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Vanessa Cardoso Pires et al.
The British journal of nutrition, 110(11), 2020-2029 (2013-05-10)
The aim of the present study was to investigate the effects of long-term grape juice concentrate (GJC) consumption, in two dosages, on the reproductive parameters of cadmium-exposed male rats. The effects of the concentrate on body mass gain, plasma testosterone
Jill E Kucab et al.
Cell, 177(4), 821-836 (2019-04-16)
Whole-genome-sequencing (WGS) of human tumors has revealed distinct mutation patterns that hint at the causative origins of cancer. We examined mutational signatures in 324 WGS human-induced pluripotent stem cells exposed to 79 known or suspected environmental carcinogens. Forty-one yielded characteristic
Siqi Jia et al.
Journal of biochemical and molecular toxicology, 34(4), e22448-e22448 (2020-01-23)
This study aimed to investigate the protective effect of quercetin against the toxicity induced by chronic exposure to low levels of cadmium in rats by an ultra performance liquid chromatography mass spectrometer. Rats were randomly divided into six groups as
Sangwoo Lee et al.
Environmental monitoring and assessment, 187(7), 447-447 (2015-06-21)
Zacco platypus, pale chub, is an indigenous freshwater fish of East Asia including Korea and has many useful characteristics as indicator species for water pollution. While utility of Z. platypus as an experimental species has been recognized, genetic-level information is
Jelena Djokic et al.
Journal of immunotoxicology, 12(2), 115-123 (2014-05-16)
Although numerous investigations have demonstrated a direct effect of cadmium (Cd) on peripheral blood mononuclear cell (PBMC) activity in humans, there is virtually no data concerning the in vivo impact of this metal on circulatory mononuclear cells. In this study
Mohamed El-Boshy et al.
Journal of biochemical and molecular toxicology, 34(3), e22440-e22440 (2020-01-12)
Although vitamin D (VD) and calcium (Ca) attenuate cadmium (Cd) metabolism, their combined antioxidant and anti-inflammatory actions against Cd toxicity have not been previously explored. Hence, this study measured the protective effects of VD ± Ca supplements against Cd hepatotoxicity. Forty adult
Vikram Kapoor et al.
Environmental science & technology, 49(22), 13454-13462 (2015-10-27)
Heavy metals can inhibit nitrification, a key process for nitrogen removal in wastewater treatment. The transcriptional responses of amoA, hao, nirK, and norB were measured in conjunction with specific oxygen uptake rate (sOUR) for nitrifying enrichment cultures exposed to different
Anushruti Ashok et al.
Toxicological sciences : an official journal of the Society of Toxicology, 143(1), 64-80 (2014-10-08)
Environmental pollutants act as risk factors for Alzheimer's disease (AD), mainly affecting the aging population. We investigated early manifestations of AD-like pathology by a mixture of arsenic (As), cadmium (Cd), and lead (Pb), reported to impair neurodevelopment. We treated rats
Fouzia Amamou et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 78, 177-184 (2015-01-27)
Cadmium (Cd) is one of the most common heavy metal pollutants. It is accumulated particularly in liver and kidney. The present study examined the possible protective effect of olive oil and colocynth oil consumption against Cd-induced damage on plasma lipids
S Garcia-Santos et al.
Bulletin of environmental contamination and toxicology, 90(1), 55-59 (2012-11-28)
The cadmium impact on interrenal and thyroid functions was assessed in tilapia, Oreochromis niloticus. Fish were exposed to 25 mg L(-1) of CdCl(2) during 24, 48, and 96 h. Exposure to 24 and 48 h induced a significant increase in plasma cortisol levels
Sotirios Christodoulou et al.
Nature communications, 6, 7905-7905 (2015-07-30)
Strain in colloidal heteronanocrystals with non-centrosymmetric lattices presents a unique opportunity for controlling optoelectronic properties and adds a new degree of freedom to existing wavefunction engineering and doping paradigms. We synthesized wurtzite CdSe nanorods embedded in a thick CdS shell
A Kheradmand et al.
Andrologia, 47(6), 634-643 (2014-07-26)
Numerous reports demonstrate that cadmium (Cd) induces oxidative stress by increasing lipid peroxidation and altering antioxidative enzymes status. Thirty male rats were subdivided into control-saline, Cd-saline and Cd-ghrelin groups. A single dose of Cd was injected to induce testicular injury
Xiaohua Gao et al.
Environmental health perspectives, 123(4), 331-336 (2014-10-25)
It has been proposed that cadmium (Cd) is an environmental "metalloestrogen" and that its action is mediated via the estrogen receptor (ER). Cd mimics the effects of estrogen in the rat uterus, and blood Cd concentrations positively correlate with ER
M Martínez-Pacheco et al.
Gene, 533(2), 508-514 (2013-10-02)
Metals are a threat to human health by increasing disease risk. Experimental data have linked altered miRNA expression with exposure to some metals. MiRNAs comprise a large family of non-coding single-stranded molecules that primarily function to negatively regulate gene expression
Ulrike Klenke et al.
Endocrinology, 155(5), 1851-1863 (2014-02-26)
Metabolic dysfunctions are often linked to reproductive abnormalities. Adiponectin (ADP), a peripheral hormone secreted by white adipose tissue, is important in energy homeostasis and appetite regulation. GnRH neurons are integral components of the reproductive axis, controlling synthesis, and release of
Yingwei Li et al.
ACS nano, 14(6), 6599-6606 (2020-04-15)
Dipole moment (μ) is a critical parameter for molecules and nanomaterials as it affects many properties. In metal-thiolate (SR) nanoclusters (NCs), μ is commonly low (0-5 D) compared to quantum dots. Herein, we report a doping strategy to give giant
Patrícia Anacleto et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 104, 95-108 (2017-02-06)
The presence of contaminants in aquatic ecosystems can cause serious problems to the environment and marine organisms. This study aims to evaluate the phycoremediation capacity of macroalgae Laminaria digitata for pesticides (diflubenzuron and lindane) and toxic elements (cadmium and copper)
Adrian Türkcan et al.
Toxicological sciences : an official journal of the Society of Toxicology, 145(2), 360-371 (2015-03-15)
The deleterious effects of increased cadmium (Cd) serum levels on the cardiovascular system are proven by epidemiological and basic science studies. Cd exposure of animals and humans is known to impair myocardial function, possibly leading to heart failure. This study
Deng Pan et al.
Journal of AOAC International, 98(5), 1260-1266 (2015-11-04)
Cyclic voltammetry and differential pulse voltammetry were used to investigate the electrochemical behavior of uric acid (UA) at a CdTe quantum dot (QD) modified the glassy carbon electrode (GCE). CdTe QDs, as new semiconductor nanocrystals, can greatly improve the peak
Veronique E Miron et al.
Nature neuroscience, 16(9), 1211-1218 (2013-07-23)
The lack of therapies for progressive multiple sclerosis highlights the need to understand the regenerative process of remyelination that can follow CNS demyelination. This involves an innate immune response consisting of microglia and macrophages, which can be polarized to distinct
Tomasz Olszowski et al.
International journal of molecular sciences, 16(9), 21410-21427 (2015-09-16)
Cadmium at environmental concentrations is a risk factor for many diseases, including cardiovascular and neurodegenerative diseases, in which macrophages play an important role. The aim of this study was to evaluate the effects of cadmium at low environmental (nanomolar) concentrations
Sreoshi Chatterjee et al.
PloS one, 10(7), e0132697-e0132697 (2015-07-15)
Feeding cadmium chloride (50 or 1000 ppm CdCl2 in drinking water, ad libitum) to C57BL/6 mice resulted in a significant and sustained fall in blood erythrocyte count and hemoglobin levels that started 4 and 3 weeks after the start of
Mélanie Aye et al.
Mutation research, 750(1-2), 129-138 (2012-11-14)
We proposed to evaluate the genotoxicity and mutagenicity of a new quantum dots (QDs) nanoplatform (QDsN), consisting of CdSe/ZnS core-shell QDs encapsulated by a natural fusogenic lipid (1,2-di-oleoyl-sn-glycero-3-phosphocholine (DOPC)) and functionalized by a nucleolipid N-[5'-(2',3'-di-oleoyl) uridine]-N',N',N'-trimethylammoniumtosylate (DOTAU). This QDs nanoplatform
Sumana Das et al.
General and comparative endocrinology, 181, 107-114 (2012-11-14)
Cadmium (Cd(2+)) is a common environmental pollutant present in wastes associated with mining, smelting and electroplating. It is a major constituent of the tobacco smoke. Exposure of this heavy metal has been linked to wide range of detrimental effects on
Abdulwadood Shakir Mahmood Alsoufi et al.
Molecules (Basel, Switzerland), 24(16) (2019-08-14)
The aim of the study was the evaluation of the efficiency of selected abiotic elicitors, i.e., silver and cadmium ions, ultrasound, and UV-C irradiation, in the stimulation of triterpenoid biosynthesis, accumulation, and saponin secretion in Calendula officinalis hairy root cultures.
A A Fouad et al.
Andrologia, 47(4), 417-426 (2014-04-17)
The protective effect of thymoquinone was investigated against cadmium-induced testicular toxicity in rats. Testicular toxicity was induced by a single intraperitoneal (i.p.) injection of cadmium chloride (2 mg kg(-1) ). Thymoquinone treatment (10 mg kg(-1)  day(-1) , i.p.) was applied for five consecutive days
Samanta R Zanetti et al.
Biochimica et biophysica acta, 1841(1), 151-161 (2013-10-15)
Cadmium is known to harm rat testis by causing the dose-dependent apoptotic or necrotic death of seminiferous epithelium cells. Here we investigated how this affects the lipids with long-chain (C18-C22) and very-long-chain (C24-C32) polyunsaturated fatty acids (VLCPUFA) typical of spermatogenic
V Alexandra Moser et al.
iScience, 24(11), 103238-103238 (2021-11-09)
Apolipoprotein E4 (APOE4) is the strongest genetic risk factor for sporadic Alzheimer's disease (AD). APOE4 is known to affect the function of microglia, but to what extent this gene drives microglial gene expression has thus far not been examined. Using
Yanhong Lou et al.
Ecotoxicology (London, England), 22(2), 207-214 (2012-11-15)
Cadmium (Cd) and lead (Pb) are regarded as the most toxic environmental pollutants because they are a threat not only to plants, but also to humans. Better understanding of the growth response, uptake and translocation of Cd and Pb in
Joshua R Edwards et al.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 26(1), 33-42 (2012-10-20)
The E-cadherin/β-catenin complex is a structural component of adherens-type junctions in epithelial cells. Moreover, β-catenin acts as an intracellular signaling molecule that can influence the expression of a variety of genes that regulate apoptosis and cell cycle control. Cadmium (Cd)
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