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Biao Gu et al.
The Analyst, 140(8), 2778-2784 (2015-02-27)
A novel ratiometric fluorescent Hg(2+) detecting system was rationally developed based on the typical excited state intramolecular proton transfer (ESIPT) characteristic of the latent fluorophore, 2-(1-(p-tolyl)-1H-phenanthro[9,10-d]imidazol-2-yl)phenol (Pol) and the Hg(2+)-mediated cleavage of the vinyl group. The probe responds selectively to
James K Henderson et al.
Journal of contaminant hydrology, 108(1-2), 29-45 (2009-06-19)
An analytical model is used to simulate the effects of partial source removal and plume remediation on ethylene dibromide (EDB) and 1,2-dichloroethane (1,2-DCA) plumes at contaminated underground storage tank (UST) sites. The risk posed by EDB, 1,2-DCA, and commingled gasoline
Frida Jonsson et al.
Human mutation, 36(4), 463-473 (2015-02-14)
Corneal dystrophies are a clinically and genetically heterogeneous group of inherited disorders that bilaterally affect corneal transparency. They are defined according to the corneal layer affected and by their genetic cause. In this study, we identified a dominantly inherited epithelial
Elisabeth M Loecken et al.
Chemical research in toxicology, 21(2), 453-458 (2008-01-01)
The environmental contaminant 1,2-dibromoethane and diepoxybutane, an oxidation product of the important industrial chemical butadiene, are bis-functional electrophiles and are known to be mutagenic and carcinogenic. One mechanism by which bis-electrophiles can exert their toxic effects is through the induction
Kengo Watanabe et al.
Chemical research in toxicology, 20(11), 1594-1600 (2007-10-03)
Dihaloalkanes are of toxicological interest because of their high-volume use in industry and their abilities to cause tumors in rodents, particularly dichloromethane and 1,2-dichloroethane. The brominated analogues are not used as extensively but are known to produce more toxicity in
Katerina Papezová et al.
Journal of chromatography. A, 1150(1-2), 327-331 (2006-10-03)
Substrate inhibition is a common phenomenon in enzyme kinetics. We report here for the first time its study by a combination of the electrophoretically mediated microanalysis (EMMA) methodology with a partial filling technique. In this setup, the part of capillary
Yang Zhang et al.
Dalton transactions (Cambridge, England : 2003), 44(29), 13100-13111 (2015-06-25)
We have recently demonstrated that complexation with (η(6)-arene)Ru(II) fragments confers 4-anilinoquinazoline pharmacophores a higher potential for inducing cellular apoptosis while preserving the highly inhibitory activity of 4-anilinoquinazolines against EGFR and the reactivity of the ruthenium centre to 9-ethylguanine (Chem. Commun.
Tao Chen et al.
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 41(4), 700-702 (2010-09-21)
To design and synthesize novel peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. A series of novel PPARgamma agonists were designed based on the binding character of PPARgamma agonists and the distribution of pharmacophore. The target compounds were synthesized using p-hydroxybenzaldehyde, 1
Julian Renpenning et al.
Rapid communications in mass spectrometry : RCM, 31(13), 1095-1102 (2017-04-05)
The conventional high-temperature conversion (HTC) approach towards hydrogen compound-specific isotope analysis (CSIA) of halogen-bearing (F, Cl, Br, I) organics suffers from incomplete H The performance of the modified gas chromatography/chromium-based high-temperature conversion (GC-Cr/HTC) system was monitored and optimized using an
Ethylene dibromide (1,2-dibromoethane).
IARC monographs on the evaluation of carcinogenic risks to humans, 71 Pt 2, 641-669 (1999-09-07)
Yoen Jung Lee et al.
Molecules and cells, 33(3), 309-316 (2012-03-22)
To identify specific biomarkers generated upon exposure of L5178Y mouse lymphoma cells to carcinogens, 2-DE and MALDI-TOF MS analysis were conducted using the cellular proteome of L5178Y cells that had been treated with the known carcinogens, 1,2-dibromoethane and O-nitrotoluene and
Annamaria Colacci et al.
Toxicology in vitro : an international journal published in association with BIBRA, 25(6), 1183-1190 (2011-06-16)
Cell transformation assays (CTAs) are currently regarded as the only possible in vitro alternative to animal testing for carcinogenesis studies. CTAs have been proposed as screening tests for the carcinogenic potential of compounds that have no evidence of genotoxicity but
Ali Akbar Alizadeh Nabil et al.
Biomedical chromatography : BMC, 29(7), 1094-1102 (2014-12-18)
This paper presents a fast and simple method for the extraction, preconcentration and determination of fluvoxamine, nortriptyline and maprotiline in urine using simultaneous derivatization and temperature-assisted dispersive liquid-liquid microextraction (TA-DLLME) followed by gas chromatography-flame ionization detection (GC-FID). An appropriate mixture
Yoen Jung Lee et al.
Molecules and cells, 33(2), 203-210 (2012-02-24)
1,2-Dibromoethane and glycidol are well known genotoxic carcinogens, which have been widely used in industry. To identify a specific biomarker for these carcinogens in cells, the cellular proteome of L5178Y mouse lymphoma cells treated with these compounds was analyzed by
Ngoc-Duc Doan et al.
Biopolymers, 104(5), 629-635 (2015-03-20)
The conformation of the N-amino-imidazolidin-2-one (Aid) peptidomimetic was investigated using NMR spectroscopy and X-ray crystallography. In solution, the tetrapeptide model p-bromobenzoyl-Aid-l-Phe-N'-iso-propylamide (1) exhibited shielded and solvent exposed amide protons indicative of a turn conformation. In the crystal lattice of 1
Saturation vapor pressures and transition enthalpies of low-volatility organic molecules of atmospheric relevance: from dicarboxylic acids to complex mixtures.
Merete Bilde et al.
Chemical reviews, 115(10), 4115-4156 (2015-05-02)
James K Henderson et al.
Environmental science & technology, 42(3), 864-870 (2008-03-08)
Field evidence from underground storage tank sites where leaded gasoline leaked indicates the lead scavengers 1,2-dibromoethane (ethylene dibromide, or EDB) and 1,2-dichloroethane (1,2-DCA) may be present in groundwater at levels that pose unacceptable risk. These compounds are seldom tested for
1, 2-dibromoethane-A versatile reagent in organic synthesis
Aluri BR
Synlett, 2008(10), 1579-1580 (2008)
Report on carcinogens : carcinogen profiles, 12, 135-138 (2011-08-20)
Simple and efficient protocol for the synthesis of functionalized styrenes from 1, 2-dibromoethane and arylboronic acids
Lando VR and Monteiro AL
Organic Letters, 5(16), 2891-2894 (2003)
Genotoxic effects of 1,2-dibromoethane and 1,2-dichloroethane.
U Rannug
Mutation research, 76(3), 269-295 (1980-11-01)
1, 2-Dibromoethane
Maynard GD
Encyclopedia of Reagents for Organic Synthesis, Second Edition (2001)
Mir Ali Farajzadeh et al.
Analytica chimica acta, 885, 122-131 (2015-08-02)
In this paper, a new version of salting-out homogenous liquid-liquid extraction based on counter current mode combined with dispersive liquid-liquid microextraction has been developed for the extraction and preconcentration of some pesticides from aqueous samples and their determination by gas
Gaolei Wang et al.
Journal of agricultural and food chemistry, 63(31), 6883-6889 (2015-07-07)
A series of novel 1,2,3-benzotriazin-4-one derivatives were synthesized by the reaction of 3-bromoalkyl-1,2,3-benzotriazin-4-ones with potassium salt of 2-cyanoimino-4-oxothiazolidine in the presence of potassium iodide. Nematicidal assays in vivo showed that some of them exhibited good control efficacy against the cucumber
Neelima Singh et al.
The Journal of the Association of Physicians of India, 55, 842-845 (2008-04-15)
In view of high incidence and mortality due to ethylene dibromide poisoning, a prospective study was planned to assess demographic, toxicological, clinical profile and outcome. Prospectively collected data of sixty four patients with ethylene dibromide poisoning were reviewed. All the
Tomasz Kuder et al.
Environmental science & technology, 46(14), 7495-7502 (2012-06-09)
EDB (1,2-dibromoethane) is frequently detected at sites impacted by leaded gasoline. In reducing environments, EDB is highly susceptible to abiotic degradation. A study was conducted to evaluate the potential of compound-specific isotope analysis (CSIA) in assessing abiotic degradation of EDB
Monique T Binet et al.
Environmental toxicology and chemistry, 29(9), 1984-1993 (2010-09-08)
As part of a larger study investigating the fate and effects of brominated volatile organic compounds (VOCs) in contaminated groundwaters discharging to surface waters, the toxicity of 1,2 dibromoethene (DBE) and 1,1,2-tribromoethene (TriBE) to freshwater aquatic biota was investigated. Their
Alfonso Pérez-Garrido et al.
Bioorganic & medicinal chemistry, 16(10), 5720-5732 (2008-04-15)
The risk of the presence of haloacetic acids in drinking water as chlorination by-products and the shortage of experimental mutagenicity data for most of them requires a research work. This paper describes a QSAR model to predict direct mutagenicity for
Oksana Degtjarik et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 69(Pt 3), 284-287 (2013-03-23)
Haloalkane dehalogenases are microbial enzymes that convert a broad range of halogenated aliphatic compounds to their corresponding alcohols by the hydrolytic mechanism. These enzymes play an important role in the biodegradation of various environmental pollutants. Haloalkane dehalogenase LinB isolated from
Maryam Ebrahimi et al.
Journal of the American Chemical Society, 133(41), 16560-16565 (2011-09-02)
Adsorbates on metals, but not previously on semiconductors, have been observed to display long-range repulsive interactions. On metals, due to efficient dissipation, the repulsions are weak, typically on the order of 5 meV at 10 Å. On the 7×7 reconstruction
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