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Sol-Gel Science for Ceramic Materials
Research involving reactive silicone chemistry has focused on the production of pure silicon and hybrid materials, hydrosilylation, ring-opening and atom transfer polymerizations, polymerizations with controlled stereochemistry, and condensation reactions.
Dynamic Live Cell Imaging of Caspase Mediated Apoptosis and Cellular Hypoxia in Lymphocytes and Cancer Cells Using the CellASIC® ONIX2 Microfluidic Platform
Application note on how the CellASIC® ONIX2 microfluidic system can be used to analyze caspase-3 mediated apoptosis/cell death and cellular hypoxia in live immune and cancer cell lines.
Privileged structures are a class of molecules that are capable of binding to multiple receptors with high affinity. In order to be considered privileged, a substructure should represent a molecule’s core element and make up a significant portion of its...
Stable Isotopes
ISOTEC® Stable Isotopes are stable isotope compounds, ranging from gases to complex molecules, that are useful for tracer studies in proteomics and metabolomics, agents for MRI / MRS, and in a wide range of other biomedical applications.
Iron Oxide Nanoparticles, Characteristics and Applications
Iron oxide (IO) nanoparticles consist of maghemite (γ-Fe2O3) and/or magnetite (Fe3O4) particles with diameters ranging from 1 and 100 nanometer and find applications in magnetic data storage, biosensing, drug-delivery etc.
Use of PEPscreen® Libraries to Identify CD8 Epitopes Presented During Malaria Infection
Malaria caused by Plasmodium species kills more than one million people per year, 90% of them in sub-Saharan Africa. Our previous work had shown that CD8 T cells are a major component of immunity to the first stage of infection...
Protein Determination Modified Lowry Method
To standardize a procedure for the determination of protein by modified Lowry.
Restriction Endonucleases - The Molecular Scissors
The term “Restriction enzyme” originated from the studies of Enterobacteria phage λ (lambda phage) in the laboratories of Werner Arber and Matthew Meselson.
Determination of PAHs in Paprika Powder Using a Novel SPE Cartridge
Paprika is a spice made from dried sweet peppers, and is used for flavor and color in many types of cuisine. Contamination with polynuclear aromatic hydrocarbons (PAHs) can occur when pepper plants are exposed to these pollutants in the environment...
HPLC Columns & Accessories
Our wide selection of HPLC columns for small and large molecule analysis allows you to enhance the separation process in terms of retention, resolution, selectivity, and analysis time, all while reducing the time for method development.
Custom siRNA Libraries & Panels
MISSION siRNA Libraries offer the most compelling siRNA collections for high-throughput screening by targeting genes of high therapeutic value as defined with input from major pharmaceutical companies.
Folic Acid and Tetrahydrofolates in Cell Culture
Importance and uses of folic acid in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures. Folic acid and its reduced derivative(s), such as folinic acid, are an essential water soluble vitamins added to virtually all cell culture...
Phosphate in Groundwater and Surface Water: A Rapid and Reliable Determination Method using the Photometric Spectroquant® Test
The analysis of low concentrations of PO4-P in natural, uncontaminated waters is often challenging. The Spectroquant® photometric test provides an easy-to-use and sensitive method for quantification with results comparable to DIN EN ISO 6878.
Coupling Reagents
In principle, the seemingly simple formation of a peptide bond can be accomplished using all the procedures available in organic chemistry for the synthesis of carboxylic acid amides. However, due to the presence of various functional groups in natural and...
Applications of Organic Single-Crystalline Semiconductors
Recent developments in the applications of organic single-crystal semiconductors which allow their use in organic electronics and energy harvesting.
Glutamate/GABA Synthesis and Metabolism
Glutamine is a common precursor for the biosynthesis of both glutamate and GABA. Glutamine can be transported in and out of neurons and astrocytes utilizing different glutamine carriers. The neurotransmitter glutamate can be synthesized from glutamine by the action of...
Fluorescent Labeling of Peptides
Fluorescent Labeling of Peptides
Custom DNA and RNA Oligos & qPCR Probes Product Resources
Find all our product resources for our custom DNA and RNA oligos & qPCR probes products in a single place.
OligoArchitect™ Assay Design
Efficient qPCR relies on good assay design. Since the invention of PCR, many parameters have been identified as important for assay quality, such as estimates of oligo temperature characteristics, GC content and folding properties.
Custom siRNA Libraries & Panels Request Form
Please fill out the form to receive a price and delivery quotation.
Authenticated Breast Cancer Cell Lines for Cancer Research
Choose from more than 30 breast cancer cell lines authenticated by ECACC, classified by hormone receptor-positive, HER2-positive, and triple-negative cancers, as well as by known mutations such as BRCA2.
Authenticated Colorectal Cancer Cell Lines for Cancer Research
We offer mouse, rat, and 40+ human colorectal cancer cell lines including Caco-2 and HT29 for applications including drug delivery and treatment strategies, and metastasis studies. Choose cells with relevant mutations in genes such as KRAS, APC, TP53, and...
Single-Walled Carbon Nanotubes synthesized by the Super-Growth Method: Properties & Applications
Single-Walled Carbon Nanotubes synthesized by the Super-Growth Method & their properties & applications, including dispersing SGCNTs, SGCNT-polymer composites & SGCNT-metal composites are discussed.
Somatostatin Receptors
Sigma-Aldrich offers many products related to somatostatin receptors for your research needs.
Solid-State Metathesis Materials Synthesis
In the last two decades, a new method termed solid-state metathesis (SSM) has been developed to synthesize compounds that are often difficult to produce conventionally.
Probiotics in the Food Industry
Probiotics are defined as live bacteria with beneficial effects to the health of the host organism. Pimarily lactic acid bacteria (LAB) and bifidobacteria are used as probiotics, however certain yeasts and bacilli are also known to have positive effects
Fullerenes for Bioscience & Photovoltaic Applications
Find various photovoltaic and bioscience-based applications of fullerenes.
Cholecystokinin and Gastrin Receptors
The naturally occurring peptides, cholecystokinin (CCK) and gastrin closely resemble each other at their carboxyl terminus, which is the biologically active portion of the molecules.
G Proteins (Heterotrimeric)
Heterotrimeric G proteins, comprising α, β and γ subunits, respond to extracellular signals generated by activated seven-transmembrane (7TM) receptors by modulating intracellular effector proteins such as enzymes and ion channels.
Electrochemistry on the Bench and in the Field
Nanomaterials, electrochemistry, BASi, LIB, Lithium Ion Batteries, reference electrode, Teflon, silver nitrate, working electrodes, counter electrode, organic electrosynthesis
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