Showing 1-29 of 29 results for "


Stina Syvänen et al.
BMC medical imaging, 7, 6-6 (2007-08-01)
The previously validated NK1-receptor ligand [O-methyl-11C]GR205171 binds with a high affinity to the NK1-receptor and displays a slow dissociation from the receptor. Hence, it cannot be used in vivo for detecting concentration changes in substance P, the endogenous ligand for...
Adam J Young et al.
Journal of inorganic biochemistry, 199, 110707-110707 (2019-08-02)
N-Heterocyclic carbene-stabilized metal nanoparticles have drawn much attention over the last decade due their strong carbon metal bond. Although several reports show increased stability of such N-heterocyclic carbene-stabilized metal nanoparticles, only limited examples of water-soluble N-heterocyclic carbene stabilized metal nanoparticles...
Vibrational analysis of 1-iodopropane, 1-iodobutane and 1, 3-diiodopropane.
Crowder GA and Ali S
Journal of Molecular Structure, 25(2), 377-386 (1975)
Joanna Kozłowska et al.
Molecules (Basel, Switzerland), 24(4) (2019-02-17)
In our investigation, we concentrated on naringenin (NG)-a widely studied flavanone that occurs in citrus fruits. As a result of a reaction with a range of alkyl iodides, 7 novel O-alkyl derivatives of naringenin (7a⁻11a, 13a, 17a) were obtained. Another...
Yi Ping Zheng et al.
Oncology letters, 15(4), 4087-4092 (2018-03-16)
microRNAs (miRs) are targets for genomic aberrations and emerging treatments against cancer. It has been demonstrated that targeting miR-569 may potentially benefit patients with ovarian or breast cancer. However, the exact roles of miR-569 remain unclear in human lung cancer...
Guang-Zhou Zhou et al.
Journal of biochemical and molecular toxicology, 29(6), 267-273 (2015-02-17)
The two important cell autonomic responses, autophagy, and apoptosis, play critical roles in cellular homeostasis and survival. By studying of the synthetic curcumin derivative hydrazinobenzoylcurcumin (HBC), we revealed that it could induce autophagy in nonsmall lung cancer cells (A549). Here...
Snehashis Choudhury et al.
Nature communications, 8(1), 898-898 (2017-10-14)
Secondary batteries based on earth-abundant sodium metal anodes are desirable for both stationary and portable electrical energy storage. Room-temperature sodium metal batteries are impractical today because morphological instability during recharge drives rough, dendritic electrodeposition. Chemical instability of liquid electrolytes also...
Jim Moselhy et al.
International journal of nanomedicine, 4, 153-164 (2009-09-24)
Thermoresponsive cationic nanogel (TCNG) networks based on N-isopropylacrylamide (NIPAM), 2-(dimethylamino)ethyl methacrylate (DMAEMA), and quaternary alkyl ammonium halide salts of DMAEMA (DMAEMAQ) were synthesized by dispersion polymerization technique. The thermoresponsive properties of TCNGs and TCNG-salmon sperm DNA (sasDNA) polyplexes were characterized...
N-alkylation of indole and pyrroles in dimethyl sulphoxide.
Heaney H and Ley SV
Journal of the Chemical Society. Perkin Transactions 1, 499-500 (1973)
Jiang Sheng et al.
Physical chemistry chemical physics : PCCP, 18(47), 32293-32301 (2016-11-17)
Monodisperse anatase hierarchical microspheres were produced via a simple sol-gel process. These microspheres in the sub-wavelength diameter of 320-750 nm could scatter visible light efficiently as whispering gallery modes (WGM) corresponding to the dye sensitized wavelength, and load a large...
Marco Kreidl et al.
Analytical methods : advancing methods and applications, 12(35), 4377-4386 (2020-08-28)
This study reports the synthesis of the room temperature ionic liquid 1-propyloxy-3-ethoxyimidazolium bis(trifluoromethane)sulfonamide for the extraction of bergapten and bergamottin from hydroalcoholic cosmetic samples by means of dispersive liquid-liquid microextraction. Molecular structures of the final ionic liquid as well as...
Xiaocun Yang et al.
Bioengineered, 8(1), 14-20 (2016-10-30)
The objective is to explore the effect of testosterone on the proliferation and collagen synthesis of neonatal rat cardiac fibroblasts (CF) induced by Angiotensin II (Ang II) and the underlying mechanisms. Derived from neonatal rats, the CFs were divided into...
Laura K G Youngster et al.
Applied microbiology and biotechnology, 80(6), 1113-1120 (2008-09-18)
Methyl tert-butyl ether (MTBE) contamination is widespread in aquifers near urban areas around the world. Since this synthetic fuel oxygenate is resistant to most physical methods of treating fuel-contaminated water, biodegradation may be a useful means of remediation. Currently, information...
Mi Young Jeon et al.
Nature, 543(7647), 690-694 (2017-03-16)
A zeolite with structure type MFI is an aluminosilicate or silicate material that has a three-dimensionally connected pore network, which enables molecular recognition in the size range 0.5-0.6 nm. These micropore dimensions are relevant for many valuable chemical intermediates, and therefore...
Joel E Schmidt et al.
Angewandte Chemie (International ed. in English), 53(32), 8372-8374 (2014-06-26)
Crystalline molecular sieves are used in numerous applications, where the properties exploited for each technology are the direct consequence of structural features. New materials are typically discovered by trial and error, and in many cases, organic structure-directing agents (OSDAs) are...
Miklós Nagy et al.
Molecules (Basel, Switzerland), 25(4) (2020-02-23)
: Multiple drug resistant fungi pose a serious threat to human health, therefore the development of completely new antimycotics is of paramount importance. The in vitro antifungal activity of the original, 1-amino-5-isocyanonaphthalenes (ICANs) was evaluated against reference strains of clinically...
Kelvine Chignen Possi et al.
Journal of medicinal chemistry, 60(22), 9263-9274 (2017-10-14)
Azapeptide analogues of growth hormone releasing peptide-6 (GHRP-6) exhibit promising affinity, selectivity, and modulator activity on the cluster of differentiation 36 receptor (CD36). For example, [A
Qun He et al.
Yi chuan = Hereditas, 26(3), 361-363 (2005-01-11)
Suggested a new blocking method for DNA microarray: 1-iodo-propane. We compared the difference between the two block reagents and the blocking results in different blocking time. The results showed that 1-I-propane is batter-blocking reagent than succinic anhydride in DNA chip....
Ping-Chia Li et al.
Journal of cellular physiology, 192(2), 188-199 (2002-07-13)
The effects of LY-171883, an orally active leukotriene antagonist, on membrane currents were examined in pituitary GH(3) and in neuroblastoma IMR-32 cells. In GH(3) cells, LY-171883 (1-300 microM) reversibly increased the amplitude of Ca(2+)-activated K(+) current in a concentration-dependent manner...
J P Patel et al.
Critical care medicine, 23(2), 231-237 (1995-02-01)
Both thromboxane A2 and peptide leukotrienes D4/E4 have been implicated in the pathophysiology of circulatory shock. In the present study, we evaluated the effect of thromboxane A2 and leukotriene D4/E4 receptor antagonism in circulatory shock. Prospective, randomized, controlled trial. Research...
S A Kliewer et al.
Proceedings of the National Academy of Sciences of the United States of America, 91(15), 7355-7359 (1994-07-19)
To gain insight into the function of peroxisome proliferator-activated receptor (PPAR) isoforms in mammals, we have cloned and characterized two PPAR alpha-related cDNAs (designated PPAR gamma and -delta, respectively) from mouse. The three PPAR isoforms display widely divergent patterns of...
K Hisamatsu et al.
Prostaglandins, 51(1), 69-79 (1996-01-01)
To clarify the effects of leukotriene C4 (LTC4) on human ciliated epithelium, ciliary activity of the ethmoid sinus mucosa was measured photoelectrically in tissue culture. At concentrations ranging from 10(-6)M to 10(-9)M, LTC4 showed minimal effects on the ciliated epithelium...
T Tanaka et al.
Forensic science international, 71(1), 57-64 (1995-01-21)
We studied the effects of a selective antagonist of peptide leukotriene D4/E4 (LY-171883) and 5-lipoxygenase inhibitor diethylcarbamazine (DEC) in renal failure induced by a tourniquet, because peptide leukotrienes (LTs) were suggested to play a key role in our previous study....
B Boris Vargaftig et al.
American journal of physiology. Lung cellular and molecular physiology, 285(4), L808-L818 (2003-06-10)
Antigen induces murine bronchial hyperreactivity (BHR), inflammation, mucus accumulation, and airway remodeling. To investigate whether leukotrienes (LT) mediate the effects of antigen [ovalbumin (Ova)], we studied 5-lipoxygenase (5-LO) expression in immunized BP2 mice and blocked LT synthesis with the 5-LO...
N J Gross et al.
Radiation research, 127(3), 317-324 (1991-09-01)
Corticosteroids have previously been found to be protective against the mortality of radiation pneumonitis in mice, even when given well after lethal lung irradiation. We explored the possibility that this effect was due to their well-known anti-inflammatory actions by giving...
Raquel Grau et al.
The Biochemical journal, 395(1), 81-88 (2005-12-14)
Recent evidence indicates that PPAR (peroxisome-proliferator-activated receptor) alpha ligands possess anti-inflammatory and antitumoural properties owing to their inhibitory effects on the expression of genes that are involved in the inflammatory response. However, the precise molecular mechanisms underlying these effects are...
G Chen et al.
International archives of allergy and immunology, 116(2), 132-139 (1998-07-04)
Airway hyperreactivity is a hallmark of asthma. Yet, the role of allergic sensitization in the hyperreactivity remains controversial. This study examined the effects of airborne cockroach allergen (CRa) sensitization on the contractility of bronchial (BSM) and tracheal (TSM) smooth muscle...
Sumei Liu et al.
European journal of pharmacology, 459(1), 27-39 (2002-12-31)
Conventional intracellular microelectrodes, neuronal tracer injection techniques and immunohistochemistry were used to study the actions of cysteinyl leukotrienes (CysLTs) on electrical and synaptic behavior of enteric neurons in guinea-pig stomach and small intestine. Bath application of leukotriene C(4), leukotriene D(4)...
T S Rao et al.
The Journal of pharmacology and experimental therapeutics, 269(3), 917-925 (1994-06-01)
Intraperitoneal administration of zymosan to mice resulted in marked biosynthesis of eicosanoids and influx of neutrophils with distinct time course profiles. 6-Keto-prostaglandin-F1 alpha (6-KPA) increased between 30 and 60 min and rapidly decreased thereafter. Leukotriene (LT)C4 levels showed similar patterns...