Showing 1-30 of 65 results for "234192"
Different ligand exchange solvents effect on the densification of CuIn0. 7Ga0. 3Se2 prepared using the heating-up method
Yang C and Hsiang H
Applied Surface Science, 426(2), 1148-1157 (2017)
Shufeng Liu et al.
Chemistry, an Asian journal, 10(9), 1903-1908 (2015-07-16)
DNA three-way junctions (DNA 3WJ) have been widely used as important building blocks for the construction of DNA architectures and dynamic assemblies. Herein, we describe for the first time a catalytic hairpin assembly-programmed DNA three-way junction (CHA-3WJ) strategy for the...
Yingning Zheng et al.
Analytica chimica acta, 834, 45-50 (2014-06-15)
Our present work aimed at developing a pseudo triple-enzyme cascade electrocatalytic electrochemical aptasensor for determination of thrombin with the amplification of alcohol dehydrogenase (ADH)-Pt-Pd nanowires bionanocomposite and hemin/G-quadruplex structure that simultaneously acted as NADH oxidase and HRP-mimicking DNAzyme. With the...
Bridget S Penman et al.
British journal of haematology, 169(1), 117-128 (2014-12-19)
Genetic disorders of haemoglobin, particularly the sickle cell diseases and the alpha and beta thalassaemias, are the commonest inherited disorders worldwide. The majority of affected births occur in low-income and lower-middle income countries. Screening programmes are a vital tool to...
Baoting Dou et al.
The Analyst, 140(17), 5981-5986 (2015-07-17)
By coupling target DNA-induced reconfiguration of the dsDNA probes with enzyme-assisted target recycling amplification, we describe the development of a signal-on electrochemical sensing approach for sensitive detection of hereditary tyrosinemia type I gene. The dsDNA probes are self-assembled on the...
Christopher Redwood et al.
Photochemistry and photobiology, 91(3), 607-615 (2014-10-21)
cis-1,2-Di(1-methyl-2-naphthyl)ethene, c-1,1, undergoes photoisomerization in methylcyclohexane, isopentane and diethyl ether/isopentane/ethanol glasses at 77 K. On 313 nm excitation the fluorescence of c-1,1 is replaced by fluorescence from t-1,1. Singular value decomposition reveals that the spectral matrices behave as two component...
N Yasaka et al.
Journal of dermatological science, 7(2), 136-141 (1994-04-01)
The cutaneous basement membrane zone (BMZ) is composed of a large number of molecular components. We have recently reported that one of the CD1b monoclonal antibodies (MoAb), NU-T2, reacts to the BMZ of the normal human skin, esophagus and stomach....
Qing Zhou et al.
Lab on a chip, 15(23), 4467-4478 (2015-10-20)
Tissue injury triggers complex communication between cells via secreted signaling molecules such as cytokines and growth factors. Discerning when and where these signals begin and how they propagate over time is very challenging with existing cell culture and analysis tools....
T Hashimoto et al.
The British journal of dermatology, 134(2), 336-339 (1996-02-01)
In this study we present a patient with the sublamina densa type of linear IgA bullous dermatosis (LABD), with IgA autoantibodies reactive with the 290-kDa type VII collagen (the epidermolysis bullosa acquisita (EBA) antigen) and with immunoblotting of normal human...
Yoshinori Aso et al.
eLife, 3, e04580-e04580 (2014-12-24)
Animals discriminate stimuli, learn their predictive value and use this knowledge to modify their behavior. In Drosophila, the mushroom body (MB) plays a key role in these processes. Sensory stimuli are sparsely represented by ∼2000 Kenyon cells, which converge onto...
Justin D Besant et al.
Nature communications, 6, 6978-6978 (2015-04-23)
Diagnosis of disease outside of sophisticated laboratories urgently requires low-cost, user-friendly devices. Disposable, instrument-free testing devices are used for home and physician office testing, but are limited in applicability to a small class of highly abundant analytes. Direct, unambiguous visual...
Anyi Chen et al.
Analytical chemistry, 87(12), 6328-6334 (2015-05-15)
A target induced cycling strand displacement amplification (SDA) mediated by phi29 DNA polymerase (phi29) was first investigated and applied in a signal-off electrochemiluminescence (ECL) biosensor for microRNA (miRNA) detection. Herein, the target miRNA triggered the phi29-mediated SDA which could produce...
J Calvez et al.
Genes, brain, and behavior, 14(7), 550-563 (2015-08-04)
Relaxin-3 (RLN3) is an orexigenic neuropeptide that produces sex-specific effects on food intake by stronger stimulation of feeding in female compared with male rats. This study determined which hypothalamic nuclei and associated neuropeptides may be involved in the sex-specific orexigenic...
Simon Thebault et al.
PloS one, 10(6), e0129555-e0129555 (2015-06-20)
Type 1 narcolepsy is caused by deficiency of hypothalamic orexin/hypocretin. An autoimmune basis is suspected, but no specific antibodies, either causative or as biomarkers, have been identified. However, the AS03 adjuvanted split virion H1N1 (H1N1-AS03) vaccine, created to protect against...
Eun Ran Kim et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(29), 10440-10450 (2015-07-24)
The hypothalamus is critical for feeding and body weight regulation. Prevailing studies focus on hypothalamic neurons that are defined by selectively expressing transcription factors or neuropeptides including those expressing proopiomelanocortin (POMC) and agouti-related peptides (AgRP). The Cre expression driven by...
Mohamed A A Kassem et al.
AAPS PharmSciTech, 16(3), 537-547 (2014-11-06)
This work aims to prepare sustained release buccal mucoadhesive lyophilized chitosan sponges of buspirone hydrochloride (BH) to improve its systemic bioavailability. Chitosan sponges were prepared using simple casting/freeze-drying technique according to 3(2) factorial design where chitosan grade was set at...
Dan Zhu et al.
Nanoscale, 7(44), 18671-18676 (2015-10-27)
Enzyme complexes are assembled at the two-dimensional lipid membrane or prearranged on three-dimensional scaffolding proteins to regulate their catalytic activity in cells. Inspired by nature, we have developed gold nanoparticle-based spherical DNAzymes (SNAzymes) with programmably engineered activities by exploiting poly-adenine...
Anupama Tyagi et al.
Prostaglandins, leukotrienes, and essential fatty acids, 91(6), 289-297 (2014-12-03)
Imbalances in the dietary n-6 and n-3 polyunsaturated fatty acids have been implicated in the increased prevalence of inflammatory bowel disease. This study investigated the effects of substitution of linoleic acid with long chain n-3 polyunsaturated fatty acids and hence...
S M Jeong et al.
Oncogene, 34(16), 2115-2124 (2014-06-10)
Iron metabolism is essential for many cellular processes, including oxygen transport, respiration and DNA synthesis, and many cancer cells exhibit dysregulation in iron metabolism. Maintenance of cellular iron homeostasis is regulated by iron regulatory proteins (IRPs), which control the expression...
Yoon-Jung Choy et al.
Journal of chemical neuroanatomy, 66-67, 10-18 (2015-04-11)
Neuroinflammation is an early event and important contributor to the pathobiology of neurodegenerative diseases. Neuroglia, especially microglia, are a major central nervous system population that can modulate neuroinflammation. To determine potential key molecules in this process, we employed microarray analysis...
M Chen et al.
The Journal of investigative dermatology, 108(1), 68-72 (1997-01-01)
Epidermolysis bullosa acquisita (EBA) is an acquired blistering skin disease characterized by the presence of IgG autoantibodies to type VII collagen. EBA autoantibodies recognize four major immunodominant epitopes localized within the amino-terminal, noncollagenous (NC1) domain. In this study, we developed...
Yichun Shuai et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(48), E6663-E6672 (2015-12-03)
Recent studies have identified molecular pathways driving forgetting and supported the notion that forgetting is a biologically active process. The circuit mechanisms of forgetting, however, remain largely unknown. Here we report two sets of Drosophila neurons that account for the...
K Ercis et al.
Environmental science and pollution research international, 22(16), 12534-12543 (2015-04-24)
In the present study, changes in erythrocyte rheology in association with mercury toxicity and the role of propolis were analyzed in rats. Forty male Wistar Albino rats that were 4-5 months old were used in the study. The control group...
Ding Jiang et al.
The Analyst, 140(18), 6404-6411 (2015-08-08)
Silver nanoparticles (NPs) decorated nitrogen doped graphene (NG) nanocomposites were prepared through a one-step thermal-treatment route using arginine as the nitrogen source. By integrating the excellent electrical properties and large surface area of Ag NPs and NG, the obtained Ag/NG...
Tan, C. S.; Lim, D. F.; Singh, S. G.; Goulet, S. K.; Bergkvist, M.
Applied Physics Letters, 91, 192108-192108 (2007)
Fallon Cook et al.
BMC pediatrics, 15, 174-174 (2015-11-12)
Anticipatory guidance around the management of sleep and crying problems in early infancy has been shown to improve both infant behaviour and parent symptoms of postnatal depression. Digital technology offers platforms for making such programs widely available in a cost-efficient...
John Apergis-Schoute et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(14), 5435-5441 (2015-04-10)
The lateral hypothalamus (LH) is a key regulator of multiple vital behaviors. The firing of brain-wide-projecting LH neurons releases neuropeptides promoting wakefulness (orexin/hypocretin; OH), or sleep (melanin-concentrating hormone; MCH). OH neurons, which coexpress glutamate and dynorphin, have been proposed to...
Arega Tsegaye et al.
Malaria journal, 13, 438-438 (2014-11-20)
Glucose-6-phosphate dehydrogenase deficiency (G6PDd) is widespread across malaria endemic regions. G6PD-deficient individuals are at risk of haemolysis when exposed, among other agents, to primaquine and tafenoquine, which are capable of blocking malaria transmission by killing Plasmodium falciparum gametocytes and preventing...
Xiang Huang et al.
The Analyst, 140(17), 6015-6024 (2015-07-21)
An efficient aptasensor was developed in which graphene oxide (GO) was employed as an indicator for both electrochemical impedance spectroscopy and electrochemiluminescence (ECL) signal generation. The aptasensor was fabricated by self-assembling the ECL probe of a thiolated adenosine triphosphate binding...
Noble metal surface degradation induced by organothiols
de Poel W, et al.
Surface Science, 662, 59-66 (2017)

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon


Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.