Showing 1-30 of 397 results for "252476"
Malgorzata Szafirska et al.
Przeglad lekarski, 70(5), 328-334 (2013-08-16)
The aim of the study was the assessment of metabolic changes revealed in proton MR spectroscopy in plaques of white matter of MS patients. With the use of MR 1.5T system, 90 MS patients were performed single voxel spectroscopy (SVS)...
The venous saturation paradox: measure it early, but leave it alone afterward*.
Andre Carlos Kajdacsy-Balla Amaral
Critical care medicine, 41(6), 1572-1573 (2013-05-21)
Timothy L Turner et al.
Applied microbiology and biotechnology, 99(19), 8023-8033 (2015-06-06)
Production of lactic acid from renewable sugars has received growing attention as lactic acid can be used for making renewable and bio-based plastics. However, most prior studies have focused on production of lactic acid from glucose despite that cellulosic hydrolysates...
Anna Paula Brandt et al.
Chemico-biological interactions, 218, 107-114 (2014-05-20)
Previously, we demonstrated that sydnone SYD-1 (3-[4-chloro-3-nitrophenyl]-1,2,3-oxadiazolium-5-olate) impairs the mitochondrial functions linked to energy provision and suggested that this effect could be associated with its antitumor activity. Herein, we evaluated the effects of SYD-1 (25 and 50 μM) on rat...
Andrew O Jo et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(39), 13525-13537 (2015-10-02)
Brain edema formation occurs after dysfunctional control of extracellular volume partly through impaired astrocytic ion and water transport. Here, we show that such processes might involve synergistic cooperation between the glial water channel aquaporin 4 (AQP4) and the transient receptor...
Lisa Solieri et al.
Food microbiology, 51, 108-116 (2015-07-19)
This study aimed at evaluating non-starter lactobacilli (NSLAB) isolated from cheeses for their proteolytic activity and capability to produce fermented milk enriched in angiotensin-converting enzyme (ACE)-inhibitory and antioxidant peptides. Preliminarily, 34 NSLAB from Parmigiano Reggiano (PR) and 5 from Pecorino...
Leticia Liste-Calleja et al.
Applied microbiology and biotechnology, 99(23), 9951-9960 (2015-08-15)
One of the most important limitations of mammalian cell-based processes is the secretion and accumulation of lactate as a by-product of their metabolism. Among the cell lines commonly used in industrial bioprocesses, HEK293 has been gaining importance over the last...
Dandan Zhang et al.
Plant science : an international journal of experimental plant biology, 237, 24-32 (2015-06-20)
The RNaseIII enzyme Dicer-like 1 (DCL1) processes the microRNA biogenesis and plays a determinant role in plant development. In this study, we reported the function of OsDCL1 in the immunity to rice blast, the devastating disease caused by the fungal...
M G Desimio et al.
Cell cycle (Georgetown, Tex.), 14(7), 1036-1045 (2015-01-21)
As the name implies, Stimulated by Retinoic Acid 8 is an early retinoic acid (RA) responsive gene pivotal for the beginning of meiosis in female and male germ cells. Its expression is strictly time-dependent and cell-specific (pre-meiotic germ cells) and...
Núria Magrinyà et al.
International journal of food microbiology, 215, 86-94 (2015-09-08)
A minced meat model system containing three different fat levels (0, 15, and 50 wt.%) was used to evaluate the antimicrobial efficacy of three antimicrobials with different aqueous solubilities (sodium lactate>lauric arginate (Nα-lauroyl-L-arginine ethyl ester, LAE)>methylparaben). Various concentrations of sodium...
Jason D Wink et al.
Plastic and reconstructive surgery, 134(1), 51-59 (2014-03-14)
Commercially available recombinant human bone morphogenetic protein 2 (rhBMP2) has demonstrated efficacy in bone regeneration, but not without significant side effects. The authors used rhBMP2 encapsulated in poly(lactic-co-glycolic acid) (PLGA) microspheres placed in a rabbit cranial defect model to test...
Christopher Masterjohn et al.
Experimental biology and medicine (Maywood, N.J.), 238(4), 360-369 (2013-06-14)
Methylglyoxal (MGO) is a dicarbonyl that reacts with amino acids and nucleic acids to form advanced glycation endproducts, which may contribute to diabetes and its cardiovascular complications. MGO detoxification through the glyoxalase (GLO) pathway is glutathione (GSH)-dependent, but no studies...
M T P R Perera et al.
The British journal of surgery, 101(7), 775-783 (2014-04-29)
Donation after circulatory death (DCD) liver grafts have supplemented the donor organ pool, but certain adverse outcomes have prevented exploration of the full potential of such organs. The aim of this study was to determine key differences in basic energy...
Di Huang et al.
Bioresource technology, 196, 263-272 (2015-08-09)
Rhizopus oryzae is strictly inhibited by biodiesel-based by-product crude glycerol, which results in low fumaric acid production. In this study, evolutionary engineering was employed to activate the glycerol utilization pathway for fumaric acid production. An evolved strain G80 was selected...
Sandeep Kumar Misra et al.
Journal of proteome research, 13(12), 6046-6057 (2014-11-11)
Protein phosphorylation is a major mechanism of signal transduction in bacteria. Here, we analyzed the proteome and phosphoproteome of a wild-type strain of the food-borne pathogen Listeria monocytogenes that was grown in either chemically defined medium or rich medium containing...
Yuanming Ouyang et al.
Journal of biomedical nanotechnology, 9(6), 931-943 (2013-07-19)
An ideal nerve scaffold should supply structural guidance and trophic support to facilitate nerve regeneration. Aligned electrospun nanofibers have shown considerable promise for the precise guidance of regenerating axons in vitro and in vivo. Therefore, uniaxially aligned three-dimension (3D) nanofiberous...
Andrew Bivard et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 34(12), 1944-1950 (2014-10-02)
The aim of acute stroke treatment is to reperfuse the penumbra. However, not all posttreatment reperfusion is associated with a good outcome. Recent arterial spin labeling (ASL) studies suggest that patients with hyperperfusion after treatment have a better clinical recovery....
Ralph Fiore et al.
Journal of drugs in dermatology : JDD, 12(3), 353-357 (2013-04-03)
The emphasis on the preservation of youth is ever apparent as new antiaging products, cosmetic procedures, and advertising campaigns aim to address new ways to prevent the natural aging process. Many individuals prefer noninvasive surgical procedures involving minimal downtime and...
Zhonghua Liu et al.
Electrophoresis, 36(17), 2002-2016 (2015-06-04)
Fuzhuan brick tea has received increasing attention in recent years owing to its benefits for nonalcoholic fatty liver disease (NAFLD) and associated metabolic syndrome. For exploring the ameliorative mechanism, the liver proteomes from three groups of rats fed either a...
Tim J A Dekker et al.
Analytical and bioanalytical chemistry, 407(8), 2167-2176 (2014-11-10)
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging using 9-aminoacridine as the matrix leads to the detection of low mass metabolites and lipids directly from cancer tissues. These included lactate and pyruvate for studying the Warburg effect, as well as succinate...
Yuming Dong et al.
Pharmaceutical development and technology, 19(8), 960-967 (2013-12-11)
High concentration of 5-amino salicylic acid (5-ASA) in the distal ileum and colon is necessary for the treatment of inflammatory bowel disease (IBD). The control of small molecules, drugs, released from a polymeric matrix remains a great challenge. To study...
Annabelle Olsson et al.
Journal of wildlife diseases, 49(3), 560-567 (2013-06-20)
Using a prospective, randomized study design we demonstrate that midazolam sedation minimizes acidosis compared with physical restraint in captive juvenile estuarine crocodiles during handling or noninvasive procedures at preferred body temperature. A dose of midazolam (5.0 mg/kg) was administered intramuscularly...
E Litton et al.
Anaesthesia and intensive care, 43(1), 59-65 (2015-01-13)
Optimising perioperative haemodynamic status may reduce postoperative complications. In this prospective prevalence study, we investigated the associations between standard haemodynamic parameters and a low central venous oxygen saturation (ScvO2) in patients after major surgery. A total of 201 patients requiring...
Se-Kwon Moon et al.
Journal of industrial microbiology & biotechnology, 41(10), 1525-1531 (2014-08-29)
The by-products of bioethanol production such as thin stillage (TS) and condensed distillers solubles (CDS) were used as a potential nitrogen source for economical production of lactic acid. The effect of those by-products and their concentrations on lactic acid fermentation...
Dong-Hyeon Kim et al.
Journal of food protection, 78(9), 1651-1655 (2015-09-01)
Kefir is a type of fermented milk containing lactic and acetic acid bacteria and yeast. In this study, we evaluated the antimicrobial activity of kefir supernatant against Cronobacter sakazakii in powdered infant formula (PIF). In a spot-on-lawn test, the growth...
Qizhi Hu et al.
Biomaterials, 53, 370-378 (2015-04-22)
Treatment with chemotherapy such as docetaxel (DTX) is associated with significant toxicity and tumour recurrence. In this study, we developed DTX-entrapped core-cross-linked polymeric micelles (DTX-CCL-PMs, 66 nm size) by covalently conjugating DTX to CCL-PMs via a hydrolysable ester bond. The covalent...
Oystein Sylta et al.
International journal of sports physiology and performance, 9(1), 100-107 (2014-01-11)
The authors directly compared 3 frequently used methods of heart-rate-based training-intensity-distribution (TID) quantification in a large sample of training sessions performed by elite endurance athletes. Twenty-nine elite cross-country skiers (16 male, 13 female; 25 ± 4 y; 70 ± 11...
Xiaoxin Zheng et al.
Journal of biomedical nanotechnology, 10(6), 900-910 (2014-04-23)
Biodegradable polymers used as vascular stent coatings and stent platforms encounter a major challenge: biocompatibility in vivo, which plays an important role in in-stent restenosis (ISR). Co-formulating amorphous calcium phosphate (ACP) into poly(lactic-co-glycolic acid) (PLGA) or poly-L-lactic acid (PLLA) was...
Diane Chauliac et al.
Biotechnology letters, 37(12), 2411-2418 (2015-08-15)
A bio-based process is appealing for purification of L-lactic acid, the major enantiomer of polylactic acid syrup, generated by thermochemical processes at the end of life of PLA-based plastics, from its chiral impurity, D-lactic acid, before reuse. Polylactic acid (PLA)...
Fernanda Visioli et al.
PloS one, 9(6), e101053-e101053 (2014-06-26)
This study was designed to investigate the activation of the unfolded protein response (UPR) in tumor associated endothelial cells (TECs) and its association with chemoresistance during acidic pH stress. Endothelial cells from human oral squamous cell carcinomas (OSCC) were excised...

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