Showing 1-14 of 14 results for "

148-82-3

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B Weber et al.
British journal of pharmacology, 133(8), 1243-1248 (2001-08-11)
1. Dopamine release in the retina is subject to modulation via autoreceptors, which belong to the D(2) receptor family (encompassing the D(2), D(3) and D(4) receptors). The aim of the present study was to determine the receptor subtype (D(2) vs...
R M Payne et al.
Biochimica et biophysica acta, 1089(3), 352-361 (1991-07-23)
Creatine kinase (CK; EC 2.7.3.2) isoenzymes play prominent roles in energy transduction. Mitochondrial CK (MtCK) reversibly catalyzes the transfer of high energy phosphate to creatine and exists, in the human, as two isoenzymes encoded by separate genes. We report here...
Meng-hong Sun et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 40(10), 655-659 (2012-02-11)
To retrospectively analyze epidermal growth factor receptor (EGFR) gene mutation frequencies and distribution characteristics in Chinese patients with non-small-cell lung carcinoma (NSCLC) by direct gene sequencing. Clinical samples from 443 NSCLC patients were obtained for EGFR gene mutation analysis, including...
Xi-peng Wang et al.
Zhonghua fu chan ke za zhi, 39(4), 238-241 (2004-05-08)
To investigate the association between the C677T and A1298C mutation of 5,10-methylenetetrahydrofolate reductase (MTHFR) gene and unexplained recurrent spontaneous abortion (URSA) in Chinese population. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to detect the mutation of C677T and...
Annette T Y Wong et al.
The Journal of clinical endocrinology and metabolism, 99(1), E122-E126 (2013-11-10)
The mechanisms responsible for impaired chylomicron metabolism have not been adequately investigated in obese subjects. We aimed to compare apolipoprotein (apo) B-48 kinetics in obese and lean men by developing a new model to describe the kinetics of apoB-48 particles...
R Abdi et al.
Transplantation, 72(4), 726-729 (2001-09-07)
Polymorphism of the genes associated with angiotensin, including angiotensin-converting enzyme (ACE), angiotensinogen (AGT), and the type 1 (AT1) and type 2 (AT2) angiotensin II receptors, has been implicated in the pathophysiology of hypertension, ischemic heart disease, and progression of chronic...
Chun-Fang Xu et al.
Journal of hepatology, 54(6), 1237-1243 (2010-12-15)
Pazopanib has demonstrated clinical benefit in patients with advanced renal cell carcinoma (RCC) and is generally well tolerated. However, transaminase elevations have commonly been observed. This 2-stage study sought to identify genetic determinants of alanine transaminase (ALT) elevations in pazopanib-treated...
Iwona Lugowska et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 36(11), 8277-8285 (2015-05-24)
The identification of prognostic factors in cutaneous melanoma allows choosing the most effective treatment, especially in group of patients with locoregional disease. Markers related to carcinogenesis and angiogenesis in particular have effect on the course of the disease. The aim...
Matthew J Kogut et al.
Journal of vascular and interventional radiology : JVIR, 24(3), 326-331 (2013-02-06)
To evaluate the impact of prophylactic use of dexamethasone and scopolamine on analgesic and antiemetic agent requirements after transarterial chemoembolization. A total of 148 patients underwent 316 rounds of chemoembolization for hepatocellular carcinoma at a single institution over a 17-month...
Takeyuki Suzuki et al.
The Biochemical journal, 411(3), 581-591 (2008-01-25)
ARMc8 (armadillo-repeat-containing protein 8) is a key component of the CTLH (C-terminal to lissencephaly type-1-like homology motif) complex in mammalian cells. This complex is well conserved in Saccharomyces cerevisiae and has been characterized as a FBPase (fructose-1, 6-bisphosphatase)-degrading complex. The...
R H Kim et al.
Matrix biology : journal of the International Society for Matrix Biology, 14(1), 31-40 (1994-01-01)
Bone sialoprotein (BSP) is a major structural protein of the bone matrix that is specifically expressed by fully-differentiated osteoblasts. To characterize the gene and to study the tissue-and differentiation stage-specific regulation of BSP gene transcription we have isolated and partially...
L Kooistra et al.
Clinical endocrinology, 73(5), 661-665 (2010-08-20)
To study the relationship between maternal thyrotrophin (TSH) and breech presentation at term. Combined data sets of two prospective studies to obtain adequate epidemiological power. One thousand and fifty-eight healthy pregnant women (58 breech, 1000 cephalic) and 131 women who...
Rebecca F McKnight et al.
Lancet (London, England), 379(9817), 721-728 (2012-01-24)
Lithium is a widely used and effective treatment for mood disorders. There has been concern about its safety but no adequate synthesis of the evidence for adverse effects. We aimed to undertake a clinically informative, systematic toxicity profile of lithium....
Yaling Han et al.
JAMA, 313(13), 1336-1346 (2015-03-17)
The safety and efficacy of bivalirudin compared with heparin with or without glycoprotein IIb/IIIa inhibitors in patients with acute myocardial infarction (AMI) undergoing primary percutaneous coronary intervention (PCI) are uncertain. To determine if bivalirudin is superior to heparin alone and...