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Showing 1-15 of 15 results for "190284" within Papers
G E Bast et al.
Archives of toxicology, 71(3), 179-186 (1997-01-01)
Isolated rabbit ears were single-pass perfused with a protein-free medium. Permethrin (0.05-23.5%, w/w) was applied in four distinct ointments. Permethrin, 3-phenoxybenzyl alcohol, 3-phenoxybenzaldehyde, and 3-phenoxybenzoic acid were analysed by HPLC. Permethrin was not detected in the effluent. The permeation coefficient
Sh T Iskandarova
Gigiena i sanitariia, (6)(6), 6-8 (1995-11-01)
The threshold level of 3-phenoxybenzyl alcohol (3-PBA) in ambient air was set up at 0.48 mg/m3. Inhalation of 3-PBA in concentrations of 4.86 and 0.518 mg/m3 caused changes in the central nervous system, metabolic processes, liver function, reduced the nonspecific
Brian Laffin et al.
Toxicology, 267(1-3), 39-44 (2009-10-27)
Synthetic pyrethroids are one of the most frequently and widely used class of insecticides, primarily because they have a higher insect to mammalian toxicity ratio than organochlorines or organophosphates. The basic structure of pyrethroids can be characterized as an acid
G E Bast et al.
Skin pharmacology and applied skin physiology, 11(4-5), 250-257 (1999-01-14)
The formation of 3-phenoxybenzoic acid from 3-phenoxybenzyl alcohol was determined in (a) rabbit ears, single-pass perfused with a protein-free buffer, pH 7.4; (b) the microsomal fraction and its supernatant from homogenized rabbit skin; and (c) purified alcohol dehydrogenase from horse
Yuri Nakamura et al.
Toxicology, 235(3), 176-184 (2007-04-25)
The in vitro metabolism of permethrin and its hydrolysis products in rats was investigated. Cis- and trans-permethrin were mainly hydrolyzed by liver microsomes, and also by small-intestinal microsomes of rats. trans-Permethrin was much more effectively hydrolyzed than the cis-isomer. When
Hee-Joo Kim et al.
Journal of agricultural and food chemistry, 55(10), 3750-3757 (2007-04-26)
Pyrethroids are widely used in agriculture as insecticides. This study describes a sensitive enzyme-linked immunosorbent assay for the detection of the glucuronide conjugate of 3-phenoxybenzyl alcohol, a putative pyrethroid metabolite that may be used as a biomarker of exposure to
Dhivya Vadhana et al.
Cardiovascular toxicology, 11(3), 226-234 (2011-05-21)
Due to increased global use, acute and chronic exposures to pyrethroid insecticides in humans are of clinical concern. Pyrethroids have a primary mode of action that involves interference with the sodium and calcium channels in excitable cells, which may include
Nongkran Lumjuan et al.
PloS one, 9(7), e102746-e102746 (2014-07-23)
Pyrethroid insecticides, especially permethrin and deltamethrin, have been used extensively worldwide for mosquito control. However, insecticide resistance can spread through a population very rapidly under strong selection pressure from insecticide use. The upregulation of aldehyde dehydrogenase (ALDH) has been reported
[Gas chromatographic determination of butyl alcohols in the atmospheric air].
V A Ushakova et al.
Gigiena i sanitariia, (2)(2), 68-69 (1990-02-01)
Tomoyuki Takaku et al.
Journal of agricultural and food chemistry, 59(9), 5001-5005 (2011-04-05)
To estimate the metabolic profile of trans-permethrin in humans, a comparison of the in vitro metabolism of trans-permethrin in humans and rats was conducted using hepatic microsomes, and cytochrome P450 and UDP-glucuronyltransferase isoforms, which catalyze the metabolism of 3-phenoxybenzyl alcohol
Naoko Hirosawa et al.
Toxicology letters, 203(1), 28-32 (2011-03-08)
Pyrethroid insecticide (PYR) is used worldwide in agriculture and for indoor extermination of harmful insects. Urinary PYR metabolites (e.g. 3-phenoxybenzoic acid, 3PBA) have been used as the most sensitive biomarker for environmental PYR exposure since the late 1990s. In this
Ramon Lavado et al.
Toxicology letters, 226(2), 192-197 (2014-02-20)
Permethrin (PM) is a pyrethroid insecticide that exists as 4 enantiomers. Biotransformation of PM to estrogen receptor agonists (3-phenoxybenzyl alcohol (PBOH) and 3-(4'-hydroxyphenoxy)-benzyl alcohol (3,4 PBOH)) has been shown to be stereoselective in other vertebrate species. This study evaluated the
N Kaushik et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 36(3), 289-300 (2001-06-20)
The metabolism of fluvalinate in chickpea plants in the field under sub-tropical climatic conditions has been investigated. Ten days after spraying with fluvalinate, leaves were collected and extracted in acetone. The extract was fractionated and the metabolites were identified by
Development of a class selective immunoassay for the type II pyrethroid insecticides.
Mak SK, et al.
Analytica Chimica Acta, 534(1), 109-120 (2005)
J Allen Crow et al.
Toxicology and applied pharmacology, 221(1), 1-12 (2007-04-20)
Hydrolytic metabolism of pyrethroid insecticides in humans is one of the major catabolic pathways that clear these compounds from the body. Rodent models are often used to determine the disposition and clearance rates of these esterified compounds. In this study
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