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221198

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Marwa Ahmed et al.
Journal of chromatography. A, 1360, 100-109 (2014-08-19)
Single-walled carbon nanotubes were encapsulated into different polymer-based monolithic backbones. The polymer monoliths were prepared via the copolymerization of 20% monomers, glycidyl methacrylate, 20% ethylene glycol dimethacrylate and 60% porogens (36% 1-propanol, 18% 1,4-butanediol) or 16.4% monomers (16% butyl methacrylate...
Edith R Valle et al.
Canadian journal of microbiology, 61(6), 417-428 (2015-04-30)
In this study, methanogen-specific coenzyme F420 autofluorescence and confocal laser scanning microscopy were used to identify rumen methanogens and define their spatial distribution in free-living, biofilm-, and protozoa-associated microenvironments. Fluorescence in situ hybridization (FISH) with temperature-controlled hybridization was used in...
Elaine F da Silva et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 102, 71-74 (2012-12-12)
The formamide (FA)/pyridine (py)/pyridazine (prd) system was investigated by FT-Raman spectroscopy and the results in situ show that FA is preferentially bound to py, as experimentally pointed out by the proton affinity (PA) values of these azabenzenes. Temperature-dependent further investigations...
Lauren E Chun et al.
Journal of biological rhythms, 30(5), 417-436 (2015-08-15)
The molecular circadian clock is a self-regulating transcription/translation cycle of positive (Bmal1, Clock/Npas2) and negative (Per1,2,3, Cry1,2) regulatory components. While the molecular clock has been well characterized in the body's master circadian pacemaker, the hypothalamic suprachiasmatic nucleus (SCN), only a...
Alvaro Piñero et al.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 31, 231-235 (2015-02-17)
The genetic diversity of Coxiella burnetii from 36 dairy cattle herds was determined by Multiple-Locus Variable number tandem repeats Analysis (MLVA), and genotypes from different sources (bulk-tank milk - BTM and surface dust) and sampling time (2009/10 and 2011/12) were...
M C Duryea et al.
Heredity, 115(3), 225-234 (2015-04-30)
The theory of island biogeography is most often studied in the context of oceanic islands where all island inhabitants are descendants from founding events involving migration from mainland source populations. Far fewer studies have considered predictions of island biogeography in...
Patrick J Wijchers et al.
Genome research, 25(7), 958-969 (2015-04-18)
Despite recent progress in genome topology knowledge, the role of repeats, which make up the majority of mammalian genomes, remains elusive. Satellite repeats are highly abundant sequences that cluster around centromeres, attract pericentromeric heterochromatin, and aggregate into nuclear chromocenters. These...
Miranda M Gray et al.
Molecular ecology, 23(24), 6011-6028 (2014-11-06)
Big bluestem (Andropogon gerardii) is an ecologically dominant grass with wide distribution across the environmental gradient of U.S. Midwest grasslands. This system offers an ideal natural laboratory to study population divergence and adaptation in spatially varying climates. Objectives were to:...
Raffaele Saladino et al.
Research in microbiology, 160(7), 441-448 (2009-06-30)
In pursuing the origin of informational polymers, we followed the assumption that their spontaneous formation could only have occurred: (i) if all the components were present at the same site and in the same reaction, and (ii) if the thermodynamics...
Zilin Nie et al.
Nature communications, 6, 5908-5908 (2015-01-09)
MALT1 is the only known paracaspase and is a critical mediator of B- and T-cell receptor signalling. The function of the MALT1 gene is subverted by oncogenic chimeric fusions arising from the recurrent t(11;18)(q21;q21) aberration, which is the most frequent...
James Whitworth et al.
European journal of human genetics : EJHG, 23(5), 581-587 (2014-09-25)
Multiple primary malignant tumours (MPMT) are frequently taken as an indicator of potential inherited cancer susceptibility and occur at appreciable frequency both among unselected cancer patients and, particularly, among referrals to cancer genetics services. However, there is a paucity of...
Chang Hee Kim et al.
The Journal of molecular diagnostics : JMD, 17(2), 118-127 (2015-02-17)
We describe a novel method, based on target-dependent chemical ligation of probes, which simplifies the multiplexed quantitation of gene expression from blood samples by eliminating the RNA purification step. Gene expression from seven genes was evaluated over a range of...
Shuji Takabayashi et al.
Primates; journal of primatology, 56(3), 235-240 (2015-03-26)
The common marmoset (Callithrix jacchus) is a New World primate that is a useful model for medical studies. In this study, we report a convenient, reliable, and noninvasive procedure to genotype a living common marmoset by using fingernails. This method...
Ileana Vigentini et al.
Microbiology (Reading, England), 161(Pt 2), 362-373 (2014-12-07)
A three year survey on the dominant yeast populations in samples of air, must and wine in different vineyards and cellars of two northern Italian vine-growing territories (six sites in Franciacorta and eight sites in Oltrepò Pavese areas) was carried...
Jodie Birch et al.
American journal of physiology. Lung cellular and molecular physiology, 309(10), L1124-L1137 (2015-09-20)
Cellular senescence has been associated with the structural and functional decline observed during physiological lung aging and in chronic obstructive pulmonary disease (COPD). Airway epithelial cells are the first line of defense in the lungs and are important to COPD...
Laureen Jacquet et al.
PloS one, 10(5), e0126860-e0126860 (2015-05-21)
Huntington disease (HD; OMIM 143100), a progressive neurodegenerative disorder, is caused by an expanded trinucleotide CAG (polyQ) motif in the HTT gene. Cardiovascular symptoms, often present in early stage HD patients, are, in general, ascribed to dysautonomia. However, cardio-specific expression...
Takeshi Taniguchi et al.
The Journal of general and applied microbiology, 61(5), 193-202 (2015-11-20)
Tamarix ramosissima is a tree species that is highly resistant to salt and drought. The Tamarix species survives in a broad range of environmental salt levels, and invades major river systems in southwestern United States. It may affect root-associated bacteria...
Benedetta Arnò et al.
Nature communications, 5, 5611-5611 (2014-11-27)
Microglia are observed in the early developing forebrain and contribute to the regulation of neurogenesis through still unravelled mechanisms. In the developing cerebral cortex, microglia cluster in the ventricular/subventricular zone (VZ/SVZ), a region containing Cxcl12-expressing basal progenitors (BPs). Here we...
Jiqing Wang et al.
Scientific reports, 5, 12347-12347 (2015-07-23)
WFIKKN2 may play a role in the regulation of muscle growth and development, but to date there have been no reports on the effect of variation in WFIKKN2 on growth and carcass traits in livestock. In this study, the effect...
Taru Lienemann et al.
BMC microbiology, 15, 131-131 (2015-07-02)
Salmonella enterica spp. enterica serotype Typhimurium (STM) is the most common agent of domestically acquired salmonellosis in Finland. Subtyping methods which allow the characterization of STM are essential for effective laboratory-based STM surveillance and for recognition of outbreaks. This study...
Emiko Yanokura et al.
Systematic and applied microbiology, 38(5), 305-314 (2015-05-27)
The species Bifidobacterium longum is currently divided into three subspecies, B. longum subsp. longum, B. longum subsp. infantis and B. longum subsp. suis. This classification was based on an assessment of accumulated information on the species' phenotypic and genotypic features....
Alessandro Andreucci et al.
Reproductive toxicology (Elmsford, N.Y.), 53, 33-38 (2015-02-11)
We investigated the association between cadmium in blood and the concentration of the prostate specific antigen (PSA) in semen, including the modifying effects of zinc or the CAG polymorphism in the androgen receptor (AR). Blood and semen samples were collected...
T Phaechamud et al.
Indian journal of pharmaceutical sciences, 77(1), 62-74 (2015-03-15)
The objective of this investigation was to prepare the shellac wax matrix tablets by fusion and molding technique incorporated with Lutrol in different ratios to modify the hydrophobicity of matrix tablet. The matrix tablets with single drug were loaded either...
Katarzyna Klonowska et al.
Scientific reports, 5, 10424-10424 (2015-05-23)
Only approximately 50% of all familial breast cancers can be explained by known genetic factors, including mutations in BRCA1 and BRCA2. One of the most extensively studied candidates for breast and/or ovarian cancer susceptibility is BARD1. Although it was suggested...
Linlin Zhang et al.
International journal of nanomedicine, 10, 2913-2924 (2015-05-02)
Our prior screening of microRNAs (miRs) identified that miR-199a-3p expression is reduced in osteosarcoma cells, one of the most common types of bone tumor. miR-199a-3p exhibited functions of tumor cell growth inhibition, suggesting the potential application of miR-199a-3p as an...
Li-Na Zhang et al.
Biochimica et biophysica acta, 1853(2), 522-534 (2014-12-17)
Regulation of mRNA decay plays a crucial role in the post-transcriptional control of cell growth, survival, differentiation, death and senescence. Deadenylation is a rate-limiting step in the silence and degradation of the bulk of highly regulated mRNAs. However, the physiological...
Xin Deng et al.
Journal of bacteriology, 196(14), 2499-2513 (2014-04-29)
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from human pathogens Staphylococcus aureus and Pseudomonas aeruginosa can be readily inhibited by reactive oxygen species (ROS)-mediated direct oxidation of their catalytic active cysteines. Because of the rapid degradation of H2O2 by bacterial catalase, only steady-state but...
Sophie Badie et al.
The EMBO journal, 34(3), 410-424 (2015-01-15)
Loss of telomere protection occurs during physiological cell senescence and ageing, due to attrition of telomeric repeats and insufficient retention of the telomere-binding factor TRF2. Subsequently formed telomere fusions trigger rampant genomic instability leading to cell death or tumorigenesis. Mechanistically...
Yan-Ying Zhang et al.
Ecotoxicology (London, England), 24(7-8), 1467-1477 (2015-04-03)
Coral associated bacterial community potentially has functions relating to coral health, nutrition and disease. Culture-free, 16S rRNA based techniques were used to compare the bacterial community of coral tissue, mucus and seawater around coral, and to investigate the relationship between...
Xingmei Xie et al.
PloS one, 9(9), e106307-e106307 (2014-09-11)
Sex chromosome aneuploidies occur commonly in the general population, with an incidence of 1 in 400 newborns. However, no tests specifically targeting sex chromosomes have been carried out in prenatal diagnosis or newborn screening, resulting in late recognition of these...
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