Showing 1-30 of 43 results for "268011"
Juan Jin et al.
New biotechnology, 28(2), 190-195 (2010-10-19)
The ability of free and immobilized lipase on the production of diacylglycerols (DAG) by transesterification of glycerol monooleate (GMO) and ethyl oleate was investigated. Among three free lipases such as lipase G (Penicillium cyclopium), lipase AK (Pseudomonas fluorescens) and lipase...
Velio Bocci et al.
Virulence, 1(3), 215-217 (2010-12-24)
A vaccine against HIV able to generate properly neutralizing antibodies and an efficacious cytotoxic T lymphocyte response is of paramount importance. We are proposing a novel approach based on the collection of thousand small HIV-infected human plasma samples for preparing...
Franco Cataldo
Chemistry and physics of lipids, 163(6), 524-529 (2010-03-27)
Unsaturated lipids when exposed to air at room temperature undergo a slow autoxidation. When fullerene C(60) was dissolved in selected lipids (ethyl oleate, ethyl linoleate, linseed oil and castor oil) the spectrophotometric analysis shows that the oxidation is concentrated to...
Qi Shen et al.
AAPS PharmSciTech, 12(4), 1044-1049 (2011-08-16)
In the present study, the effect of a borneol/menthol eutectic mixture (25:75) and microemulsion on the absorption of daidzein in rat intestinal membrane was evaluated. The microemulsion formulation was composed of ethyl oleate (oil), Cremophor RH40 (surfactant), PEG400 (co-surfactant), and...
Dehua Liao et al.
Drug delivery, 22(4), 516-521 (2014-01-29)
The aim of this research was to increase the oral bioavailability of puerarin by N-trimethyl chitosan-modified microemulsions (TMC-MEs) loaded with puerarin. Different concentrations of TMC-modified microemulsions were prepared in our study, and then evaluated for particle size, zeta potential, morphological...
Michael D Hardy et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(27), 8187-8192 (2015-06-24)
Cell membranes are dynamic structures found in all living organisms. There have been numerous constructs that model phospholipid membranes. However, unlike natural membranes, these biomimetic systems cannot sustain growth owing to an inability to replenish phospholipid-synthesizing catalysts. Here we report...
Sowmya S Mohan et al.
Alcoholism, clinical and experimental research, 39(3), 434-444 (2015-02-24)
Chronic alcohol exposure alters the function of alveolar macrophages (AM), impairing immune defenses in both adult and neonatal lungs. Fatty acid ethyl esters (FAEEs) are biological markers of prenatal alcohol exposure in newborns. FAEEs contribute to alcohol-induced mitochondrial (MT) damage...
Ping Li et al.
Acta pharmacologica Sinica, 31(7), 881-888 (2010-06-22)
To improve the oral absorption of adefovir dipivoxil (ADV) by employing MCT and the esterase inhibitor ethyl oleate (EO) as a complex oil phase in emulsion. EO was used as the esterase inhibitor, and its inhibitory effect on esterase activity...
Aihua Yu et al.
Journal of pharmaceutical sciences, 100(3), 933-941 (2010-09-24)
The main objective of the study was to investigate the efficacy of microemulsion (ME) to facilitate bioavailability of puerarin (PUE) after oral and nasal administration. The pseudo-ternary phase diagrams were constructed to screen the ME components and optimize the ME...
Subhankar Dolai et al.
Gastroenterology, 143(3), 832-843 (2012-06-20)
During development of alcoholic pancreatitis, oxidative (acetaldehyde) and nonoxidative metabolites (ethyl palmitate, ethyl oleate), rather than ethanol itself, mediate toxic injury. Exposure of pancreatic acini to ethanol blocks cholecystokinin (CCK)-8-stimulated apical exocytosis and redirects exocytosis to the basolateral plasma membrane...
Gurpreet Kaur et al.
Langmuir : the ACS journal of surfaces and colloids, 28(29), 10640-10652 (2012-06-23)
Microemulsions are important formulations in cosmetics and pharmaceutics and one peculiarity lies in the so-called "phase inversion" that takes place at a given water-to-oil concentration ratio and where the average curvature of the surfactant film is zero. In that context...
K J Dussan et al.
Bioresource technology, 101(24), 9542-9549 (2010-08-19)
Magnetic nanoparticles were prepared by coprecipitating Fe(2+) and Fe(3+) ions in a sodium hydroxide solution and used as support for lipase. The lipase-coated particles were applied in a reactive extraction process that allowed separation of the products formed during transesterification....
Neil Loftus et al.
Journal of proteome research, 10(2), 705-713 (2010-10-30)
Alcoholism is a complex disorder that, in man, appears to be genetically influenced, although the underlying genes and molecular pathways are not completely known. Here, the intragastric alcohol feeding model in rodents was used together with high mass accuracy LC-MS(n)...
Yizhen Chen et al.
International journal of pharmaceutics, 487(1-2), 17-24 (2015-04-07)
The toxicity and irritation associated with high amounts of surfactants restrict the extensive utilization of microemulsions. To address these shortcomings, employing mixed oils to enlarge microemulsion areas therefore reducing surfactant contents is a promising strategy. However, what kinds of mixed...
Shujauddin Changi et al.
ChemSusChem, 5(9), 1743-1757 (2012-08-29)
We examined the behavior of phenylalanine in high-temperature water (HTW) at 220, 250, 280, and 350 °C. Under these conditions, the major product is phenylethylamine. The minor products include styrene and phenylethanol (1-phenylethanol and 2-phenylethanol), which appear at higher temperatures and...
Claudia Dussaubat et al.
Journal of chemical ecology, 36(5), 522-525 (2010-04-20)
Pheromones in social insects play a key role in the regulation of group homoeostasis. It is well-established that parasites can modify hormone signaling of their host, but less is known about the effect of parasites on pheromone signaling in insect...
Corinne Loutelier-Bourhis et al.
Rapid communications in mass spectrometry : RCM, 26(11), 1265-1276 (2012-05-05)
The grafting of maleic anhydride onto fatty C=C double bonds is a well-known and used method to functionalize triglyceride molecules. Nevertheless, grafted products are not actually structurally well defined. In this work, the thermal grafting of maleic anhydride onto (un)saturated...
Y Ingrid Goh et al.
Alcohol (Fayetteville, N.Y.), 44(7-8), 629-634 (2010-06-30)
Meconium fatty acid ethyl esters (FAEEs) are sensitive and specific biomarkers for prenatal alcohol exposure (PAE) in pregnancy. We recently reported a 2.5% rate of FAEE positive meconium in a general population sample of infants born in the region of...
Hongda Ma et al.
Drug development and industrial pharmacy, 38(10), 1200-1206 (2012-04-20)
To improve the dissolution and oral absorption of Rhizoma corydalis decumbentis extracts (RCDE), a famous traditional Chinese herbal medicine which contains poorly water-soluble active components, self-emulsifying drug-delivery systems (SEDDS) were designed and evaluated in vitro and in vivo for the...
Zheng-fen Liang et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 32(11), 1697-1700 (2010-03-12)
To extract and analyze the liposoluble chemical constituents of the petroleum ether extraction and alcohol extraction from fruits of Harrisonia perforata. To analyze the liposoluble components by GC-MS. 29 compounds were identified from petroleum ether extraction, amounting to 69.67% of...
Brian S Bodnar et al.
The Journal of organic chemistry, 74(6), 2598-2600 (2009-02-18)
Significantly improved Bouveault-Blanc conditions for ester reduction have been developed using sodium in silica gel (Na-SG), a free-flowing powder that can be easily handled in the open atmosphere. Primary alcohols were prepared in excellent yield from a variety of aliphatic...
Jerry Nesamony et al.
Drug development and industrial pharmacy, 39(2), 240-251 (2012-04-07)
Water-in-oil microemulsions (w/o ME) are ideal for parenteral drug delivery. However, no such formulations have been tested for biocompatibility in in vitro cell cultures. Furthermore, sterilization of w/o MEs is a challenging process that has not been previously developed and...
H H Orak et al.
Food science and technology international = Ciencia y tecnologia de los alimentos internacional, 18(4), 391-402 (2012-04-24)
Antioxidant activity, colour and some nutritional properties of hot air and freeze-dried strawberry tree (Arbutus unedo L.) fruits were investigated. Additionally, the effects of two pre-treatments, namely ethyl oleate and water blanching, were compared in terms of drying characteristics. For...
Jia Ye et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 32(10), 1553-1555 (2010-02-02)
To investigate the massive hydrophobic constituents of Arnebia euchroma, and compare the similarities and differences of AE and AEZ from different sources. The hydrophobic constituents, AE01-1 and AEZ01-1, were obtained by the chromatograph of silica gel with elution of chloroform...
Andreas Braun et al.
Microbial cell factories, 11, 106-106 (2012-08-11)
Yarrowia lipolytica efficiently metabolizes and assimilates hydrophobic compounds such as n-alkanes and fatty acids. Efficient substrate uptake is enabled by naturally secreted emulsifiers and a modified cell surface hydrophobicity and protrusions formed by this yeast. We were examining the potential...
Zong-Ping Zheng et al.
Journal of agricultural and food chemistry, 63(5), 1615-1621 (2015-01-21)
Norartocarpetin is a flavone widely distributed in Moraceae plants with strong tyrosinase inhibitory activity. However, its poor solubility in aqueous systems and in food grade solvents (oils) limits its extensive applications. The aim of this study was to improve the...
Marwa Ahmed Sallam et al.
International journal of nanomedicine, 10, 4459-4478 (2015-07-24)
In this study, an optimized nanodispersible oral dosage form (containing a lactate ester) was developed for cilostazol (CZL). CZL is a phosphodiesterase inhibitor used for intermittent claudication. We aimed to improve the dissolution rate and absorption of CZL giving it...
Swati Pund et al.
International journal of pharmaceutics, 487(1-2), 148-156 (2015-04-15)
The present study is a mechanistic validation of 'proof of concept' of effective topical delivery of leflunomide (LFD) nanoemulgel for localized efficient treatment of psoriatic lesions as well as melanoma affected skin regions. Hyperproliferation of keratinocytes in psoriasis and symbiotic...
Khushwinder Kaur
Journal of the science of food and agriculture, 95(13), 2718-2728 (2014-11-25)
Inclusion complex formation between β-cyclodextrin (β-CD) and suitable guest molecules such as cholesterol (Ch) has regularly been exploited to design self-assembled structures. In the present study an effective nanoemulsion medium (lecithin/Tween 80/ethyl oleate/water) was selected for solubilizing and stabilizing Ch...
Jiangbo Hu et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(2), 556-564 (2014-06-26)
The purpose of this study was to develop and evaluate the supermolecular evodiamine (EVO) loaded water-in-oil nanoemulsions containing brucea javanica oil (NESEB) with enhanced physicochemical and biological characteristics. NESEB was fabricated by applying supermolecular phytosome nanotechnology and nanoemulsification technology together...

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