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Eagleson M.
Concise Encyclopedia Chemistry, 887-887 (1994)
M Piga et al.
Minerva endocrinologica, 33(3), 213-228 (2008-10-11)
Amiodarone (AM), a potent class III anti-arrhythmic drug, is an iodine-rich compound with a structural resemblance to thyroid hormones triiodothyronine (T3) and thyroxine (T4). At the commonly employed doses, AM causes iodine overload up to 50-100 times the optimal daily
Marta Bellotti et al.
Bioorganic & medicinal chemistry, 23(1), 22-32 (2014-12-17)
The phytohormone abscisic acid (ABA), in addition to regulating physiological functions in plants, is also produced and released by several mammalian cell types, including human granulocytes, where it stimulates innate immune functions via an increase of the intracellular cAMP concentration
F Bogazzi et al.
Journal of endocrinological investigation, 27(5), 430-435 (2004-07-29)
Pendred syndrome and the enlarged vestibular aqueduct (EVA) are considered phenotypic variations of the same entity due to mutations in the SLC26A4 (pendrin) gene. Pendred syndrome consists in sensorineural deafness, goiter and impaired thyroid hormone synthesis while in EVA thyroid
S Salina M Stilborn et al.
General and comparative endocrinology, 183, 63-68 (2013-01-09)
Thyroid hormones (THs) are crucial for normal vertebrate development and are the one obligate morphogen that drives amphibian metamorphosis. However, contrary to other metamorphosing vertebrates, lampreys exhibit a sharp drop in serum TH early in metamorphosis, and anti-thyroid agents such
Thyroid protection before 123I-ioflupane (DaTSCAN) imaging.
Yvan Mouraeff et al.
European journal of nuclear medicine and molecular imaging, 38(4), 786-787 (2011-01-29)
Benedicte Thienpont et al.
Environmental science & technology, 45(17), 7525-7532 (2011-08-02)
Thyroxine-immunofluorescence quantitative disruption test (TIQDT) was designed to provide a simple, rapid, alternative bioassay for assessing the potential of chemical pollutants and drugs to disrupt thyroid gland function. This study demonstrated that zebrafish eleutheroembryos provided a suitable vertebrate model, not
María Inés Carmona-López et al.
Endocrine research, 37(4), 188-196 (2012-05-29)
A study was conducted on histological patterns and biomolecular changes in Goitrogen-induced experimental rat thyroid tumors. The link between the histological types observed and N-ras, B-raf, and PI3KCA gene mutations widely reported in human thyroid cancers was explored. An analysis
Nieves Arias et al.
Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 58(3), 121-126 (2011-03-04)
Amiodarone-induced thyrotoxicosis (AIT) is a common clinical disorder that may be life threatening and whose clinical manifestations and response to treatment may vary among patients. We present three patients treated with amiodarone for atrial fibrillation who developed AIT at least
J D Méndez-Díaz et al.
Water research, 43(6), 1621-1629 (2009-01-17)
The present study investigates the efficacy of various oxidizing treatments (ClO(-), ClO(2), KMnO(4), O(3), O(3)/H(2)O(2), O(3)/activated carbon) to remove from waters sodium dodecylbenzenesulphonate (SDBS), considered as model surfactant. Results obtained show that the use of ClO(-) and ClO(2) does not
F Bogazzi et al.
Journal of endocrinological investigation, 31(6), 515-519 (2008-07-02)
Amiodarone-induced hypothyroidism (AIH) may occur in patients with or without underlying thyroid disorders. In the latter, restoration of euthyroidism, after amiodarone discontinuation, can be facilitated and accelerated by a short course of potassium perchlorate (KClO4). However, it is unknown whether
Lin Shao-Qin et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 62(1-3), 637-640 (2005-11-01)
A new method for the determination of trace aluminum has been proposed. It is based on the fact that alizarin red can emit strong and stable fluorescence at 80 degrees C for 30 min and Al(3+) can effectively catalyze potassium
G Coelho-Palermo Cunha et al.
Regulatory toxicology and pharmacology : RTP, 48(3), 270-278 (2007-06-19)
The perchlorate discharge assay (PDA) is potentially of high diagnostic value to distinguish between direct and indirect thyroid toxicity mechanisms, provided that standard treatment times are established and positive controls yield reproducible results. Therefore the PDA was evaluated after 2
F Bogazzi et al.
Journal of endocrinological investigation, 29(1), 61-66 (2006-03-24)
Amiodarone perturbs thyroid function, causing overt hypothyroidism or hyperthyroidism in 15% of patients. Changes in thyroid function are likely due, at least in part, to amiodarone and/or desethylamiodarone (DEA) concentration into the thyroid gland, but mechanisms whereby the drug uptake
J M Fernández-Santos et al.
Journal of endocrinological investigation, 27(1), 12-17 (2004-04-01)
Although in both human and experimental pathology ras mutations have been related to the origin and progression of follicular-cell tumours, reports differ considerably with respect to the frequency of such mutations. The present paper reports, using direct sequencing, the incidence
Eagleson M.
Concise Encyclopedia Chemistry, 790-790 (1994)
Florian Schmidt et al.
Aquatic toxicology (Amsterdam, Netherlands), 109, 47-58 (2011-12-30)
The increasing pollution of aquatic habitats with anthropogenic compounds has led to various test strategies to detect hazardous chemicals. However, information on effects of pollutants in the thyroid system in fish, which is essential for growth, development and parts of
Angela R Buckalew et al.
Archives of toxicology, 94(3), 873-885 (2020-02-18)
The Fischer rat thyroid follicular cell line (FRTL-5) endogenously expresses the sodium-iodide symporter (NIS) and has been used to identify environmental chemicals that perturb thyroid hormone homeostasis by disruption of NIS-mediated iodide uptake. Previously, a high-throughput radioactive iodide uptake (RAIU)
Perchlorate from fireworks.
Rhitu Chatterjee
Environmental science & technology, 41(11), 3792-3793 (2007-07-07)
Baohua Gu et al.
Environmental science & technology, 41(17), 6277-6282 (2007-10-17)
Treatment of perchlorate-contaminated water using highly selective, regenerable ion-exchange and perchlorate-destruction technologies was demonstrated at a field site in California. Four treatment and four regeneration cycles were carried out, and no significant deterioration of resin performance was noted in 2
Thomas M Klapötke et al.
Angewandte Chemie (International ed. in English), 53(36), 9665-9668 (2014-07-22)
The generation of blue-light-emitting pyrotechnic formulations without the use of chlorine-containing compounds is reported. Suitable blue-light emission has been achieved through the generation of molecular emitting copper(I) iodide. The most optimal copper(I) iodide based blue-light-emitting formulation was found to have
Eric M Brown et al.
Cell host & microbe, 25(5), 668-680 (2019-05-10)
Sphingolipids are structural membrane components and important eukaryotic signaling molecules. Sphingolipids regulate inflammation and immunity and were recently identified as the most differentially abundant metabolite in stool from inflammatory bowel disease (IBD) patients. Commensal bacteria from the Bacteroidetes phylum also
Grazyna Bednarek-Tupikowska et al.
Postepy higieny i medycyny doswiadczalnej (Online), 58, 216-225 (2004-04-29)
Amiodarone is an iodine-rich drug. Its chronic administration may lead to disturbances in thyroid hormone metabolism and/or overt gland dysfunction. It causes an increased in serum fT4, rT3, and TSH concentrations and a decreased serum level of fT3 without thyroid
Patrick D Barnett et al.
Applied spectroscopy, 71(6), 1380-1386 (2016-12-14)
This work describes a method of applying the Fourier transform to the two-dimensional Fizeau fringe patterns generated by the spatial heterodyne Raman spectrometer (SHRS), a dispersive interferometer, to correct the effects of certain types of optical alignment errors. In the
Kwang Il Kim et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 11(1), 123-128 (2005-01-27)
To develop a gamma camera imaging method for the determination of endogenous gene expression, we evaluated the expression of endogenous p53 gene using human sodium iodide symporter (hNIS) gene as reporter. We constructed cis-p53RE-hNIS reporter vector placed under control of
F Lairion et al.
The journal of physical chemistry. B, 113(6), 1607-1614 (2009-02-06)
When the dipole potential of dimyristoylphosphatidylcholine (DMPC) monolayers was decreased, either by the insertion of phloretin or by the elimination of carbonyl groups at the interphase, the surface charge potential was displaced to lower negative values. At low ionic strength
M F Izaguirre et al.
Brazilian journal of biology = Revista brasleira de biologia, 68(3), 561-569 (2008-10-04)
Cell adhesion molecules act as signal transducers from the extracellular environment to the cytoskeleton and the nucleus and consequently induce changes in the expression pattern of structural proteins. In this study, we showed the effect of thyroid hormone (TH) inhibition
Evangelos Kalamaras et al.
Faraday discussions, 215(0), 329-344 (2019-04-04)
Utilising photoelectrochemical (PEC) devices to produce sustainable fuels from water and CO2 is a very attractive strategy, in which sunlight is used to convert the greenhouse gas (CO2) into a usable form of stored chemical energy. While significant progress has
Toshio Imai et al.
Toxicology letters, 185(3), 160-167 (2009-01-21)
Early life exposure to certain kinds of chemicals is of concern because of a possible increase in cancer risk, but relevant data are limited. In the present experiment, modifying effects of prepubertal administration of potassium perchlorate (KClO(4)) and tetrabromobisphenol A
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