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Showing 1-10 of 30 results for "14380CSIGMA" within Site Content
High Performing Platforms for Lentivirus and AAV Manufacturing
Upstream gene therapy optimization maximizes viral vector titers; partner with technology experts for HEK293, HEK293T, and Sf9 cell solutions.
Can AAV Continue to Deliver the Promise of Gene Therapy?
The current status and future manufacturing of AAV-based gene therapies is discussed in this podcast transcript, including how to streamline large-scale manufacturing.
Cell and Gene Therapy Manufacturing: Upstream Processing for AAV and Lentivirus Platforms
Minimize the complexities of cell and gene therapy production. Switch to upstream viral vector platforms to enhance scalability and simplify GMP manufacturing.
Viral Vector Upstream Platforms
A transfection-based solution to viral vector production using a suspension cell line, chemically defined medium, and a process with proven performance at scale.
Plataformas ascendentes de vectores virales
Una solución basada en transfección para la producción de vectores virales utilizando una línea celular en suspensión, un medio químicamente definido y un proceso con un rendimiento probado a gran escala.
Building Regional Cell Culture Media Supply Chains
Ensure reliable cell culture media supply with our continuously expanding global network of regional sites for resilient biopharma manufacturing.
Virus-like Particle (VLP) Vaccine Bioprocessing and Formulation Steps
This technical article breaks down the steps of upstream and downstream bioprocessing and formulation of virus-like particle vaccines.
Using Microarray Technology to Select Housekeeping Genes in Chinese Hamster Ovary Cells
In the present study, we have identifi ed species-specifi c housekeeping genes (HKGs) for Chinese Hamster Ovary (CHO) cells using data from microarray gene expression profiling.
Mgat4 May Play a Role in Increased Sialylation by Overexpressing Functional MGAT1 in Mgat1-Disrupted Chinese Hamster Ovary (CHO) Cells
MGAT1 adds N-acetylglucosamine to the Man5GlcNAc2 (Man5) structure. Goh et al. reported increased sialylation after restoring MGAT1 function in MGAT1 deficient CHO cells.
Signal Peptide Optimization: Effect On Recombinant Monoclonal IgG Productivity, Product Quality And Antigen-Binding Affinity
A signal peptide is a 5-30 amino acid (aa) peptide present at the N-terminus of secretory proteins.
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