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J A Carew et al.
Journal of thrombosis and haemostasis : JTH, 1(6), 1220-1227 (2003-07-23)
Factor (F)VII plays a critical role in initiation of coagulation. Several segments within the 5' flanking region of the FVII gene were previously demonstrated to recognize hepatic nuclear proteins, but few have been identified. To identify a regulatory protein binding
Oliver A Cornely et al.
The Journal of antimicrobial chemotherapy, 72(12), 3406-3413 (2017-09-30)
A two-part (Phase 1B/3), sequential, open-label, multicentre study evaluated the pharmacokinetics (PK) and safety of intravenous (iv) posaconazole given as antifungal prophylaxis to neutropenic patients with AML or myelodysplastic syndrome (MDS) or to recipients at risk of invasive fungal disease
Hao Wu et al.
The Journal of allergy and clinical immunology, 125(2), 321-327 (2009-11-17)
More than 200 asthma candidate genes have been examined in human association studies or identified with knockout mouse approaches. However, many have not been systematically replicated in human populations, especially those containing a large number of tagging single nucleotide polymorphisms
Singh Pooja et al.
Breast cancer research and treatment, 126(3), 739-747 (2010-09-30)
TNF-α and -β, the multi-functional pro-inflammatory cytokines, are known to play important roles in both tumor progression and destruction based on their concentrations. Growth factors and various stimuli such as cytokines regulate proliferation of the breast epithelial cells. Therefore, the
D Adelmann et al.
British journal of anaesthesia, 113(4), 628-633 (2014-05-30)
Postoperative haemorrhage in neurosurgery is associated with significant morbidity and mortality. There is controversy whether or not factor XIII (FXIII) deficiency leads to bleeding complications after craniotomy. Decreased fibrinogen levels have been associated with an increased incidence of bleeding complications
Maneesh Arya et al.
Biophysical journal, 88(6), 4391-4401 (2005-03-15)
The first stage in hemostasis is the binding of the platelet membrane receptor glycoprotein (GP) Ib-IX complex to the A1 domain of von Willebrand factor in the subendothelium. A bleeding disorder associated with this interaction is platelet-type von Willebrand disease
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