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Showing 1-29 of 29 results for "14390CSIGMA" within Site Content
Cell Line Development for mAbs
Learn more about cell line development and the relevant products you need for this process.
Cell Culture Media Development for mAbs
Learn more about cell culture media development for mAB development and manufacturing, and the products you need for this step.
CHO Media and Feeds for Optimized Production of Therapeutic Proteins
Cellvento® and EX-CELL® CHO cell culture media and feeds, optimized for monoclonal antibody & recombinant protein production in fed-batch & perfusion
Using Microarray Technology to Select Housekeeping Genes in Chinese Hamster Ovary Cells
In the present study, we have identifi ed species-specifi c housekeeping genes (HKGs) for Chinese Hamster Ovary (CHO) cells using data from microarray gene expression profiling.
Mgat4 May Play a Role in Increased Sialylation by Overexpressing Functional MGAT1 in Mgat1-Disrupted Chinese Hamster Ovary (CHO) Cells
MGAT1 adds N-acetylglucosamine to the Man5GlcNAc2 (Man5) structure. Goh et al. reported increased sialylation after restoring MGAT1 function in MGAT1 deficient CHO cells.
Signal Peptide Optimization: Effect On Recombinant Monoclonal IgG Productivity, Product Quality And Antigen-Binding Affinity
A signal peptide is a 5-30 amino acid (aa) peptide present at the N-terminus of secretory proteins.
High Performing Platforms for Lentivirus and AAV Manufacturing
Upstream gene therapy optimization maximizes viral vector titers; partner with technology experts for HEK293, HEK293T, and Sf9 cell solutions.
Can AAV Continue to Deliver the Promise of Gene Therapy?
The current status and future manufacturing of AAV-based gene therapies is discussed in this podcast transcript, including how to streamline large-scale manufacturing.
Cell and Gene Therapy Manufacturing: Upstream Processing for AAV and Lentivirus Platforms
Minimize the complexities of cell and gene therapy production. Switch to upstream viral vector platforms to enhance scalability and simplify GMP manufacturing.
Building Regional Cell Culture Media Supply Chains
Ensure reliable cell culture media supply with our continuously expanding global network of regional sites for resilient biopharma manufacturing.
Viral Vector Upstream Platforms
A transfection-based solution to viral vector production using a suspension cell line, chemically defined medium, and a process with proven performance at scale.
Plataformas ascendentes de vectores virales
Una solución basada en transfección para la producción de vectores virales utilizando una línea celular en suspensión, un medio químicamente definido y un proceso con un rendimiento probado a gran escala.
Cell Lines for Recombinant Protein Expression
Eukaryotic cell lines aid in complex post-translational modifications and folding of recombinant proteins. Find suitable recombinant protein production cell lines.
Optimizing CHO Cells for Higher Productivity
Cellvento 4CHO-X Expansion Medium enhances cell biomass for bioreactor inoculation in cell expansion stages.
Development and Optimization of a Lentivirus Manufacturing Platform
Learn how development of a suspension adapted HEK293T cell line with accompanying cell culture media can maximize lentivirus production for cell and gene therapies.
Upstream Bioprocessing Feed Strategies and Scalability: A Case Study with Cellvento® ModiFeed Prime COMP
This case study walks through optimizing feed and media for upstream bioprocessing and how it translates to large-scale bioreactors.
EX-CELL® Advanced™ CHO Fed-Batch System – Bioprocessing Technology Institute, Singapore Case Study
In this study, nine commercially available, chemically defined media and feed combinations from different vendors were assessed for producing monoclonal antibody in Chinese hamster ovary (CHO) cells.
Bioreactor Process Development and Scale-Up for Transient Transfection-Based Lentivirus Manufacturing in Suspension Cell Culture
A step-by-step overview of suspension-based, transient transfection bioreactor process development and scaleup of lentivirus production.
Scalability Challenges of Viral Vector Manufacturing
Scaling up viral vector production using adherent cell culture systems is challenging. Learn how suspension cell culture systems benefit large-scale bioprocessing.
Low-Impurity Iron Sources: Case Studies in EX-CELL® Advanced Medium
Discover how low-impurity iron sources improve reliability and performance in recombinant protein production with EX-CELL® Advanced medium.
Bioprocessing And Scale-Up Of Suspension HEK293 Cells For AAV Manufacturing
To address scalability challenges of AAV manufacturing, we developed an HEK293 suspension cell line that can be used across many serotypes. Get the data in this article.
Operational and Financial Advantages of Cellicon® Cell Retention Solution in an N-1 Perfusion Process
This page describes the financial and operational advantages offered by the Cellicon® Cell Retention Device in an N-1 perfusion process at the 2,000 L scale in comparison to a cell retention device from another supplier.
Amplify Your Upstream Ecosystem
Eliminate the need to clean, autoclave and assemble your traditional glass bioreactors and save days of downtime with the Mobius® 3L Single-use Bioreactor.
Cell Retention Technology and Specialized Cell Culture Media for Intensified Upstream Processing
How the Cellicon® filter and controller enables seamless adoption of a perfused N-1 seed train step into the cell expansion process.
Direct upstream monitoring with Raman ready-to-use models
Streamline upstream process monitoring with embedded Raman ready-to-use models for easy implementation and improved process understanding
Glycosylation Modulation in Fed-batch Production of Therapeutic Proteins
Enhance mAb and recombinant protein performance, efficacy, and stability with precise glycosylation modulation using the Cellvento® ModiFeed platform.
Virus-like Particle (VLP) Vaccine Bioprocessing and Formulation Steps
This technical article breaks down the steps of upstream and downstream bioprocessing and formulation of virus-like particle vaccines.
Protein Fingerprinting of a Viral Vector, AAV5
Method development for protein fingerprinting of AAV serotype 5
using both intact mass analysis and peptide mapping, to determine critical quality attributes for gene therapy, utilizing three different columns.
DNA Detection
Nancy-520 for DNA Detection and Quantitation