), heterocyclic PAHs (NSO-HETs), alkylated PAHs and phenols are known as the prevailing contaminants in groundwater at tar contaminated sites. Besides these local sources, the concentrations and the distribution in particular of NSO-HETs in environmental samples, such...
Ahmed M Zeitoun et al.
Biotechnology progress, 30(5), 992-1004 (2014-08-01)
Over the last decades, the cultivation of fibrous flax declined heavily. There are number of reasons for that fact; one of them is flax susceptibility to the pathogen infection. Damages caused mainly by fungi from genus Fusarium lead to the...
Diana L Shuster et al.
The Journal of pharmacology and experimental therapeutics, 350(2), 425-434 (2014-06-06)
Gestational diabetes mellitus is a major complication of human pregnancy. The oral clearance (CL) of glyburide, an oral antidiabetic drug, increases 2-fold in pregnant women during late gestation versus nonpregnant controls. In this study, we examined gestational age-dependent changes in...
Haisung Lee et al.
International journal of nanomedicine, 10 Spec Iss, 215-225 (2015-09-12)
In this study, fluorescent dye-conjugated magnetic resonance (MR) imaging agents were investigated in T mode. Gadolinium-conjugated silica nanoparticles were successfully synthesized for both MR imaging and fluorescence diagnostics. Polyamine and polycarboxyl functional groups were modified chemically on the surface of...
Carmen Estevan et al.
Journal of occupational and environmental hygiene, 9(11), 653-662 (2012-09-29)
This study measured inhalation exposure to 13 volatile organic compounds (VOCs) among workers in the leatherwear industry in Spain, examined the changes in those exposures over a 5-year period, and documented local exhaust ventilation practices that affected exposure. In collaboration...
Da-Hye Kim et al.
Environmental pollution (Barking, Essex : 1987), 192, 171-178 (2014-06-24)
Serum and urine samples from 120 children aged 5-13 years from Dae-gu, Korea, were analyzed for 16 perfluorinated compounds (PFCs). The total PFC concentrations in the serum were 4.26-29.70 ng/mL, and perfluorohexanesulfonate (PFHxS), perfluorooctanoic acid (PFOA), perfluorooctanesulfonate (PFOS, which was dominant...
Janine Winkler et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 32(3), 371-380 (2015-04-08)
A dose-response study was carried out to examine the carryover of zearalenone (ZEN), deoxynivalenol (DON) and their metabolites into bovine milk. Therefore, a feeding trial with 30 dairy cows fed with three different levels of Fusarium (FUS) toxin-contaminated maize was...
Agnieszka Kucharska et al.
The Science of the total environment, 505, 1062-1071 (2014-12-03)
In this study, we investigated the hypothesis whether externally adsorbed and internally deposited flame retardants (FRs) in hair could be distinguished. To this extent, hair samples collected from one volunteer were exposed under controlled conditions to phosphate FR (PFR) and...
Anantha Peramuna et al.
Life (Basel, Switzerland), 5(2), 1111-1126 (2015-03-31)
Cyanobacterial lipid droplets (LDs) are packed with hydrophobic energy-dense compounds and have great potential for biotechnological expression and the compartmentalization of high value compounds. Nostoc punctiforme normally accumulates LDs containing neutral lipids, and small amounts of heptadecane, during the stationary...
Prachi Kakkar et al.
Materials science & engineering. C, Materials for biological applications, 45, 343-347 (2014-12-11)
Keratin has gained much attention in the recent past as a biomaterial for wound healing owing to its biocompatibility, biodegradability, intrinsic biological activity and presence of cellular binding motifs. In this paper, a novel biomimetic scaffold containing keratin, chitosan and...
Immacolata Porreca et al.
BMC genomics, 15, 1067-1067 (2014-12-06)
Comparison of toxicogenomic data facilitates the identification of deregulated gene patterns and maximizes health risk prediction in human. Here, we performed phenotypic anchoring on the effects of acute exposure to low-grade polluted groundwater using mouse and zebrafish. Also, we evaluated...
Fengchun Zhao et al.
Analytical and bioanalytical chemistry, 407(30), 8959-8970 (2015-10-03)
To develop a broad-specificity immunoassay for organophosphorus pesticides (OPs), a broad-specificity monoclonal antibody (MAb) for OPs against a generic hapten, O,O-diethyl O-(3-carboxyphenyl) phosphorothioate with the carboxy group in the meta position of the benzene ring, was produced. Eight haptens were...
Mwafaq Ibdah et al.
Phytochemistry, 107, 24-31 (2014-08-26)
The apple tree (Malus sp.) is an agriculturally and economically important source of food and beverages. Many of the health beneficial properties of apples are due to (poly)phenolic metabolites that they contain, including various dihydrochalcones. Although many of the genes...
Ravi Rapolu et al.
Journal of pharmaceutical and biomedical analysis, 99, 59-66 (2014-07-30)
Forced degradation of Amlodipine Besylate (AMD) in acidic condition gave rise to a potential unknown impurity. This unknown acid degradation product (ADP) was evaluated using a new-reverse-phase high performance liquid chromatography (HPLC), where it was eluted at 1.24 relative retention...
Jadwiga C Wojtowicz et al.
Experimental eye research, 127, 261-269 (2014-08-26)
The aim of this prospective study was to conduct histopathologic and lipidomic analyses of chalazia, in order to evaluate time-dependent changes in the lesion. Samples of surgically excised chalazia were collected over a period of 12 months from 10 patients (mean age...
Abdelmonaim Azzouz et al.
Food chemistry, 178, 63-69 (2015-02-24)
A sensitive, selective, efficient gas chromatography-mass spectrometry method for the simultaneous determination of 22 pharmacologically active substances (antibacterials, nonsteroidal antiinflammatories, antiseptics, antiepileptics, lipid regulators, β-blockers and hormones) in eggs and honey was developed. The sample pretreatment includes precipitation of proteins...
Agung Endro Nugroho et al.
Asian Pacific journal of cancer prevention : APJCP, 13(11), 5785-5790 (2013-01-16)
The use of chemotherapeutics induces cardiotoxicity and affects immune functions, therefore development of combinatorial agents against cardiotoxicity and immunosuppression needs to be explored. Previous studies of the hexane insoluble fraction (HIF) of an ethanolic extract of Ficus septica leaves showed...
Cynthia K Colapinto et al.
Environmental research, 142, 77-83 (2015-06-29)
Pesticide residues in tea may contribute to exposure during pregnancy; however, the impact on maternal and infant health is not well understood. The aim of this study was to determine whether tea intake in the first trimester was associated with...
Francesca Mangialasche et al.
Journal of Alzheimer's disease : JAD, 44(2), 649-660 (2014-10-18)
Specific mechanisms behind the role of oxidative/nitrosative stress and mitochondrial dysfunction in Alzheimer's disease (AD) pathogenesis remain elusive. Mitochondrial aconitase (ACO2) is a Krebs cycle enzyme sensitive to free radical-mediated damage. We assessed activity and expression of ACO2 extracted from...
Yuanzhi Chen et al.
Small (Weinheim an der Bergstrasse, Germany), 11(12), 1460-1469 (2014-10-31)
The combination of metal and semiconductor components in nanoscale to form a hybrid nanocrystal provides an important approach for achieving advanced functional materials with special optical, magnetic and photocatalytic functionalities. Here, a facile solution method is reported for the synthesis...
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