Showing 1-14 of 14 results for "

144-48-9

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Jon Bondebjerg et al.
Chembiochem : a European journal of chemical biology, 4(2-3), 186-194 (2003-03-05)
A bicyclic thioether analogue of alpha-conotoxin G1, a neurotoxin found in the venom of cone snails, was synthesized on solid phase. Two successive intramolecular on-bead cyclizations between a cysteine residue and a chloroacetylated reduced peptide bond are the key steps...
Nagwan El-Habashi et al.
Veterinary pathology, 56(5), 691-702 (2019-01-29)
Encephalitis in hamsters, which was induced by equine herpesvirus (EHV)-9, EHV-1 strain Ab4p, and zebra-borne EHV-1, was investigated and compared to assess viral kinetics and identify the progression and severity of neuropathological findings. Hamsters were inoculated with EHV-9, EHV-1 strain...
Sara Marinelli et al.
BMC cancer, 14, 403-403 (2014-06-07)
Development of escape pathways from antiangiogenic treatments was reported to be associated with enhanced tumor aggressiveness and rebound effect was suggested after treatment stop. Aim of the study was to evaluate tumor response simulating different conditions of administration of antiangiogenic...
Diane M Longo et al.
Journal of translational medicine, 12, 178-178 (2014-06-24)
Single-cell network profiling (SCNP) is a multiparametric flow cytometry-based approach that simultaneously measures evoked signaling in multiple cell subsets. Previously, using the SCNP approach, age-associated immune signaling responses were identified in a cohort of 60 healthy donors. In the current...
O P Mgbonyebi et al.
Anticancer research, 18(2A), 751-755 (1998-06-06)
[2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylp urine] (roscovitine) is a potent and selective inhibitor of cyclin-dependent kinases cdc2 and cdk2. In this study, we evaluated the potential involvement of this novel cyclin-dependent kinase inhibitor in the proliferative activity of malignant and non-malignant human breast epithelial...
S N Savvides et al.
The Journal of biological chemistry, 271(14), 8101-8107 (1996-04-05)
We have determined the crystal structure of a complex between the noncompetitive inhibitor (Kis = 27 microM, Kii = 48 microM with respect to oxidized glutathione (GSSG) and Kis = 144 microM, Kii = 176 microM with respect to NADPH)...
Santosh Kumar Gupta et al.
Clinical nuclear medicine, 38(3), 188-194 (2013-02-16)
The aim of this work was to calculate the radiation absorbed dose to kidneys, liver, spleen, pituitary gland, and neuroendocrine tumors (NETs) of patients treated with (177)Lu-DOTATATE. We enrolled 61 patients (male/female patients, 40/21) with mean age of 48.1 ±...
Cristiana Angelucci et al.
International journal of oncology, 38(6), 1501-1509 (2011-04-12)
Reduced cell-cell adhesion allows malignant epithelial cells to invade the basal membrane and penetrate the stroma. This implies the potential of the cells to escape from the primary tumor as well as spreading ability. Herein, we investigated the effects of...
Gabriele Masi et al.
Neuropsychiatric disease and treatment, 14, 2287-2296 (2018-09-21)
Our aims were to explore the developmental trajectories of callous-unemotional (CU) traits using a growth curve analysis in Italian children with disruptive behavior disorders treated with a multimodal intervention, and to test both predictors and distal outcomes of CU traits...
H J Bovenschen et al.
The British journal of dermatology, 153(1), 72-78 (2005-07-21)
T-cell infiltration in plaque psoriasis has recently been an important subject of investigation. Interestingly, comparative analyses of the disease-specific composition of the lesional T-cell infiltrate in plaque psoriasis and other inflammatory dermatoses have only sparsely been performed. To compare plaque...
David Neal Franz et al.
The Lancet. Oncology, 15(13), 1513-1520 (2014-12-03)
In the EXIST-1 trial, initiated on Aug 10, 2009, more than 35% of patients with subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis complex had at least 50% reduction in SEGA volume after 9·6 months of treatment with everolimus....
Xiu-yu Liao et al.
Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 22(5), 282-284 (2010-06-04)
To investigate the protection mechanism of reduced glutathione (GSH) in acute lung injury in rats with sepsis. Sepsis in Sprague-Dawley (SD) rats were reproduced by cecal ligation and puncture (CLP). They were randomly divided into four groups, sham-operated group, model...
P de Lange et al.
Endocrinology, 142(8), 3414-3420 (2001-07-19)
Thyroid hormones increase energy expenditure, partly by reducing metabolic efficiency. The control of specific genes at the transcriptional level is thought to be the major molecular mechanism. However, both the number and the identity of the thyroid hormone-controlled genes remain...
John Greinwald et al.
The Laryngoscope, 123(6), 1537-1546 (2013-02-13)
To describe the clinical phenotype of pediatric patients with unilateral enlarged vestibular aqueduct (EVA) and then to compare the findings to two clinically related phenotypes: bilateral EVA and unilateral hearing loss without EVA. In view of clinical observations and previously...