Showing 1-30 of 1090 results for "

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Open channel noise. V. Fluctuating barriers to ion entry in gramicidin A channels.
S H Heinemann,F J Sigworth
Biophysical Journal null
K J Lee et al.
Electrophoresis, 15(1), 98-102 (1994-01-01)
The factors affecting micellar electrokinetic capillary chromatographic separation of hippuric and o-, m-, p-methylhippuric acid were investigated by changing the species of micelles, and adding urea to the micellar solution. The analysis of hippurates in human urine is demonstrated under...
Determination of levamisole and thiabendazole in meat by HPLC and photodiode array detection.
B Wyhowski de Bukanski,J M Degroodt,H Beernaert
Zeitschrift fur Lebensmittel-Untersuchung Und -Forschung null
Purification and biochemical characterization of a putative [6Fe-6S] prismane-cluster-containing protein from Desulfovibrio vulgaris (Hildenborough).
A J Pierik,R B Wolbert,P H Mutsaers,W R Hagen,C Veeger
European Journal of Biochemistry null
The amino acid sequence of rabbit J chain in secretory immunoglobulin A.
G J Hughes,S Frutiger,N Paquet,J C Jaton
The Biochemical Journal null
Effect of a salmon diet on the distribution of plasma lipoproteins and apolipoproteins in normolipidemic adult men.
F T Lindgren,G L Adamson,V G Shore,G J Nelson,P C Schmidt
Lipids null
Li Zhou et al.
Hepato-gastroenterology, 59(115), 840-843 (2012-04-04)
The significance of preoperative serum a-fetoprotein (AFP) level in hepatocellular carcinoma (HCC) treated with different modalities remains controversial. Besides, many cut-off values have been used. The present study aims to clarify significance of two major ones in HCC with cirrhosis....
Scott M Wheatley et al.
American journal of physiology. Endocrinology and metabolism, 306(1), E91-E99 (2013-11-07)
Many low-birth-weight infants experience failure to thrive. The amino acid leucine stimulates protein synthesis in skeletal muscle of the neonate, but less is known about the effects of the leucine metabolite β-hydroxy-β-methylbutyrate (HMB). To determine the effects of HMB on...
J Semba et al.
European journal of pharmacology, 230(3), 321-326 (1993-01-19)
The temporal inter-relationship of various amino acids and monoamine metabolites in rat cerebrospinal fluid was examined after acute administration of milacemide (100, 200 or 400 mg/kg i.p.), a glycine prodrug. Glycine concentrations rose linearly and dose dependently (20-190%) but were...
Florian Alten et al.
Documenta ophthalmologica. Advances in ophthalmology, 129(3), 203-207 (2014-10-03)
To evaluate structural and functional outcomes of intravitreal dexamethasone implant (IDI) in three patients presenting with nonarteritic anterior ischaemic optic neuropathy. IDI was administered once in three patients. Best-corrected visual acuity (BCVA), perimetry, volume spectral-domain optical coherence tomography scan of...
Ophelia Q P Yin et al.
Cancer chemotherapy and pharmacology, 71(1), 219-226 (2012-10-17)
This study evaluated the effects of either famotidine or antacid on the pharmacokinetics of nilotinib in healthy subjects, with the specific focus to explore different dosing separation schemes leading to a minimized drug-drug interaction. Fifty-two subjects were randomized to receive...
Gioconda Millotti et al.
Journal of pharmaceutical sciences, 103(10), 3165-3170 (2014-08-21)
Chitosan-6-mercaptonicotinic acid (chitosan-6-MNA) is a thiolated chitosan with strong mucoadhesive properties and a pH-independent reactivity. This study aimed to evaluate the in vivo potential for the oral delivery of insulin. The comparison of the nonconjugated chitosan and chitosan-6-MNA was performed...
J M Benson et al.
Research report (Health Effects Institute), (102)(102), 73-94 (2001-08-16)
The purpose of these studies was to extend previous evaluation of methyl tert-butyl ether (MTBE)* tissue distribution, metabolism, and excretion in rats to include concentrations more relevant to human exposure (4 and 40 ppm) and to determine the effects of...
Harold M J F van der Heijden et al.
Tijdschrift voor diergeneeskunde, 136(6), 410-416 (2011-06-28)
Histomonosis, a parasitic disease of galliformes and sporadically of other birds caused by Histomonas meleagridis, can result in very high mortality, especially in turkeys. The ban on the last antihistomonal drug prompted an urgent search for alternative prevention and treatment...
Virginia Norris et al.
Pulmonary pharmacology & therapeutics, 26(5), 574-580 (2013-03-26)
There are few data on the bronchodilatory effects of adding short-acting bronchodilators (SABA) to maintenance, long-acting bronchodilator therapy. This study assessed the additional bronchodilation and safety of adding supratherapeutic doses of salbutamol (SALB) or ipratropium bromide (IPR) to the novel...
Hossein Ayatollahi et al.
Phytotherapy research : PTR, 28(4), 539-543 (2013-06-05)
Saffron showed some effects on blood coagulation and platelet aggregation in in vitro and in vivo studies. In a clinical trial with a limited number volunteers, saffron tablets influenced on bleeding time. In this study, the effect of saffron on...
Thiago Caon et al.
Journal of pharmaceutical sciences, 103(6), 1643-1651 (2014-04-02)
The potential of the buccal mucosa as an alternative route for the systemic delivery of donepezil (DPZ) hydrochloride, and the impact of various skin penetration enhancers on DPZ buccal permeability, was assessed using an in vitro model. DPZ was applied...
Amirah Al-Attas et al.
Biomedical chromatography : BMC, 29(12), 1811-1818 (2015-06-11)
A green, novel, rapid, accurate and reliable capillary zone electrophoresis method was developed and validated for the simultaneous determination of piperacillin, tazobactam and cefepime in pharmaceutical preparations. Separation was carried out using fused silica capillary (50 µm i.d. × 48.6 cm and 40.2 cm detection...
Magdalena Alonso-Galicia et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 283(1), R60-R68 (2002-06-19)
The present study examined the effects of ANG II on the renal synthesis of 20-hydroxyeicosatetraenoic acid (20-HETE) and its contribution to the renal vasoconstrictor and the acute and chronic pressor effects of ANG II in rats. ANG II (10(-11) to...
Manee Luangtana-anan et al.
Journal of agricultural and food chemistry, 58(24), 12934-12940 (2010-11-26)
The effects of molecular weight and concentration of plasticizer on physicochemical properties and stability of shellac films were investigated. Type of plasticizer was previously reported to have some effects on the stability of shellac films, and polyethylene glycol (PEG) was...
Yanfeng Wang et al.
British journal of clinical pharmacology, 65(6), 885-892 (2008-04-04)
Imatinib, a tyrosine kinase inhibitor, exhibits a competitive inhibition on the CYP450 2D6 isozyme with a K(i) value of 7.5 microm. However, the clinical significance of the inhibition and its relevance to 2D6 polymorphisms have not been evaluated. The pharmacokinetics...
J D Medh et al.
The Journal of biological chemistry, 270(2), 536-540 (1995-01-13)
The 39-kDa receptor-associated protein (RAP) is cosynthesized and co-purifies with the low density lipoprotein receptor-related protein (LRP)/alpha 2-macroglobulin receptor and is thought to modulate ligand binding to LRP. In addition to binding LRP, RAP binds two other members of the...
Paola Palumbo et al.
Journal of cellular physiology, 230(8), 1974-1981 (2015-03-05)
Nowadays, fat tissue transplantation is widely used in regenerative and reconstructive surgery. However, a shared method of lipoaspirate handling for ensuring a good quality fat transplant has not yet been established. The study was to identify a method to recover...
Kim G Jackson et al.
Nutrition, metabolism, and cardiovascular diseases : NMCD, 16(6), 405-417 (2006-08-29)
We examined the effect of meal fatty acids on lipid and apolipoprotein concentrations of very low density lipoprotein (VLDL) and chylomicron/chylomicron remnants in lipid fractions with a Svedberg flotation rate (Sf) 60-400 and Sf 20-60. Six healthy middle-aged men received...
R I Freudenthal et al.
International journal of toxicology, 20(5), 269-274 (2002-01-05)
Phosflex 51B is a flame retardant plasticizer that is blended with polyvinyl chloride films to effectively control product flammability. Its composition places it in the butylated triphenyl phosphate category. Previous studies have shown Phosflex 51B to have low acute toxicity...
Craig Robertson et al.
Journal of strength and conditioning research, 34(3), 828-837 (2018-06-26)
Robertson, C, Lodin-Sundström, A, O'Hara, J, King, R, Wainwright, B, and Barlow, M. Effects of pre-race apneas on 400-m freestyle swimming performance. J Strength Cond Res 34(3): 828-837, 2020-This study aimed to establish whether a series of 3 apneas before...
Cameron C Grant et al.
Pediatrics, 133(1), e143-e153 (2013-12-18)
To determine the vitamin D dose necessary to achieve serum 25-hydroxyvitamin D (25(OH)D) concentration ≥ 20 ng/mL during infancy. A randomized, double-blind, placebo-controlled trial in New Zealand. Pregnant mothers, from 27 weeks' gestation to birth, and then their infants, from...
Noemi Lupo et al.
International journal of pharmaceutics, 526(1-2), 23-30 (2017-04-27)
Evaluation of inhibitory effect of emulsifiers on pancreatic trypsin and α-chymotrypsin. The inhibitory effect of Cremophor EL, Cremophor RH 40, Brij O10, Tween 20, polyethylene glycol 8000, polyethylene glycol 400, Carbitol, Pemulen TR-1, Pemulen TR-2, Carbopol Ultrez 20 and Carbopol...
P Angeli et al.
Gut, 59(1), 98-104 (2009-07-03)
The aim of the study was to compare sequential versus combined diuretic therapy in patients with cirrhosis, moderate ascites and without renal failure. One hundred patients were randomly assigned to the two diuretic treatments. The sequential treatment provided potassium canrenoate...
David Banji et al.
Indian journal of experimental biology, 52(2), 153-158 (2014-03-07)
Administration of aqueous extract of T. aestivum (200 and 400 mg/kg/day, po, for 30 days) and risedronate (20 microg/kg, sc, five times a week for 30 days) following methyl prednisolone sodium succinate (10 mg/kg, sc, thrice a week for 4...